Lipopolysaccharide induces 5-lipoxygenase-activating protein gene expression in THP-1 cells via a NF-kappaB and C/EBP-mediated mechanism. (Q40476139)

20 September 2017

Lipopolysaccharide induces 5-lipoxygenase-activating protein gene expression in THP-1 cells via a NF-kappaB and C/EBP-mediated mechanism. (English)

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20 September 2017

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Kenneth J Serio

1

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PubMed ID

15625306

20 September 2017

K Veera Reddy

series ordinal

2

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PubMed ID

15625306

20 September 2017

Timothy D Bigby

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3

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20 September 2017

29 December 2004

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American Journal of Physiology - Cell Physiology

20 September 2017

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20 September 2017

288

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20 September 2017

5

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20 September 2017

C1125-33

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5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase

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Innate immune sensing and its roots: the story of endotoxin

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Prolonged lipopolysaccharide inhibits leukotriene synthesis in peritoneal macrophages: mediation by nitric oxide and prostaglandins.

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The induction of cyclooxygenase-2 mRNA in macrophages is biphasic and requires both CCAAT enhancer-binding protein beta (C/EBP beta ) and C/EBP delta transcription factors

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LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

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Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3)

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Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis

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Hyporesponsiveness to lipopolysaccharide alters the composition of NF-kappaB binding to the regulatory regions of inducible nitric oxide synthase gene

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High Efficiency DNA-Mediated Transformation of Primate Cells

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The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

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The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain

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Biological role of the CCAAT/enhancer-binding protein family of transcription factors

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Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases

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Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B4synthetic capacity

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5-lipoxygenase-activating protein is an arachidonate binding protein

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Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice

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Leukotriene A4 hydrolase in human bronchoalveolar lavage fluid

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KBF1 (p50 NF-kappa B homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cells

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The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity Functions

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5-lipoxygenase-activating protein gene expression. Key role of CCAAT/enhancer-binding proteins (C/EBP) in constitutive and tumor necrosis factor (TNF) alpha-induced expression in THP-1 cells

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Dexamethasone increases expression of 5-lipoxygenase and its activating protein in human monocytes and THP-1 cells

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Lymphocytes stimulate expression of 5-lipoxygenase and its activating protein in monocytes in vitro via granulocyte macrophage colony-stimulating factor and interleukin 3.

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Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities

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Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

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Sp1 and Sp3 function as key regulators of leukotriene C(4) synthase gene expression in the monocyte-like cell line, THP-1.

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Lipopolysaccharide down-regulates the leukotriene C4 synthase gene in the monocyte-like cell line, THP-1.

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Leukotriene D4Activates Alveolar Epithelial Na,K-ATPase and Increases Alveolar Fluid Clearance

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Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B

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10.1152/AJPCELL.00296.2004

21 January 2018

Identifiers

DOI

1 reference

20 September 2017

1 reference

PubMed ID

15625306