Azole resistance in Aspergillus fumigatus: a new challenge in the management of invasive aspergillosis? (Q37859397)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21449843%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

review article

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title

Azole resistance in Aspergillus fumigatus: a new challenge in the management of invasive aspergillosis? (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21449843%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

main subject

Aspergillus fumigatus

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1

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27 January 2020

Willem Melchers

series ordinal

2

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27 January 2020

Paul E. Verweij

series ordinal

3

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27 January 2020

3

Paul E Verweij

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24 August 2017

2

Willem J G Melchers

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24 August 2017

language of work or name

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1 March 2011

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27 January 2020

number of pages

13

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based on heuristic

inferred from page(s)

published in

Future Microbiology

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27 January 2020

volume

6

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27 January 2020

page(s)

335-347

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27 January 2020

issue

3

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Polyphasic taxonomy of Aspergillus section Fumigati and its teleomorph Neosartorya

27 January 2020

cites work

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Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence.

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Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure

21 January 2018

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Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs

21 January 2018

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A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

21 January 2018

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Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism

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Azole-resistant central nervous system aspergillosis.

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Susceptibility to five antifungals of Aspergillus fumigatus strains isolated from chronically colonised cystic fibrosis patients receiving azole therapy

21 January 2018

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Epidemiological cutoffs and cross-resistance to azole drugs in Aspergillus fumigatus.

21 January 2018

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Azole-resistance in Aspergillus: proposed nomenclature and breakpoints

21 January 2018

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EUCAST Technical Note on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for conidia–forming moulds

21 January 2018

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Susceptibility testing of sequential isolates of Aspergillus fumigatus recovered from treated patients.

21 January 2018

1 reference

Breakthrough Aspergillus fumigatus and Candida albicans double infection during caspofungin treatment: laboratory characteristics and implication for susceptibility testing.

21 January 2018

1 reference

A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus

21 January 2018

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Fungal echinocandin resistance.

21 January 2018

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Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B.

21 January 2018

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Aspergillus lentulus sp. nov., a new sibling species of A. fumigatus

21 January 2018

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Molecular studies reveal frequent misidentification of Aspergillus fumigatus by morphotyping

21 January 2018

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Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates

21 January 2018

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Possible environmental origin of resistance of Aspergillus fumigatus to medical triazoles

21 January 2018

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Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain

21 January 2018

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Update on antifungal drug resistance mechanisms of Aspergillus fumigatus

21 January 2018

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The ergosterol biosynthesis pathway, transporter genes, and azole resistance in Aspergillus fumigatus.

21 January 2018

1 reference

Multiple resistance mechanisms among Aspergillus fumigatus mutants with high-level resistance to itraconazole.

21 January 2018

1 reference

Increased expression of a novel Aspergillus fumigatus ABC transporter gene, atrF, in the presence of itraconazole in an itraconazole resistant clinical isolate

21 January 2018

1 reference

A novel method used to delete a new Aspergillus fumigatus ABC transporter-encoding gene.

21 January 2018

1 reference

A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus

21 January 2018

1 reference

A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus

21 January 2018

1 reference

Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species

21 January 2018

1 reference

Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.

21 January 2018

1 reference

Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding.

21 January 2018

1 reference

A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus

21 January 2018

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Cytochromes P450: a success story

21 January 2018

1 reference

Modeling cytochrome P450 14 alpha demethylase (Candida albicans) from P450cam.

21 January 2018

1 reference

Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14alpha-demethylase

21 January 2018

1 reference

Modeling and interactions of Aspergillus fumigatus lanosterol 14-alpha demethylase 'A' with azole antifungals.

21 January 2018

1 reference

Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling.

21 January 2018

1 reference

High prevalence of antifungal resistance in Candida spp. from patients with AIDS.

21 January 2018

1 reference

Evolution of antifungal-drug resistance: mechanisms and pathogen fitness

21 January 2018

1 reference

Is there a serious risk of resistance development to azoles among fungi due to the widespread use and long-term application of azole antifungals in medicine?

21 January 2018

1 reference

Will resistance in fungi emerge on a scale similar to that seen in bacteria?

21 January 2018

1 reference

Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene.

21 January 2018

1 reference

Discovery of a sexual cycle in the opportunistic fungal pathogen Aspergillus fumigatus

21 January 2018

1 reference

Rapid, high-throughput, multiplex, real-time PCR for identification of mutations in the cyp51A gene of Aspergillus fumigatus that confer resistance to itraconazole

21 January 2018

1 reference

Rapid detection of triazole antifungal resistance in Aspergillus fumigatus

21 January 2018

1 reference

In-vitro activities of amphotericin B, itraconazole and voriconazole against 150 clinical and environmental Aspergillus fumigatus isolates.

21 January 2018

1 reference

In-vitro susceptibility of Aspergillus spp. isolates to amphotericin B and itraconazole

21 January 2018

1 reference

Nationwide survey of in vitro activities of itraconazole and voriconazole against clinical Aspergillus fumigatus isolates cultured between 1945 and 1998.

21 January 2018

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Azole cross-resistance in Aspergillus fumigatus

21 January 2018

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In vitro susceptibilities of clinical isolates of Candida species, Cryptococcus neoformans, and Aspergillus species to itraconazole: global survey of 9,359 isolates tested by clinical and laboratory standards institute broth microdilution methods

21 January 2018

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Antifungal susceptibilities of clinical isolates of Candida species, Cryptococcus neoformans, and Aspergillus species from Taiwan: surveillance of multicenter antimicrobial resistance in Taiwan program data from 2003

21 January 2018

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Clinical isolates of Aspergillus species remain fully susceptible to voriconazole in the post-voriconazole era.

21 January 2018

1 reference

Activities of voriconazole, itraconazole and amphotericin B in vitro against 590 moulds from 323 patients in the voriconazole Phase III clinical studies

21 January 2018

1 reference

Wild-type MIC distribution and epidemiological cutoff values for Aspergillus fumigatus and three triazoles as determined by the Clinical and Laboratory Standards Institute broth microdilution methods

21 January 2018

1 reference

Patterns of susceptibility of Aspergillus isolates recovered from patients enrolled in the Transplant-Associated Infection Surveillance Network.

21 January 2018

1 reference

Multi-azole resistance in Aspergillus fumigatus

21 January 2018

1 reference

Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/FMB.11.4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21449843%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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