BRAF mutation predicts sensitivity to MEK inhibition (Q29614281)

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30 April 2017

5

Getz G

1 reference

30 April 2017

2

Garraway LA

1 reference

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30 April 2017

author name string

Solit DB

1

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30 April 2017

Pratilas CA

3

1 reference

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30 April 2017

Sawai A

4

1 reference

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30 April 2017

Basso A

6

1 reference

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30 April 2017

Ye Q

7

1 reference

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30 April 2017

Lobo JM

8

1 reference

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30 April 2017

She Y

9

1 reference

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30 April 2017

Osman I

10

1 reference

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30 April 2017

Golub TR

11

1 reference

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30 April 2017

Sebolt-Leopold J

12

1 reference

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30 April 2017

Sellers WR

13

1 reference

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30 April 2017

Rosen N

14

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30 April 2017

publication date

19 January 2006

1 reference

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30 April 2017

language of work or name

1 reference

30 April 2017

1 reference

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30 April 2017

volume

439

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issue

7074

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30 April 2017

page(s)

358-62

1 reference

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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

30 April 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Mutations of the BRAF gene in human cancer

30 April 2017

1 reference

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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

RalGDS is required for tumor formation in a model of skin carcinogenesis.

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Targeting the mitogen-activated protein kinase cascade to treat cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

B-RAF is a therapeutic target in melanoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

V599EB-RAF is an oncogene in melanocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Distinct requirements for Ras oncogenesis in human versus mouse cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Induction of cyclin D1 overexpression by activated ras.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Morphological and immunocytochemical characteristics of human tumor cell lines for use in a disease-oriented anticancer drug screen

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Anthrax lethal factor proteolysis and inactivation of MAPK kinase.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3306236

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

26 November 2018

1 reference

12 December 2020

Resorcylic acid lactones: naturally occurring potent and selective inhibitors of MEK

1 reference

12 December 2020

BRAF and RAS mutations in human lung cancer and melanoma

1 reference

12 December 2020

Production of a family of kinase-inhibiting lactones from fungal fermentations

1 reference

12 December 2020

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16273091

Identifiers

2 references

30 April 2017

Dimensions Publication ID

1012130507

0 references

Fatcat ID

release_ijq6izcuibdz7lshvn3pket2oe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ijq6izcuibdz7lshvn3pket2oe

24 November 2022

mapped directly with Wikidata item

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16273091

2 references

30 April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=16273091

PubMed publication ID

2 references

30 April 2017