Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents (Q37865512)

24 August 2017

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title

Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents (English)

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24 August 2017

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John D Hayes

2

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author name string

Larry G Higgins

series ordinal

1

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PubMed ID

21495793

24 August 2017

language of work or name

English

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publication date

1 May 2011

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24 August 2017

Drug Metabolism Reviews

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24 August 2017

43

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24 August 2017

2

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24 August 2017

92-137

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Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis

24 August 2017

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Microsomal glutathione transferase 1 exhibits one-third-of-the-sites-reactivity towards glutathione

21 January 2018

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SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response

21 January 2018

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Glutathione S-transferases: reaction mechanism, structure, and function

21 January 2018

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Structure, catalytic mechanism, and evolution of the glutathione transferases

21 January 2018

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Glutathione transferases are structural and functional outliers in the thioredoxin fold

21 January 2018

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Radioimmunoassay of ligandin

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Ligandin heterogeneity: Evidence that the two non-identical subunits are the monomers of two distinct proteins

21 January 2018

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The aryl hydrocarbon receptor complex and the control of gene expression

21 January 2018

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Relationship between the soluble glutathione-dependent delta 5-3-ketosteroid isomerase and the glutathione S-transferases of the liver

21 January 2018

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21 January 2018

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Zeta, a novel class of glutathione transferases in a range of species from plants to humans

21 January 2018

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Identification, characterization, and crystal structure of the Omega class glutathione transferases

21 January 2018

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An enzyme from rat liver catalysing conjugations with glutathione

21 January 2018

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Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

21 January 2018

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Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice

21 January 2018

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Species differences in the inhibition of glutathione S-aryltransferase by phthaleins and dicarboxylic acids

21 January 2018

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Cross specificity in some vertebrate and insect glutathione-transferases with methyl parathion (dimethyl p-nitrophenyl phosphorothionate), 1-chloro-2,4-dinitro-benzene and s-crotonyl-N-acetylcysteamine as substrates

21 January 2018

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Microsomal Prostaglandin E Synthase-1 Is a Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production in the Rat Adjuvant-Induced Arthritis Model

21 January 2018

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Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex

21 January 2018

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A liver enzyme that conjugates sulfobromophthalein sodium with glutathione

21 January 2018

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Glutathione S-aryltransferase: the effect of treating male and female rats with phenobarbitone on the apparent kinetic parameters for the conjugation of 1,2-dichloro-4-nitrobenzene and 1-chloro-2,4-dinitrobenzene with glutathione

21 January 2018

1 reference

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Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages

21 January 2018

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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

21 January 2018

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Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

21 January 2018

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An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1

21 January 2018

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Roles for glutathione transferases in plant secondary metabolism.

21 January 2018

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Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

21 January 2018

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Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

21 January 2018

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Microarray analysis on Phase II drug metabolizing enzymes expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile or phenobarbital

21 January 2018

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The rat quinone reductase antioxidant response element. Identification of the nucleotide sequence required for basal and inducible activity and detection of antioxidant response element-binding proteins in hepatoma and non-hepatoma cell lines

21 January 2018

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Characterization of DNA complexes formed by the nuclear receptor constitutive androstane receptor

21 January 2018

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Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

21 January 2018

1 reference

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Two adjacent AP-1-like binding sites form the electrophile-responsive element of the murine glutathione S-transferase Ya subunit gene

21 January 2018

1 reference

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Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells

21 January 2018

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Effect of the antioxidant butylated hydroxytoluene (BHT) on the metabolism of the carcinogens N-2-fluorenylacetamide and N-hydroxy-N-2-fluorenylacetamide

21 January 2018

1 reference

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The identity of glutathione S-transferase B with ligandin, a major binding protein of liver

21 January 2018

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Developmental aspects of glutathione S-transferase B (ligandin) in rat liver

21 January 2018

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Differential induction of cytosolic epoxide hydrolase, microsomal epoxide hydrolase, and glutathione S-transferase activities

21 January 2018

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Up-regulation of prostaglandin E2 synthesis by interleukin-1beta in human orbital fibroblasts involves coordinate induction of prostaglandin-endoperoxide H synthase-2 and glutathione-dependent prostaglandin E2 synthase expression

21 January 2018

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The aryl hydrocarbon receptor complex

21 January 2018

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A novel glutathione transferase (13-13) isolated from the matrix of rat liver mitochondria having structural similarity to class theta enzymes

21 January 2018

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Purification and physical characterization of glutathione S-transferase K. Differential use of S-hexylglutathione and glutathione affinity matrices to isolate a novel glutathione S-transferase from rat liver

21 January 2018

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Purification and characterization of three forms of glutathione S-transferase A. A comparative study of the major YaYa-, YbYb- and YcYc-containing glutathione S-transferases

21 January 2018

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Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

21 January 2018

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NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

21 January 2018

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

21 January 2018

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Identification of two lithocholic acid-binding proteins. Separation of ligandin from glutathione S-transferase B

21 January 2018

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Cholic acid binding by glutathione S-transferases from rat liver cytosol

21 January 2018

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A study of the structures of the YaYa and YaYc glutathione S-transferases from rat liver cytosol. Evidence that the Ya monomer is responsible for lithocholate-binding activity

21 January 2018

1 reference

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Ethoxyquin-induced resistance to aflatoxin B1 in the rat is associated with the expression of a novel alpha-class glutathione S-transferase subunit, Yc2, which possesses high catalytic activity for aflatoxin B1-8,9-epoxide

21 January 2018

1 reference

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

21 January 2018

1 reference

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21 January 2018

Glutathione transferases

1 reference

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Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway

21 January 2018

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Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein

21 January 2018

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Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents

21 January 2018

1 reference

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Characterization of a phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene.

21 January 2018

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

21 January 2018

1 reference

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T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4.

21 January 2018

1 reference

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Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2

21 January 2018

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Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

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Characterization of a human class-Theta glutathione S-transferase with activity towards 1-menaphthyl sulphate

21 January 2018

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CCAAT enhancer-binding protein alpha suppresses the rat placental glutathione S-transferase gene in normal liver

21 January 2018

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Identification and characterization of a novel human microsomal glutathione S-transferase with leukotriene C4 synthase activity and significant sequence identity to 5-lipoxygenase-activating protein and leukotriene C4 synthase

21 January 2018

1 reference

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Identification and characterization of a novel microsomal enzyme with glutathione-dependent transferase and peroxidase activities

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG). A widespread protein superfamily

21 January 2018

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Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

21 January 2018

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Glutathione transferases: nomenclature

21 January 2018

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Structural basis for induced formation of the inflammatory mediator prostaglandin E2.

21 January 2018

1 reference

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Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene

21 January 2018

1 reference

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Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element

21 January 2018

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Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase

21 January 2018

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Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz

21 January 2018

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Drug induction of hepatic glutathione S-transferases in male and female rats*.

21 January 2018

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Role of hepatic anion-binding protein in bromsulphthalein conjugation

21 January 2018

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Nrf2 transcriptionally activates the mafG gene through an antioxidant response element

21 January 2018

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Nrf2: friend or foe for chemoprevention?

21 January 2018

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Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

21 January 2018

1 reference

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The isolation of carcinogen-binding protein from livers of rats given 4-dimethylaminoazobenzene

21 January 2018

1 reference

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Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13.1-13.2. Identification of the correct promoter region and demonstration of transcriptional regulation in response to oxidative stress

21 January 2018

1 reference

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Structural organization of the murine microsomal glutathione S-transferase gene (MGST1) from the 129/SvJ strain: identification of the promoter region and a comprehensive examination of tissue expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochondrial class kappa enzyme rGSTK1-1

21 January 2018

1 reference

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Modulation of pregnane X receptor- and electrophile responsive element-mediated gene expression by dietary polyphenolic compounds

21 January 2018

1 reference

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Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

21 January 2018

1 reference

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Cytoplasmic Accumulation of the Nuclear Receptor CAR by a Tetratricopeptide Repeat Protein in HepG2 Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Glutathione peroxidase activity in selenium-deficient rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Ligandin: a Hepatic Protein which Binds Steroids, Bilirubin, Carcinogens and a Number of Exogenous Organic Anions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Nomenclature for mammalian soluble glutathione transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Catalysis within the lipid bilayer-structure and mechanism of the MAPEG family of integral membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Differential induction of class alpha glutathione S-transferases in mouse liver by the anticarcinogenic antioxidant butylated hydroxyanisole. Purification and characterization of glutathione S-transferase Ya1Ya1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Human microsomal glutathione S-transferase. Its involvement in the conjugation of hexachlorobuta-1,3-diene with glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway: direct cross-talk between phase I and II drug-metabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Pathology of BHA- and BHT-induced lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Activation of microsomal glutathione S-transferase activity by sulfhydryl reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Effects of phenobarbital and 3-methylcholanthrene administration on glutathione-S-epoxide transferase activity in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Mouse liver and lung glutathione s-epoxide transferase: effects of phenobarbital and 3-methylcholanthrene administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Purification to homogeneity and the N-terminal sequence of human leukotriene C4 synthase: a homodimeric glutathione S-transferase composed of 18-kDa subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Molecular cloning and amino acid sequencing of rat liver class theta glutathione S-transferase Yrs-Yrs inactivating reactive sulfate esters of carcinogenic arylmethanols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Histone acetyltransferase MOZ acts as a co-activator of Nrf2-MafK and induces tumour marker gene expression during hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Dioxin receptor is a ligand-dependent E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Human MutSalpha specifically binds to DNA containing aminofluorene and acetylaminofluorene adducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Identification of key residues determining species differences in inhibitor binding of microsomal prostaglandin E synthase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Dioxin receptor and C/EBP regulate the function of the glutathione S-transferase Ya gene xenobiotic response element

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

5-lipoxygenase-activating protein gene expression. Key role of CCAAT/enhancer-binding proteins (C/EBP) in constitutive and tumor necrosis factor (TNF) alpha-induced expression in THP-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Organic anion-binding protein in rat liver: drug induction and its physiologic consequence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Modelling and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase family with similarity to prokaryotic 2-hydroxychromene-2-carboxylate isomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Multiple regulatory elements and phorbol 12-O-tetradecanoate 13-acetate responsiveness of the rat placental glutathione transferase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Membrane prostaglandin E synthase-1: a novel therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Microsomal glutathione S-transferases: selective up-regulation of leukotriene C4 synthase during lipopolysaccharide-induced pyresis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Sp1 and Sp3 function as key regulators of leukotriene C(4) synthase gene expression in the monocyte-like cell line, THP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Lipopolysaccharide down-regulates the leukotriene C4 synthase gene in the monocyte-like cell line, THP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Lipopolysaccharide induces 5-lipoxygenase-activating protein gene expression in THP-1 cells via a NF-kappaB and C/EBP-mediated mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

TNF-alpha downregulates the leukotriene C4 synthase gene in mononuclear phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Increased bioactivation of dihaloalkanes in rat liver due to induction of class theta glutathione S-transferase T1-1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

The human hGSTA5 gene encodes an enzymatically active protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

A ligand for the aryl hydrocarbon receptor isolated from lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

The potency of inducers of NAD(P)H:(quinone-acceptor) oxidoreductase parallels their efficiency as substrates for glutathione transferases. Structural and electronic correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Cloning and heterologous expression of cDNA encoding class Alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic α,β-unsaturated carbonyl compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Leukotriene C4 synthase promoter driven expression of GFP reveals cell specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Phenobarbital response elements of cytochrome P450 genes and nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Pi class glutathione S-transferase genes are regulated by Nrf 2 through an evolutionarily conserved regulatory element in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Mutagenesis of the active site of the human Theta-class glutathione transferase GSTT2-2: catalysis with different substrates involves different residues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Structural analysis of a rat liver glutathione S-transferase Ya gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Glutathione S-transferase Ya subunit gene: identification of regulatory elements required for basal level and inducible expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Localization of a phenobarbital-responsive element (PBRE) in the 5'-flanking region of the rat CYP2B2 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Functional antioxidant responsive elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Inhibition of Chemical Carcinogen-Induced Pulmonary Neoplasia by Butylated Hydroxyanisole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Inhibition of Carcinogenic and Toxic Effects of Polycyclic Hydrocarbons by Several Sulfur-Containing Compounds2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Brief Communication: Inhibition of Dimethylhydrazine-Induced Neoplasia of the Large Intestine by Disulfiram2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Regulation of CYP1A1 transcription via the metabolism of the tryptophan-derived 6-formylindolo[3,2-b]carbazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Inhibitory effect of butylated hydroxytoluene (BHT) on intestinal carcinogenesis in rats by azoxymethane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Molecular cloning and expression of human leukotriene-C4 synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Introducing the "TCDD-inducible AhR-Nrf2 gene battery"

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

Identification and isolation of a membrane protein necessary for leukotriene production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2011.567391

10.3109/03602532.2011.567391

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21495793