Cancer therapy based on oncogene addiction (Q37863612)

24 August 2017

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title

Cancer therapy based on oncogene addiction (English)

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24 August 2017

Frank McCormick

1

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24 August 2017

1 May 2011

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Journal of Surgical Oncology

24 August 2017

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24 August 2017

103

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24 August 2017

6

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24 August 2017

464-467

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Making progress through molecular attacks on cancer

24 August 2017

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Cancer: mixing cocktails.

21 January 2018

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Dynamics of chronic myeloid leukaemia.

21 January 2018

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21 January 2018

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Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

21 January 2018

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21 January 2018

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BRAF mutation predicts sensitivity to MEK inhibition

21 January 2018

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Phosphatidylinositol 3-kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor NVP-BEZ235.

21 January 2018

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Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib

21 January 2018

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(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

21 January 2018

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Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back.

21 January 2018

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Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition

21 January 2018

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Specific protection against breast cancers by cyclin D1 ablation

21 January 2018

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Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice

21 January 2018

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RalGDS is required for tumor formation in a model of skin carcinogenesis.

21 January 2018

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Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

21 January 2018

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Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

21 January 2018

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Cancer targets in the Ras pathway

21 January 2018

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Discovery of a novel Raf kinase inhibitor

21 January 2018

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Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors

21 January 2018

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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

21 January 2018

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Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib.

21 January 2018

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How blocking Raf activates the MAPK pathway

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JSO.21749

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24 August 2017

1 reference

PubMed ID

21480237