Molecular architecture of the kinetochore-microtubule interface (Q29620741)

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30 December 2019

review article

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title

Molecular architecture of the kinetochore-microtubule interface (English)

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30 December 2019

author name string

Arshad Desai

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2

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publication date

1 January 2008

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Nature Reviews Molecular Cell Biology

30 December 2019

published in

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9

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33-46

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1

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Using electron microscopy to understand functional mechanisms of chromosome alignment on the mitotic spindle

30 December 2019

cites work

1 reference

The fine structure of the kinetochore of a mammalian cell in vitro

31 March 2020

1 reference

CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells

31 March 2020

1 reference

The outer plate in vertebrate kinetochores is a flexible network with multiple microtubule interactions

31 March 2020

1 reference

Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma

31 March 2020

1 reference

Purification of the centromere-specific protein CENP-A and demonstration that it is a distinctive histone

31 March 2020

1 reference

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere

31 March 2020

1 reference

CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase

31 March 2020

1 reference

The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis

31 March 2020

1 reference

Structure, Function, and Regulation of Budding Yeast Kinetochores

31 March 2020

1 reference

Structures and functions of yeast kinetochore complexes

31 March 2020

1 reference

Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway

31 March 2020

1 reference

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

31 March 2020

1 reference

Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.

31 March 2020

1 reference

Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase

31 March 2020

1 reference

The human CENP-A centromeric nucleosome-associated complex

31 March 2020

1 reference

Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry

31 March 2020

1 reference

Proteome analysis of the human mitotic spindle

31 March 2020

1 reference

The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation

31 March 2020

1 reference

Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes

31 March 2020

1 reference

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres

31 March 2020

1 reference

"Holo"er than thou: chromosome segregation and kinetochore function in C. elegans

31 March 2020

1 reference

A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite

31 March 2020

1 reference

CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA.

31 March 2020

1 reference

Neocentromeres: role in human disease, evolution, and centromere study

31 March 2020

1 reference

The case for epigenetic effects on centromere identity and function.

31 March 2020

1 reference

Conserved organization of centromeric chromatin in flies and humans

31 March 2020

1 reference

Proteolysis contributes to the exclusive centromere localization of the yeast Cse4/CENP-A histone H3 variant

31 March 2020

1 reference

Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores

31 March 2020

1 reference

Structural determinants for generating centromeric chromatin

31 March 2020

1 reference

An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes

31 March 2020

1 reference

Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain

31 March 2020

1 reference

Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1

31 March 2020

1 reference

Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin

31 March 2020

1 reference

Genes required for mitotic spindle assembly in Drosophila S2 cells

31 March 2020

1 reference

Propagation of centromeric chromatin requires exit from mitosis.

31 March 2020

1 reference

Incorporation of Drosophila CID/CENP-A and CENP-C into centromeres during early embryonic anaphase

31 March 2020

1 reference

Stretching it: putting the CEN(P-A) in centromere

31 March 2020

1 reference

Chaperone-mediated assembly of centromeric chromatin in vitro

31 March 2020

1 reference

Nonhistone Scm3 and histones CenH3-H4 assemble the core of centromere-specific nucleosomes

31 March 2020

1 reference

Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore

31 March 2020

1 reference

Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization

31 March 2020

1 reference

Architecture of the budding yeast kinetochore reveals a conserved molecular core

31 March 2020

1 reference

Tetrameric structure of centromeric nucleosomes in interphase Drosophila cells

31 March 2020

1 reference

Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells

31 March 2020

1 reference

CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1.

31 March 2020

1 reference

Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells

31 March 2020

1 reference

Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae

31 March 2020

1 reference

Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast

31 March 2020

1 reference

De novo kinetochore assembly requires the centromeric histone H3 variant.

31 March 2020

1 reference

A histone-H3-like protein in C. elegans

31 March 2020

1 reference

Functional analysis of kinetochore assembly in Caenorhabditis elegans.

31 March 2020

1 reference

The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions

31 March 2020

1 reference

A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1

31 March 2020

1 reference

The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation.

31 March 2020

1 reference

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

31 March 2020

1 reference

Interactions between Centromere Complexes inSaccharomyces cerevisiae

31 March 2020

1 reference

KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans

31 March 2020

1 reference

The conserved Spc7 protein is required for spindle integrity and links kinetochore complexes in fission yeast

31 March 2020

1 reference

CENP-C is involved in chromosome segregation, mitotic checkpoint function, and kinetochore assembly

31 March 2020

1 reference

Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells

31 March 2020

1 reference

Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis

31 March 2020

1 reference

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

31 March 2020

1 reference

Rod-Zw10-Zwilch: a key player in the spindle checkpoint

31 March 2020

1 reference

The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis

31 March 2020

1 reference

Molecular architecture of a kinetochore-microtubule attachment site

31 March 2020

1 reference

hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells

31 March 2020

1 reference

The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity

31 March 2020

1 reference

Molecular organization of the Ndc80 complex, an essential kinetochore component

31 March 2020

1 reference

Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore

31 March 2020

1 reference

Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites

31 March 2020

1 reference

The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment

31 March 2020

1 reference

Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain

31 March 2020

1 reference

Kinetochores use a novel mechanism for coordinating the dynamics of individual microtubules.

31 March 2020

1 reference

Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation

31 March 2020

1 reference

Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint

31 March 2020

1 reference

CENP-F is a novel microtubule-binding protein that is essential for kinetochore attachments and affects the duration of the mitotic checkpoint delay.

31 March 2020

1 reference

Cenp-F links kinetochores to Ndel1/Nde1/Lis1/dynein microtubule motor complexes

31 March 2020

1 reference

Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2

31 March 2020

1 reference

Xenopus Cep57 is a novel kinetochore component involved in microtubule attachment

31 March 2020

1 reference

Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis

31 March 2020

1 reference

The dynamic kinetochore-microtubule interface

31 March 2020

1 reference

Microtubule polymerases and depolymerases

31 March 2020

1 reference

Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics

31 March 2020

1 reference

Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres

31 March 2020

1 reference

The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation.

31 March 2020

1 reference

CLIP-170 facilitates the formation of kinetochore-microtubule attachments

31 March 2020

1 reference

The Schizosaccharomyces pombe EB1 Homolog Mal3p Binds and Stabilizes the Microtubule Lattice Seam

31 March 2020

1 reference

MAPping the eukaryotic tree of life: structure, function, and evolution of the MAP215/Dis1 family of microtubule-associated proteins

31 March 2020

1 reference

Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro

31 March 2020

1 reference

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

31 March 2020

1 reference

The yeast DASH complex forms closed rings on microtubules.

31 March 2020

1 reference

Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex

31 March 2020

1 reference

Protein arms in the kinetochore-microtubule interface of the yeast DASH complex

31 March 2020

1 reference

Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms

31 March 2020

1 reference

The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends.

31 March 2020

1 reference

The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movement

31 March 2020

1 reference

Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis

31 March 2020

1 reference

Molecular mechanisms of microtubule-dependent kinetochore transport toward spindle poles

31 March 2020

1 reference

The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast

31 March 2020

1 reference

Chromosome motion during attachment to the vertebrate spindle: initial saltatory-like behavior of chromosomes and quantitative analysis of force production by nascent kinetochore fibers

31 March 2020

1 reference

Chromosomes can congress to the metaphase plate before biorientation

31 March 2020

1 reference

Analysis of kinesin motor function at budding yeast kinetochores.

31 March 2020

1 reference

CENP-E function at kinetochores is essential for chromosome alignment.

31 March 2020

1 reference

CENP-E as an essential component of the mitotic checkpoint in vitro.

31 March 2020

1 reference

A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.

31 March 2020

1 reference

PICH, a centromere-associated SNF2 family ATPase, is regulated by Plk1 and required for the spindle checkpoint

31 March 2020

1 reference

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

31 March 2020

1 reference

Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore

31 March 2020

1 reference

The spindle-assembly checkpoint in space and time

31 March 2020

1 reference

Roles of polo-like kinase 1 in the assembly of functional mitotic spindles

31 March 2020

1 reference

Chemical genetics reveals a role for Mps1 kinase in kinetochore attachment during mitosis

31 March 2020

1 reference

Ablation of the spindle assembly checkpoint by a compound targeting Mps1.

31 March 2020

1 reference

A dual role for Bub1 in the spindle checkpoint and chromosome congression

31 March 2020

1 reference

Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression

31 March 2020

1 reference

The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments

31 March 2020

1 reference

Unraveling cell division mechanisms with small-molecule inhibitors

31 March 2020

1 reference

Chromosomal passengers: conducting cell division

31 March 2020

1 reference

A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension

31 March 2020

1 reference

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections

31 March 2020

1 reference

Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p

31 March 2020

1 reference

Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity

31 March 2020

1 reference

Aurora B regulates MCAK at the mitotic centromere

31 March 2020

1 reference

Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

31 March 2020

1 reference

Polo-like kinases: a team in control of the division

31 March 2020

1 reference

Polo-like kinase 1 creates the tension-sensing 3F3/2 phosphoepitope and modulates the association of spindle-checkpoint proteins at kinetochores

31 March 2020

1 reference

Plx1 is the 3F3/2 kinase responsible for targeting spindle checkpoint proteins to kinetochores

31 March 2020

1 reference

Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation

31 March 2020

1 reference

NudC is required for Plk1 targeting to the kinetochore and chromosome congression

31 March 2020

1 reference

Time-lapse imaging reveals dynamic relocalization of PP1gamma throughout the mammalian cell cycle

31 March 2020

1 reference

Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7.

31 March 2020

1 reference

Shugoshin collaborates with protein phosphatase 2A to protect cohesin

31 March 2020

1 reference

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

31 March 2020

1 reference

PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation

31 March 2020

1 reference

Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments

31 March 2020

1 reference

The Set1 methyltransferase opposes Ipl1 aurora kinase functions in chromosome segregation

31 March 2020

1 reference

Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation

31 March 2020

1 reference

SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles

31 March 2020

1 reference

Ran-GTP regulates kinetochore attachment in somatic cells.

31 March 2020

1 reference

Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi

31 March 2020

1 reference

Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network

31 March 2020

1 reference

The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions

31 March 2020

1 reference

The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly

31 March 2020

1 reference

ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division

31 March 2020

1 reference

MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly

31 March 2020

1 reference

MEL-28 is downstream of the Ran cycle and is required for nuclear-envelope function and chromatin maintenance.

31 March 2020

1 reference

31 March 2020

1 reference

Does aneuploidy cause cancer?

31 March 2020

1 reference

On the road to cancer: aneuploidy and the mitotic checkpoint

31 March 2020

1 reference

Characterization of the MLL partner gene AF15q14 involved in t(11;15)(q23;q14).

31 March 2020

1 reference

Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers

31 March 2020

1 reference

HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis

31 March 2020

1 reference

Centromere protein H is up-regulated in primary human colorectal cancer and its overexpression induces aneuploidy

31 March 2020

1 reference

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

31 March 2020

1 reference

Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C

31 March 2020

1 reference

HCP-4, a CENP-C-like protein in Caenorhabditis elegans, is required for resolution of sister centromeres

31 March 2020

1 reference

Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog.

31 March 2020

1 reference

CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells.

31 March 2020

1 reference

CENP-I is essential for centromere function in vertebrate cells

31 March 2020

1 reference

The constitutive centromere component CENP-50 is required for recovery from spindle damage

31 March 2020

1 reference

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

31 March 2020

1 reference

Microtubule polymerization dynamics

31 March 2020

1 reference

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31 March 2020

Identifiers

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30 December 2019

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Consolidated OpenCitations Corpus – April 2017

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