RUNX1 translocations and fusion genes in malignant hemopathies (Q37822736)

23 August 2017

1 reference

title

RUNX1 translocations and fusion genes in malignant hemopathies (English)

1 reference

23 August 2017

6

Marc De Braekeleer

1 reference

23 August 2017

author name string

Etienne De Braekeleer

1

1 reference

23 August 2017

Nathalie Douet-Guilbert

2

1 reference

23 August 2017

Frédéric Morel

3

1 reference

23 August 2017

Marie-Josée Le Bris

4

1 reference

23 August 2017

Claude Férec

5

1 reference

23 August 2017

language of work or name

English

0 references

publication date

1 January 2011

1 reference

23 August 2017

1 reference

23 August 2017

volume

7

1 reference

23 August 2017

issue

1

1 reference

23 August 2017

page(s)

77-91

1 reference

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Oncogenic potential of the RUNX gene family: 'overview'.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Structure and regulated expression of mammalian RUNX genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Core-binding factors in hematopoiesis and immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

The Runt domain identifies a new family of heteromeric transcriptional regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Intrinsic transcriptional activation-inhibition domains of the polyomavirus enhancer binding protein 2/core binding factor alpha subunit revealed in the presence of the beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A large variety of alternatively spliced and differentially expressed mRNAs are encoded by the human acute myeloid leukemia gene AML1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Molecular basis of tissue-specific gene expression mediated by the runt domain transcription factor PEBP2/CBF.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

AML1 interconnected pathways of leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Role of AML1/Runx1 in the pathogenesis of hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Role of the TEL-AML1 fusion gene in the molecular pathogenesis of childhood acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Core-binding factors in haematopoiesis and leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Identification of truncated RUNX1 and RUNX1-PRDM16 fusion transcripts in a case of t(1;21)(p36;q22)-positive therapy-related AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

The EVI1 gene in myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Isolation of a yeast artificial chromosome spanning the 8;21 translocation breakpoint t(8;21)(q22;q22.3) in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

RUNX1-MTG16 fusion gene in acute myeloblastic leukemia with t(16;21)(q24;q22): case report and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Acute myeloid leukemia with t(16;21)(q24;q22) and eosinophilia: case report and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Acute myeloid leukemia associated with variant t(8;21) detected by conventional cytogenetic and molecular studies: a report of four cases and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Insertions generating the 5'RUNX1/3'CBFA2T1 gene in acute myeloid leukemia cases show variable breakpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A child with ALL and ETV6/AML1 fusion on a chromosome 12 due to an insertion of AML1 and loss of ETV6 from the homolog involved in a t(12;15)(p13;q15).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A novel gene, FGA7, is fused to RUNX1/AML1 in a t(4;21)(q28;q22) in a patient with T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

LPXN, a member of the paxillin superfamily, is fused to RUNX1 in an acute myeloid leukemia patient with a t(11;21)(q12;q22) translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

AML1-FOG2 fusion protein in myelodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTHDf2, and ZNF687 in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Molecular mechanisms of leukemogenesis by AML1/EVI-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Human AML1/MDS1/EVI1 fusion protein induces an acute myelogenous leukemia (AML) in mice: a model for human AML

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

AML1 fusion transcripts in t(3;21) positive leukemia: evidence of molecular heterogeneity and usage of splicing sites frequently involved in the generation of normal AML1 transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

E protein silencing by the leukemogenic AML1-ETO fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

The 8;21 translocation in leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Leupaxin is a novel LIM domain protein that forms a complex with PYK2

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Leupaxin negatively regulates B cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Fusion of AML1/Runx1 to copine VIII, a novel member of the copine family, in an aggressive acute myelogenous leukemia with t(12;21) translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

The transcriptional corepressor MTG16a contains a novel nucleolar targeting sequence deranged in t (16; 21)-positive myeloid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

RUNX1 DNA-binding mutations and RUNX1-PRDM16 cryptic fusions in BCR-ABL+ leukemias are frequently associated with secondary trisomy 21 and may contribute to clonal evolution and imatinib resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Two novel translocations disrupt the RUNX1 gene in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Identification of two new translocations that disrupt the AML1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

21q22 balanced chromosome aberrations in therapy-related hematopoietic disorders: report from an international workshop

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A novel translocation, t(9;21)(q13;q22) rearranging the RUNX1 gene in acute myelomonocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Molecular cytogenetic findings in a three-way novel variant of t(1;8;21)(p35;q22;q22): a unique relocation of the AML1/ETO fusion gene 1p35 in AML-M2.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Complex t(8;19;21)(q22;p13;q22) as a sole abnormality in a patient with de novo acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A novel four-way t(6;16;21;8)(p21.3;p11.2;q22;q22) in acute myeloid leukemia with RUNX1/RUNX1T1 rearrangement.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Myelomastocytic leukemia: evidence for the origin of mast cells from the leukemic clone and eradication by allogeneic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Complex t(8;13;21)(q22;q14;q22)--a novel variant of t(8;21) in a patient with acute myeloid leukemia (AML-M2).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Translocation (8;17;15;21)(q22;q23;q15;q22) in acute myeloid leukemia (M2). a four-way variant of t(8;21).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Laboratory study of a complex translocation t(2;8;21) (p12;q22;q22) in a patient with acute myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Complex translocation (8;12;21): a new variant of t(8;21) in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

t(8;21;14)(q22;q22;q24) is a novel variant of t(8;21) with chimeric transcripts of AML1-ETO in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Identification of chromosome changes in acute myeloid leukemia (AML-M2) by molecular cytogenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A variant t(8;10;21) in a patient with pathological features mimicking atypical chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

A Complex Variant T(8;21) Involving Chromosome 3 in a Child with Acute Myeloblastic Leukemia with Eosinophilia (AML M4Eo)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Comparison of karyotype analysis and RT-PCR for AML1/ETO in 204 unselected patients with AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Simple variant t(8;21) acute myeloid leukemias harbor insertions of the AML1 or ETO genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Submicroscopic deletions in an acute myeloid leukemia case with a four-way t(8;11;16;21)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

Fluorescence In Situ Hybridization Analysis of Masked (8;21)(q22;q22) Translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.10.158

21 January 2018

Identifiers

DOI

10.2217/FON.10.158

1 reference

23 August 2017

1 reference