Lung epithelial wound healing in health and disease (Q37798031)

23 August 2017

Lung epithelial wound healing in health and disease (English)

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23 August 2017

1 reference

Aaron Gardner

1

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PubMed ID

20923342

23 August 2017

Lee A Borthwick

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2

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PubMed ID

20923342

23 August 2017

Andrew J Fisher

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3

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23 August 2017

1 October 2010

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Expert Review of Respiratory Medicine

23 August 2017

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23 August 2017

4

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23 August 2017

5

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23 August 2017

647-660

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Defensins: key players or bystanders in infection, injury, and repair in the lung?

23 August 2017

1 reference

The role of epithelial beta-defensins and cathelicidins in host defense of the lung

21 January 2018

1 reference

Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity.

21 January 2018

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Plasma-derived proteins in airway defence, disease and repair of epithelial injury.

21 January 2018

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Simulation of lung alveolar epithelial wound healing in vitro

21 January 2018

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Regulators of endothelial and epithelial barrier integrity and function in acute lung injury

21 January 2018

1 reference

The airway epithelium is central to the pathogenesis of asthma

21 January 2018

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The disruption of the epithelial mesenchymal trophic unit in COPD.

21 January 2018

1 reference

Quantitative determination of EGF-R during epidermal wound healing

21 January 2018

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Soluble TNF mediates the transition from pulmonary inflammation to fibrosis

21 January 2018

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Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis

21 January 2018

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Epithelial repair mechanisms in the lung

21 January 2018

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The role of transforming growth factor beta in lung development and disease

21 January 2018

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Induction of epithelial-mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-beta1.

21 January 2018

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Transforming growth factor-beta signaling across ages: from distorted lung development to chronic obstructive pulmonary disease

21 January 2018

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The regulation of TGFbeta signal transduction

21 January 2018

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Metalloproteinases and their inhibitors: regulators of wound healing

21 January 2018

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Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

21 January 2018

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The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity

21 January 2018

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Progress in matrix metalloproteinase research

21 January 2018

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Time course of lung parenchyma remodeling in pulmonary and extrapulmonary acute lung injury.

21 January 2018

1 reference

Wound closure: evidence of cooperation between fibroblasts and collagen matrix

21 January 2018

1 reference

Treating IPF--all or nothing? A PRO-CON debate

21 January 2018

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IPF: new insight on pathogenesis and treatment

21 January 2018

1 reference

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

21 January 2018

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TGF-beta, Smad3 and the process of progressive fibrosis.

21 January 2018

1 reference

Inflammation and epithelial to mesenchymal transition in lung transplant recipients: role in dysregulated epithelial wound repair

21 January 2018

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Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation.

21 January 2018

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Transforming growth factor type beta induces monocyte chemotaxis and growth factor production

21 January 2018

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Enhanced survival of lung granulocytes in an animal model of asthma: evidence for a role of GM-CSF activated STAT5 signalling pathway

21 January 2018

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Differential adhesion of Pseudomonas aeruginosa to human respiratory epithelial cells in primary culture

21 January 2018

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Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts

21 January 2018

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Alternative activation of macrophages

21 January 2018

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Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss

21 January 2018

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Identification of the haemoglobin scavenger receptor.

21 January 2018

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Other functions, other genes: alternative activation of antigen-presenting cells

21 January 2018

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Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells.

21 January 2018

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

21 January 2018

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Current and emerging drugs for idiopathic pulmonary fibrosis

21 January 2018

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Association of TNF polymorphisms with sarcoidosis, its prognosis and tumour necrosis factor (TNF)-alpha levels in Asian Indians

21 January 2018

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Cytokine gene polymorphisms in idiopathic pulmonary fibrosis.

21 January 2018

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Interstitial fibrosis and growth factors

21 January 2018

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Roles for insulin-like growth factor I and transforming growth factor-beta in fibrotic lung disease

21 January 2018

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Alpha-smooth muscle actin expression upregulates fibroblast contractile activity

21 January 2018

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Circulating fibrocytes: collagen-secreting cells of the peripheral blood

21 January 2018

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Fibrocyte localization to the airway smooth muscle is a feature of asthma

21 January 2018

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Epithelial cells and fibroblasts: structural repair and remodelling in the airways.

21 January 2018

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Myofibroblasts and mechano-regulation of connective tissue remodelling

21 January 2018

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An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis

21 January 2018

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Formation and function of the myofibroblast during tissue repair

21 January 2018

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Thrombin differentiates normal lung fibroblasts to a myofibroblast phenotype via the proteolytically activated receptor-1 and a protein kinase C-dependent pathway

21 January 2018

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Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing

21 January 2018

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Impaired wound contraction in stromelysin-1-deficient mice

21 January 2018

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Mechanisms of force generation and transmission by myofibroblasts

21 January 2018

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Wound splinting regulates granulation tissue survival

21 January 2018

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Intercellular adhesion, signalling and the cytoskeleton

21 January 2018

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Fibroblast foci are not discrete sites of lung injury or repair: the fibroblast reticulum

21 January 2018

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Pak1 and PIX regulate contact inhibition during epithelial wound healing

21 January 2018

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Remodeling epithelial cell organization: transitions between front-rear and apical-basal polarity

21 January 2018

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Two distinct modes of guidance signalling during collective migration of border cells

21 January 2018

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Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

21 January 2018

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Multiple rows of cells behind an epithelial wound edge extend cryptic lamellipodia to collectively drive cell-sheet movement

21 January 2018

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Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength

21 January 2018

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Filopodia: molecular architecture and cellular functions

21 January 2018

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Life at the leading edge: the formation of cell protrusions

21 January 2018

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Rho GTPases control polarity, protrusion, and adhesion during cell movement

21 January 2018

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

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The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis

21 January 2018

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The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1

21 January 2018

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Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway

21 January 2018

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Assessing the reproducibility of asthma candidate gene associations, using genome-wide data

21 January 2018

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Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling.

21 January 2018

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Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial

21 January 2018

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Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases mRNA transcripts in the bronchial secretions of asthmatics.

21 January 2018

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Remodeling associated expression of matrix metalloproteinase 9 but not tissue inhibitor of metalloproteinase 1 in airway epithelium: modulation by immunostimulatory DNA.

21 January 2018

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Expression of matrix metalloproteinases MMP-9 within the airways in asthma

21 January 2018

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Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma

21 January 2018

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Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium

21 January 2018

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Matrilysin expression and function in airway epithelium

21 January 2018

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Tissue inhibitor of metalloproteinase-1 moderates airway re-epithelialization by regulating matrilysin activity

21 January 2018

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Tissue inhibitor of metalloproteinase-1 deficiency abrogates obliterative airway disease after heterotopic tracheal transplantation

21 January 2018

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Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds

21 January 2018

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Mechanical stretch decreases migration of alveolar epithelial cells through mechanisms involving Rac1 and Tiam1.

21 January 2018

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Basal cells as stem cells of the mouse trachea and human airway epithelium

21 January 2018

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Maintenance and repair of the bronchiolar epithelium

21 January 2018

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Mice lacking uteroglobin are highly susceptible to developing pulmonary fibrosis.

21 January 2018

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Epithelial-mesenchymal transitions in development and disease

21 January 2018

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TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease

21 January 2018

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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

21 January 2018

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Localization of type IV collagen, laminin, heparan sulfate proteoglycan, and fibronectin to the basal lamina of basement membranes

21 January 2018

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The myofibroblast in wound healing and fibrocontractive diseases

21 January 2018

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Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in the respiratory tract: potential implications in asthma and other lung diseases

21 January 2018

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Regulation of wound healing from a connective tissue perspective

21 January 2018

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Expression analysis of angiogenic growth factors and biological axis CXCL12/CXCR4 axis in idiopathic pulmonary fibrosis.

21 January 2018

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Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis

21 January 2018

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The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts.

21 January 2018

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Ex Vivo Metrics, a preclinical tool in new drug development

21 January 2018

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Use of a three-dimensional cell culture model to study airway smooth muscle-mast cell interactions in airway remodeling

21 January 2018

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Keratinocyte growth factor promotes cell motility during alveolar epithelial repair in vitro

21 January 2018

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Integrin β3 genotype influences asthma and allergy phenotypes in the first 6 years of life

21 January 2018

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Fibroblast traction as a mechanism for collagen morphogenesis

21 January 2018

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Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERS.10.62

1 reference

23 August 2017

1 reference

PubMed ID

20923342