Strain improvement in actinomycetes in the postgenomic era. (Q37831207)

24 August 2017

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title

Strain improvement in actinomycetes in the postgenomic era. (English)

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24 August 2017

Richard H Baltz

1

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24 August 2017

21 January 2011

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Journal of Industrial Microbiology & Biotechnology

24 August 2017

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24 August 2017

38

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24 August 2017

6

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24 August 2017

657-666

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Development of a genetic system for combinatorial biosynthesis of lipopeptides in Streptomyces fradiae and heterologous expression of the A54145 biosynthesis gene cluster

24 August 2017

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genetic methods and strategies for secondary metabolite yield improvement in actinomycetes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Chapter 20. Biosynthesis and genetic engineering of lipopeptides in Streptomyces roseosporus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Differential roles of two SARP-encoding regulatory genes during tylosin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Regulation of tylosin biosynthesis involving 'SARP-helper' activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Antibiotic production improvement in the rare actinomycete Planobispora rosea by selection of mutants resistant to the aminoglycosides streptomycin and gentamycin and to rifamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Regulation of secondary metabolism in streptomycetes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Chapter 4. Analyzing the regulation of antibiotic production in streptomycetes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Identification and utility of FdmR1 as a Streptomyces antibiotic regulatory protein activator for fredericamycin production in Streptomyces griseus ATCC 49344 and heterologous hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Generation of high-yield rapamycin-producing strains through protoplasts-related techniques

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

New natural product biosynthetic chemistry discovered by genome mining

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Engineered production of iso-migrastatin in heterologous Streptomyces hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Heterologous expression of the biosynthetic gene clusters of coumermycin A(1), clorobiocin and caprazamycins in genetically modified Streptomyces coelicolor strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Deletion of a regulatory gene within the cpk gene cluster reveals novel antibacterial activity in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Integration site for Streptomyces phage phiBT1 and development of site-specific integrating vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Increased expression of ribosome recycling factor is responsible for the enhanced protein synthesis during the late growth phase in an antibiotic-overproducing Streptomyces coelicolor ribosomal rpsL mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Novel approach for improving the productivity of antibiotic-producing strains by inducing combined resistant mutations

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Contribution of rpoB2 RNA polymerase beta subunit gene to rifampin resistance in Nocardia species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genome-minimized Streptomyces host for the heterologous expression of secondary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Analysis of the integration function of the streptomycete bacteriophage φC31

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genetic and physiological characterization of rpoB mutations that activate antibiotic production in Streptomyces lividans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

High titer production of tetracenomycins by heterologous expression of the pathway in a Streptomyces cinnamonensis industrial monensin producer strain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Overexpression of ribosome recycling factor causes increased production of avermectin in Streptomyces avermitilis strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genetic factors that influence moenomycin production in streptomycetes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

The site-specific recombination system of actinophage TG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genomic basis for natural product biosynthetic diversity in the actinomycetes

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Combinatorial biosynthesis of novel antibiotics related to daptomycin

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

From microbial differentiation to ribosome engineering

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genetics of Streptomyces rimosus, the oxytetracycline producer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Production of hybrid 16-membered macrolides by expressing combinations of polyketide synthase genes in engineered Streptomyces fradiae hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Site-specific integration of the actinophage R4 genome into the chromosome of Streptomyces parvulus upon lysogenization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Site-specific recombination by phiC31 integrase and other large serine recombinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Expression analysis of the tylosin-biosynthetic gene cluster: pivotal regulatory role of the tylQ product.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Regulation of tylosin production and morphological differentiation in Streptomyces fradiae by TylP, a deduced gamma-butyrolactone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Positive control of tylosin biosynthesis: pivotal role of TylR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Activation of dormant bacterial genes by Nonomuraea sp. strain ATCC 39727 mutant-type RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Innovative approach for improvement of an antibiotic-overproducing industrial strain of Streptomyces albus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Antibiotic overproduction by rpsL and rsmG mutants of various actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Natural merodiploidy involving duplicated rpoB alleles affects secondary metabolism in a producer actinomycete.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Dramatic activation of antibiotic production in Streptomyces coelicolor by cumulative drug resistance mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Evolution of Streptomyces pristinaespiralis for resistance and production of pristinamycin by genome shuffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

A rifampicin resistance mutation in the rpoB gene confers ppGpp-independent antibiotic production in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genome shuffling leads to rapid phenotypic improvement in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-010-0934-Z

Genomic mining--a concept for the discovery of new bioactive natural products

21 January 2018

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12 December 2020

Inactivation of a transcriptional repressor during empirical improvement of the tylosin producer, Streptomyces fradiae

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12 December 2020

Gene expression in recombinant Streptomyces

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12 December 2020

Mining microbial genomes for new natural products and biosynthetic pathways

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12 December 2020

Control of tylosin biosynthesis in Streptomyces fradiae.

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12 December 2020

Regulation of tylosin production: role of a TylP-interactive ligand.

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12 December 2020

Rapid engineering of polyketide overproduction by gene transfer to industrially optimized strains

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12 December 2020

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

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12 December 2020

Renaissance in antibacterial discovery from actinomycetes

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12 December 2020

Isolation and characterization of the Streptomyces cattleya temperate phage TG1

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12 December 2020

10.1007/S10295-010-0934-Z

Identifiers

DOI

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24 August 2017

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PubMed ID

21253811