Microglia: key innate immune cells of the brain (Q37809665)

23 August 2017

Microglia: key innate immune cells of the brain (English)

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23 August 2017

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Julia Kofler

1

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PubMed ID

21078923

23 August 2017

Clayton A Wiley

series ordinal

2

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PubMed ID

21078923

23 August 2017

language of work or name

English

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publication date

15 November 2010

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23 August 2017

Toxicologic Pathology

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23 August 2017

39

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23 August 2017

103-114

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23 August 2017

1

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The amino-terminally truncated forms of amyloid beta-protein in brain macrophages in the ischemic lesions of Alzheimer's disease patients.

23 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Specificity of mechanisms for plaque removal after A beta immunotherapy for Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Toll-like receptors in defense and damage of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

The microglial cell. A historical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Neurogenic niche modulation by activated microglia: transforming growth factor beta increases neurogenesis in the adult dentate gyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglial control of neuronal death and synaptic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

The role of the immune system in clearance of Abeta from the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

In-vivo measurement of activated microglia in dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

In vivo visualization of activated glia by [11C] (R)-PK11195-PET following herpes encephalitis reveals projected neuronal damage beyond the primary focal lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

The origin and cell lineage of microglia: new concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

ATP mediates rapid microglial response to local brain injury in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Evidence that aging and amyloid promote microglial cell senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Development of monocytes, macrophages, and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Alternative activation of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

The macrophage: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Alternative activation of macrophages: mechanism and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Down-regulation of the macrophage lineage through interaction with OX2 (CD200)

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

The mononuclear phagocyte system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglial response to gold nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Downregulation of macrophage inhibitory molecules in multiple sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Proliferating resident microglia express the stem cell antigen CD34 in response to acute neural injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

The function of microglia, either neuroprotection or neurotoxicity, is determined by the equilibrium among factors released from activated microglia in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglia promote the death of developing Purkinje cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Alternative activation of macrophages: an immunologic functional perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Pathogen recognition and inflammatory signaling in innate immune defenses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Exploring the full spectrum of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Regeneration of entorhinal fibers in mouse slice cultures is age dependent and can be stimulated by NT-4, GDNF, and modulators of G-proteins and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglial physiology: unique stimuli, specialized responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Decline of immune responsiveness: a pathogenetic factor in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglial phenotype: is the commitment reversible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Bone-marrow-derived microglia: myth or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglia and Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Pattern recognition receptors and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Evidence for synaptic stripping by cortical microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

PET imaging of brain macrophages using the peripheral benzodiazepine receptor in a macaque model of neuroAIDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds to activated and infected brain macrophages in areas of synaptic degeneration: implications for PET imaging of neuroinflammation in lentiviral encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Imaging microglial activation during neuroinflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglia instruct subventricular zone neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

CD200-CD200R regulation of microglia activation in the pathogenesis of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Immunology and immunotherapy of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Positron emission tomography imaging of peripheral benzodiazepine receptor binding in human immunodeficiency virus-infected subjects with and without cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Phagocytosis of ?/A4 amyloid fibrils of the neuritic neocortical plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

Immunotherapy for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623310387619

21 January 2018

Identifiers

DOI

10.1177/0192623310387619

1 reference

23 August 2017

1 reference

PubMed ID

21078923