Prevention and correction mechanisms behind anaphase synchrony: implications for the genesis of aneuploidy (Q37838177)

24 August 2017

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title

Prevention and correction mechanisms behind anaphase synchrony: implications for the genesis of aneuploidy (English)

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24 August 2017

I Matos

1

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PubMed ID

21304244

24 August 2017

H Maiato

series ordinal

2

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24 August 2017

8 February 2011

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Cytogenetics and Genome Research

24 August 2017

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24 August 2017

133

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24 August 2017

243-253

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24 August 2017

2-4

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Aurora B regulates MCAK at the mitotic centromere

24 August 2017

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Genome stability is ensured by temporal control of kinetochore-microtubule dynamics

21 January 2018

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Deviant kinetochore microtubule dynamics underlie chromosomal instability.

21 January 2018

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The ability to survive mitosis in the presence of microtubule poisons differs significantly between human nontransformed (RPE-1) and cancer (U2OS, HeLa) cells

21 January 2018

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Chromosome congression in the absence of kinetochore fibres

21 January 2018

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TOGp regulates microtubule assembly and density during mitosis and contributes to chromosome directional instability.

21 January 2018

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Molecular architecture of the kinetochore-microtubule interface

21 January 2018

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The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

21 January 2018

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Detection and correction of merotelic kinetochore orientation by Aurora B and its partners

21 January 2018

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Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells

21 January 2018

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Ase1/Prc1-dependent spindle elongation corrects merotely during anaphase in fission yeast

21 January 2018

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Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

21 January 2018

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Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules

21 January 2018

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

21 January 2018

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Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient

21 January 2018

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CLIPs and CLASPs and cellular dynamics

21 January 2018

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Limiting the proliferation of polyploid cells

21 January 2018

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Efficient mitosis in human cells lacking poleward microtubule flux

21 January 2018

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Tetraploidy, aneuploidy and cancer

21 January 2018

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A mechanism linking extra centrosomes to chromosomal instability

21 January 2018

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Microtubules of the kinetochore fiber turn over in metaphase but not in anaphase

21 January 2018

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Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1.

21 January 2018

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To err (meiotically) is human: the genesis of human aneuploidy

21 January 2018

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Positive feedback sharpens the anaphase switch

21 January 2018

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Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

21 January 2018

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Chromosomes can congress to the metaphase plate before biorientation

21 January 2018

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Centromere tension: a divisive issue

21 January 2018

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Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

21 January 2018

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Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

21 January 2018

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Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates

21 January 2018

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Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase

21 January 2018

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The centromere geometry essential for keeping mitosis error free is controlled by spindle forces

21 January 2018

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Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microtubule turnover and poleward flux.

21 January 2018

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Aurora B kinase cooperates with CENP-E to promote timely anaphase onset.

21 January 2018

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The perpetual movements of anaphase.

21 January 2018

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Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

21 January 2018

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Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis

21 January 2018

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Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres

21 January 2018

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The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.

21 January 2018

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CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity

21 January 2018

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Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity

21 January 2018

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Synchronizing chromosome segregation by flux-dependent force equalization at kinetochores.

21 January 2018

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Chromokinesins: multitalented players in mitosis

21 January 2018

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Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset

21 January 2018

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Co-ordination of cytokinesis with chromosome segregation

21 January 2018

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A mechanism for chromosome segregation sensing by the NoCut checkpoint.

21 January 2018

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Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1).

21 January 2018

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Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment

21 January 2018

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Sli15(INCENP) dephosphorylation prevents mitotic checkpoint reengagement due to loss of tension at anaphase onset

21 January 2018

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The spindle-assembly checkpoint in space and time

21 January 2018

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Cohesin: its roles and mechanisms

21 January 2018

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Sister chromatid tension and the spindle assembly checkpoint

21 January 2018

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Elements of error correction in mitosis: microtubule capture, release, and tension

21 January 2018

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The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage.

21 January 2018

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The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.

21 January 2018

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The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics

21 January 2018

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Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei

21 January 2018

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Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function

21 January 2018

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Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

21 January 2018

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

21 January 2018

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Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase

21 January 2018

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Chromosomal passengers: conducting cell division

21 January 2018

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Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.

21 January 2018

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Bub1 is activated by the protein kinase p90(Rsk) during Xenopus oocyte maturation

21 January 2018

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Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

21 January 2018

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Aurora B-mediated abscission checkpoint protects against tetraploidization

21 January 2018

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Finishing mitosis, one step at a time.

21 January 2018

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Genetic activities in micronuclei: is the DNA entrapped in micronuclei lost for the cell?

21 January 2018

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Examining the link between chromosomal instability and aneuploidy in human cells

21 January 2018

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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

21 January 2018

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Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly

21 January 2018

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Kinetochore stretching inactivates the spindle assembly checkpoint

21 January 2018

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Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface

21 January 2018

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Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments

21 January 2018

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Kinetochore microtubule dynamics and the metaphase-anaphase transition

21 January 2018

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Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function

21 January 2018

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Chromatin-associated Protein Phosphatase 1 Regulates Aurora-B and Histone H3 Phosphorylation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000323803

1 reference

24 August 2017

1 reference

PubMed ID

21304244