Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility. (Q33836567)

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12 January 2020

title

Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility (English)

1 reference

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14-alpha sterol demethylase

12 January 2020

main subject

Aspergillus fumigatus

0 references

1 reference

6 February 2019

3

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12 January 2020

author name string

Mellado E

1

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12 January 2020

Garcia-Effron G

2

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12 January 2020

Alcazar-Fuoli L

4

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12 January 2020

Cuenca-Estrella M

5

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12 January 2020

Rodriguez-Tudela JL

6

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12 January 2020

language of work or name

English

0 references

publication date

1 June 2005

1 reference

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Antimicrobial Agents and Chemotherapy

12 January 2020

published in

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volume

49

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12 January 2020

page(s)

2536-2538

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12 January 2020

issue

6

1 reference

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Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs

12 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140498

Interlaboratory evaluation of hematocytometer method of inoculum preparation for testing antifungal susceptibilities of filamentous fungi

28 July 2018

1 reference

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Candida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents

28 July 2018

1 reference

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A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140498

In vitro and in vivo effects of 14alpha-demethylase (ERG11) depletion in Candida glabrata

28 July 2018

1 reference

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Inoculum standardization for antifungal susceptibility testing of filamentous fungi pathogenic for humans

28 July 2018

1 reference

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Influence of glucose supplementation and inoculum size on growth kinetics and antifungal susceptibility testing of Candida spp

28 July 2018

1 reference

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Quantitation of Candida albicans ergosterol content improves the correlation between in vitro antifungal susceptibility test results and in vivo outcome after fluconazole treatment in a murine model of invasive candidiasis

28 July 2018

1 reference

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Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility

28 July 2018

1 reference

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Virulence of Aspergillus fumigatus double mutants lacking restriction and an alkaline protease in a low-dose model of invasive pulmonary aspergillosis.

28 July 2018

1 reference

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Transformation of Aspergillus nidulans with the hygromycin-resistance gene, hph.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140498

Identification of two different 14-alpha sterol demethylase-related genes (cyp51A and cyp51B) in Aspergillus fumigatus and other Aspergillus species

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1140498

A new mathematical model for relative quantification in real-time RT-PCR

29 October 2018

1 reference

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Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5'-monophosphate decarboxylase.

29 October 2018

1 reference

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Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15917566

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.49.6.2536-2538.2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15917566%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15917566%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference