Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery (Q37914045)

25 August 2017

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title

Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery (English)

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25 August 2017

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Richard H Baltz

1

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25 August 2017

9 August 2011

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Journal of Industrial Microbiology & Biotechnology

25 August 2017

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25 August 2017

38

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25 August 2017

11

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25 August 2017

1747-1760

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Development of a genetic system for combinatorial biosynthesis of lipopeptides in Streptomyces fradiae and heterologous expression of the A54145 biosynthesis gene cluster

25 August 2017

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Basic local alignment search tool

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Renaissance in antibacterial discovery from actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Genomics and the ancient origins of the daptomycin biosynthetic gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Strain improvement in actinomycetes in the postgenomic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Solution structure of Rv2377c-founding member of the MbtH-like protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The vbs genes that direct synthesis of the siderophore vicibactin in Rhizobium leguminosarum: their expression in other genera requires ECF sigma factor RpoI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

New natural product biosynthetic chemistry discovered by genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Lyngbyatoxin biosynthesis: sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Identification of the biosynthetic gene cluster and an additional gene for resistance to the antituberculosis drug capreomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

MbtH-like proteins as integral components of bacterial nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Enzymatic tailoring of ornithine in the biosynthesis of the Rhizobium cyclic trihydroxamate siderophore vicibactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Enzymatic production of (-)-indolactam V by LtxB, a cytochrome P450 monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

N-acylation during glidobactin biosynthesis by the tridomain nonribosomal peptide synthetase module GlbF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Microevolutionary genomics of bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Molecular characterization of two genes from Streptomyces tendae Tü901 required for the formation of the 4-formyl-4-imidazolin-2-one-containing nucleoside moiety of the peptidyl nucleoside antibiotic nikkomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Molecular characterization of co-transcribed genes from Streptomyces tendae Tü901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Tandem action of glycosyltransferases in the maturation of vancomycin and teicoplanin aglycones: novel glycopeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Biosynthetic pathway for mannopeptimycins, lipoglycopeptide antibiotics active against drug-resistant gram-positive pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The lipopeptide antibiotic A54145 biosynthetic gene cluster from Streptomyces fradiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Sequencing and analysis of the biosynthetic gene cluster of the lipopeptide antibiotic Friulimicin in Actinoplanes friuliensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

A glutamic acid 3-methyltransferase encoded by an accessory gene locus important for daptomycin biosynthesis in Streptomyces roseosporus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Combinatorial biosynthesis of novel antibiotics related to daptomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Genetically engineered lipopeptide antibiotics related to A54145 and daptomycin with improved properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Trends in prokaryotic evolution revealed by comparison of closely related bacterial and archaeal genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The lyngbyatoxin biosynthetic assembly line: chain release by four-electron reduction of a dipeptidyl thioester to the corresponding alcohol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The gene cluster for the biosynthesis of the glycopeptide antibiotic A40926 by nonomuraea species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Organization of the teicoplanin gene cluster in Actinoplanes teichomyceticus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The small MbtH-like protein encoded by an internal gene of the balhimycin biosynthetic gene cluster is not required for glycopeptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Deciphering tuberactinomycin biosynthesis: isolation, sequencing, and annotation of the viomycin biosynthetic gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Cloning and characterization of sanO, a gene involved in nikkomycin biosynthesis in Streptomyces ansochromogenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Effects of deletions of mbtH-like genes on clorobiocin biosynthesis in Streptomyces coelicolor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

The enduracidin biosynthetic gene cluster from Streptomyces fungicidicus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Strain improvement of Streptomyces roseosporus for daptomycin production by rational screening of He-Ne laser and NTG induced mutants and kinetic modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Strategies for the discovery of new natural products by genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Activation of the pacidamycin PacL adenylation domain by MbtH-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-011-1022-8

MbtH-like protein-mediated cross-talk between non-ribosomal peptide antibiotic and siderophore biosynthetic pathways in Streptomyces coelicolor M145

21 January 2018

1 reference

12 December 2020

Complementation of daptomycin dptA and dptD deletion mutations in trans and production of hybrid lipopeptide antibiotics

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12 December 2020

Identification and functional characterization of phenylglycine biosynthetic genes involved in pristinamycin biosynthesis in Streptomyces pristinaespiralis.

1 reference

12 December 2020

Mining microbial genomes for new natural products and biosynthetic pathways

1 reference

12 December 2020

10.1007/S10295-011-1022-8

Identifiers

DOI

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25 August 2017

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PubMed ID

21826462