Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis (Q28587589)

31 January 2017

title

Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis (English)

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ERBB receptor feedback inhibitor 1

31 January 2017

main subject

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GOA release 2020-03-11

4

Ignacio Wistuba

1 reference

31 January 2017

Nili Jin

1

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31 January 2017

Sung-Nam Cho

2

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31 January 2017

M. Gabriela Raso

3

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31 January 2017

Yvonne Smith

5

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31 January 2017

Yanan Yang

6

1 reference

31 January 2017

Jonathan M. Kurie

7

1 reference

31 January 2017

Rudolph Yen

8

1 reference

31 January 2017

Christopher M. Evans

9

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31 January 2017

Thomas Ludwig

10

1 reference

31 January 2017

Jae-Wook Jeong

11

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31 January 2017

Francesco J. DeMayo

12

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31 January 2017

language of work or name

English

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publication date

1 October 2009

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31 January 2017

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31 January 2017

volume

136

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31 January 2017

issue

19

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31 January 2017

page(s)

3347–3356

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Vascular endothelial growth factor-dependent and -independent regulation of angiogenesis

31 January 2017

cites work

1 reference

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Mig-6, signal transduction, stress response and cancer

17 March 2017

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Stretch-activated signaling pathways responsible for early response gene expression in fetal lung epithelial cells

17 March 2017

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Evidence that MIG-6 is a tumor-suppressor gene

17 March 2017

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Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation

17 March 2017

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Targeted expression of RALT in mouse skin inhibits epidermal growth factor receptor signalling and generates a Waved-like phenotype.

17 March 2017

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Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin

17 March 2017

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Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

17 March 2017

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Feedback inhibition by RALT controls signal output by the ErbB network

17 March 2017

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Mig-6 is a negative regulator of the epidermal growth factor receptor signal

17 March 2017

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17 March 2017

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Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stre

17 March 2017

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Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

17 March 2017

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Identification of a novel mitogen-inducible gene (mig-6): regulation during G1 progression and differentiation

17 March 2017

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Epidermal growth factor-related peptides and their receptors in human malignancies

17 March 2017

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Vascular endothelial growth factor is a secreted angiogenic mitogen

17 March 2017

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Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease

17 March 2017

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Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system

29 September 2017

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Lung development and adult lung diseases

29 September 2017

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IL-1beta disrupts postnatal lung morphogenesis in the mouse

29 September 2017

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Pulmonary outcomes in bronchopulmonary dysplasia

29 September 2017

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Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes

29 September 2017

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Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth

29 September 2017

1 reference

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Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease

29 September 2017

1 reference

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Autocrine, paracrine and juxtacrine signaling by EGFR ligands

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Gene 33 inhibits apoptosis of breast cancer cells and increases poly(ADP-ribose) polymerase expression

29 September 2017

1 reference

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Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes

29 September 2017

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Pathology of new bronchopulmonary dysplasia

29 September 2017

1 reference

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Transcription factors in mouse lung development and function

29 September 2017

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The molecular basis of lung morphogenesis

29 September 2017

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14-3-3 proteins block apoptosis and differentially regulate MAPK cascades

29 September 2017

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Molecular mechanisms controlling lung morphogenesis

29 September 2017

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Respiratory epithelial cell expression of human transforming growth factor-alpha induces lung fibrosis in transgenic mice

29 September 2017

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Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology

29 September 2017

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The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

29 September 2017

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Conditional deletion of Pten causes bronchiolar hyperplasia

29 September 2017

1 reference

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Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.

3 June 2018

1 reference

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Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Impaired lung branching morphogenesis in the absence of functional EGF receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Generation of a Mig-6 conditional null allele.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Epithelial-vascular cross talk mediated by VEGF-A and HGF signaling directs primary septae formation during distal lung morphogenesis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Sprouty2 downregulation plays a pivotal role in mediating crosstalk between TGF-beta1 signaling and EGF as well as FGF receptor tyrosine kinase-ERK pathways in mesenchymal cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Loss of PECAM-1 function impairs alveolarization.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Transient induction of TGF-alpha disrupts lung morphogenesis, causing pulmonary disease in adulthood.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Role of 14-3-3-mediated p38 mitogen-activated protein kinase inhibition in cardiac myocyte survival

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Embryonic testis cord formation and mesonephric cell migration requires the phosphotidylinositol 3-kinase signaling pathway

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Do lung remodeling, repair, and regeneration recapitulate respiratory ontogeny?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Disrupted pulmonary vasculature and decreased vascular endothelial growth factor, Flt-1, and TIE-2 in human infants dying with bronchopulmonary dysplasia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Endothelial monocyte activating polypeptide II inhibits lung neovascularization and airway epithelial morphogenesis.

27 November 2018

1 reference

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Manipulation of the angiopoietic/hemangiopoietic commitment in the avian embryo.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Synergistic induction of gene 33 expression by retinoic acid and insulin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2739148

Growth and development of the lung

27 November 2018

1 reference

12 December 2020

Molecular cloning of cDNAs cognate to genes sensitive to hormonal control in rat liver

1 reference

12 December 2020

Reciprocal regulation of gene transcription by insulin. Inhibition of the phosphoenolpyruvate carboxykinase gene and stimulation of gene 33 in a single cell type

1 reference

12 December 2020

Immunocytochemical localization of epidermal growth factor in the developing human respiratory system and in acute and chronic lung disease in the neonate

1 reference

12 December 2020

Strain-dependent epithelial defects in mice lacking the EGF receptor

1 reference

12 December 2020

Immunolocalization of transforming growth factor-alpha, epidermal growth factor (EGF), and EGF-receptor in normal and injured developing human lung

1 reference

12 December 2020

H441 pulmonary epithelial cell mitogenic effects and signaling pathways in response to HGF and TGF-alpha

1 reference

12 December 2020

VEGF enhances pulmonary vasculogenesis and disrupts lung morphogenesis in vivo

1 reference

12 December 2020

Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer

1 reference

12 December 2020

Distribution of ERK1/2 and ERK3 during normal rat fetal lung development

1 reference

12 December 2020

Pulmonary vascular endothelial growth factor and Flt-1 in fetuses, in acute and chronic lung disease, and in persistent pulmonary hypertension of the newborn

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.032979

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