Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity (Q37865021)

24 August 2017

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title

Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity (English)

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24 August 2017

1

Jerzy Gubernator

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PubMed ID

21492058

24 August 2017

language of work or name

English

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publication date

15 April 2011

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Expert Opinion on Drug Delivery

24 August 2017

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24 August 2017

8

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24 August 2017

5

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24 August 2017

565-580

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The complement system in liposome clearance: Can complement deposition be inhibited?

24 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Serum independent liposome uptake by mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Effect of serum components from different species on destabilizing hydrogenated phosphatidylcholine-based liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Vesicles of variable sizes produced by a rapid extrusion procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Sterically stabilized liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Recent advances in targeted anti-vasculature therapy: the neuroblastoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Ligand-targeted liposomal therapies of neuroblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Ligand-targeted liposomal anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Stability of liposomal doxorubicin formulations: problems and prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

The mechanism of vesicle formation

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Comparative properties and methods of preparation of lipid vesicles (liposomes).

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Single bilayer liposomes prepared without sonication

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Accumulation of doxorubicin and other lipophilic amines into large unilamellar vesicles in response to transmembrane pH gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Transport of anthracyclines and mitoxantrone across membranes by a flip-flop mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Uptake of basic amino acids and peptides into liposomes in response to transmembrane pH gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Dopamine accumulation in large unilamellar vesicle systems induced by transmembrane ion gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

pH gradient loading of anthracyclines into cholesterol-free liposomes: enhancing drug loading rates through use of ethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Substantial increases in idarubicin plasma concentration by liposome encapsulation mediates improved antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Improved retention of idarubicin after intravenous injection obtained for cholesterol-free liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Tumor necrosis factor alpha mediates homogeneous distribution of liposomes in murine melanoma that contributes to a better tumor response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Determination of doxorubicin levels in whole tumor and tumor nuclei in murine breast cancer tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Multifunctional nanocarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

The encapsulation of idarubicin within liposomes using the novel EDTA ion gradient method ensures improved drug retention in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Anomalous solubility behavior of the antibiotic ciprofloxacin encapsulated in liposomes: a 1H-NMR study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Liposome drugs' loading efficiency: a working model based on loading conditions and drug's physicochemical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

The response of fluorescent amines to pH gradients across liposome membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Ca2+ transport properties of ionophores A23187, ionomycin, and 4-BrA23187 in a well defined model system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Effects of pH conditions on Ca2+ transport catalyzed by ionophores A23187, 4-BrA23187, and ionomycin suggest problems with common applications of these compounds in biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Biological applications of ionophores

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Ni2+-mediated mitoxantrone encapsulation: improved efficacy of fast release formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Copper ion-mediated liposomal encapsulation of mitoxantrone: the role of anions in drug loading, retention and release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

In vitro and in vivo characterization of doxorubicin and vincristine coencapsulated within liposomes through use of transition metal ion complexation and pH gradient loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

A novel liposomal irinotecan formulation with significant anti-tumour activity: use of the divalent cation ionophore A23187 and copper-containing liposomes to improve drug retention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Copper-topotecan complexation mediates drug accumulation into liposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Drug release rate influences the pharmacokinetics, biodistribution, therapeutic activity, and toxicity of pegylated liposomal doxorubicin formulations in murine breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Formation of drug-arylsulfonate complexes inside liposomes: a novel approach to improve drug retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

An evaluation of transmembrane ion gradient-mediated encapsulation of topotecan within liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Intravesical idarubicin: a dose-finding study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Size of thermosensitive liposomes influences content release

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Identification of vesicle properties that enhance the antitumour activity of liposomal vincristine against murine L1210 leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Liposome-encapsulated vincristine, vinblastine and vinorelbine: a comparative study of drug loading and retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Novel formulations of taxanes: a review. Old wine in a new bottle?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Optimizing combination chemotherapy by controlling drug ratios

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Ionophore-mediated loading of Ca2+ into large unilamellar vesicles in response to transmembrane pH gradients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

Diffusion of Small Non-Electrolytes across Liposome Membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.566552

10.1517/17425247.2011.566552

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21492058