What's new in asthma pathophysiology and immunopathology? (Q37798030)

23 August 2017

What's new in asthma pathophysiology and immunopathology? (English)

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23 August 2017

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Vidyanand Anaparti

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author name string

Kanami Orihara

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1

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PubMed ID

20923340

23 August 2017

Nyla Dil

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2

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PubMed ID

20923340

23 August 2017

Redwan Moqbel

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4

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23 August 2017

1 October 2010

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Expert Review of Respiratory Medicine

23 August 2017

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23 August 2017

4

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23 August 2017

605-629

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23 August 2017

5

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Division of labor between dendritic cell subsets of the lung

23 August 2017

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Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation

21 January 2018

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Studying the function of dendritic cells in mouse models of asthma.

21 January 2018

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Uptake of apoptotic DC converts immature DC into tolerogenic DC that induce differentiation of Foxp3+ Treg

21 January 2018

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Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma

21 January 2018

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Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand

21 January 2018

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Cathepsins and compartmentalization in antigen presentation

21 January 2018

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Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation

21 January 2018

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Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases.

21 January 2018

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Chemokines and their receptors in allergic disease

21 January 2018

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Essential role of dendritic cell CD80/CD86 costimulation in the induction, but not reactivation, of TH2 effector responses in a mouse model of asthma.

21 January 2018

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Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus

21 January 2018

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Biology of lung dendritic cells at the origin of asthma

21 January 2018

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Asthma and allergic symptoms in relation to house dust endotoxin: Phase Two of the International Study on Asthma and Allergies in Childhood (ISAAC II).

21 January 2018

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Heterogeneity of human effector CD4+ T cells.

21 January 2018

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Regulation of the T cell response

21 January 2018

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Asthma onset prior to multiple sclerosis and the contribution of sibling exposure in early life

21 January 2018

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Selective deregulation in chemokine signaling pathways of CD4+CD25(hi)CD127(lo)/(-) regulatory T cells in human allergic asthma

21 January 2018

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Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease

21 January 2018

1 reference

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

21 January 2018

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Oral tolerance in the absence of naturally occurring Tregs

21 January 2018

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Mechanisms and treatment of allergic disease in the big picture of regulatory T cells

21 January 2018

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Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells

21 January 2018

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Regulatory T cells in many flavors control asthma

21 January 2018

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T-cell regulatory mechanisms in specific immunotherapy

21 January 2018

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Anergic cells generated by blocking CD28 and CD40 costimulatory pathways in vitro ameliorate collagen induced arthritis.

21 January 2018

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CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction.

21 January 2018

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Indoleamine 2,3-dioxygenase and tumor-induced tolerance

21 January 2018

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Role of regulatory T cells and FOXP3 in human diseases.

21 January 2018

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

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21 January 2018

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IL-17A augments TNF-alpha-induced IL-6 expression in airway smooth muscle by enhancing mRNA stability.

21 January 2018

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Airway remodeling-associated mediators in moderate to severe asthma: effect of steroids on TGF-beta, IL-11, IL-17, and type I and type III collagen expression

21 January 2018

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Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease.

21 January 2018

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Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge

21 January 2018

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Involvement of human natural killer cells in asthma pathogenesis: natural killer 2 cells in type 2 cytokine predominance.

21 January 2018

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Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice

21 January 2018

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Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice

21 January 2018

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IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells

21 January 2018

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Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17

21 January 2018

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Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

21 January 2018

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Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB.

21 January 2018

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Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells

21 January 2018

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Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population

21 January 2018

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Bronchoalveolar lavage invariant natural killer T cells are not increased in asthma

21 January 2018

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Natural killer T cells in the lungs of patients with asthma

21 January 2018

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The rise of the phoenix: the expanding role of the eosinophil in health and disease

21 January 2018

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Eosinophil function in allergic inflammation: from bone marrow to tissue response

21 January 2018

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The role of eosinophils in the pathogenesis of asthma

21 January 2018

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Eosinophils: biological properties and role in health and disease.

21 January 2018

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Allergen-induced fluctuation in CC chemokine receptor 3 expression on bone marrow CD34+ cells from asthmatic subjects: significance for mobilization of haemopoietic progenitor cells in allergic inflammation

21 January 2018

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Divergence of mechanisms regulating respiratory burst in blood and sputum eosinophils and neutrophils from atopic subjects

21 January 2018

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Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

21 January 2018

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Mepolizumab and exacerbations of refractory eosinophilic asthma

21 January 2018

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Defining a link with asthma in mice congenitally deficient in eosinophils.

21 January 2018

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21 January 2018

Immunobiology of asthma

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Tissue remodeling and angiogenesis in asthma: the role of the eosinophil

21 January 2018

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TGF-beta, eosinophils and IL-13 in allergic airway remodeling: a critical appraisal with therapeutic considerations

21 January 2018

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Immunologic and inflammatory mechanisms that drive asthma progression to remodeling

21 January 2018

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A critical role for eosinophils in allergic airways remodeling.

21 January 2018

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Lymph node trafficking and antigen presentation by endobronchial eosinophils

21 January 2018

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Eotaxin is required for the baseline level of tissue eosinophils

21 January 2018

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Thymic indoleamine 2,3-dioxygenase-positive eosinophils in young children: potential role in maturation of the naive immune system

21 January 2018

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T cell apoptosis by tryptophan catabolism

21 January 2018

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Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes

21 January 2018

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Allergic pulmonary inflammation in mice is dependent on eosinophil-induced recruitment of effector T cells

21 January 2018

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Eosinophils in health and disease: the LIAR hypothesis

21 January 2018

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Non-eosinophilic asthma: importance and possible mechanisms

21 January 2018

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Heterogeneity of airway inflammation in persistent asthma : evidence of neutrophilic inflammation and increased sputum interleukin-8.

21 January 2018

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Relationship between airway inflammation, hyperresponsiveness, and obstruction in asthma

21 January 2018

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Expression of pulmonary lactoferrin in sudden-onset and slow-onset asthma with fatal outcome.

21 January 2018

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Steroid-unresponsive asthma

21 January 2018

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Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

21 January 2018

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Oral corticosteroids decrease eosinophil and CC chemokine expression but increase neutrophil, IL-8, and IFN-gamma-inducible protein 10 expression in asthmatic airway mucosa

21 January 2018

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Images in allergy and immunology: neutrophils in asthma

21 January 2018

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Is the neutrophil the key effector cell in severe asthma?

21 January 2018

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IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

21 January 2018

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IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines

21 January 2018

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T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma.

21 January 2018

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Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine

21 January 2018

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Eosinophil trans-basement membrane migration induced by interleukin-8 and neutrophils.

21 January 2018

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Mast cells in the promotion and limitation of chronic inflammation.

21 January 2018

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Immunomodulatory mast cells: negative, as well as positive, regulators of immunity

21 January 2018

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New developments in mast cell biology

21 January 2018

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Ultrastructure of bronchial biopsies from patients with allergic and non-allergic asthma

21 January 2018

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The role of the mast cell in the pathophysiology of asthma

21 January 2018

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FcepsilonRI-mediated amphiregulin production by human mast cells increases mucin gene expression in epithelial cells.

21 January 2018

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Mast cells express IL-17A in rheumatoid arthritis synovium

21 January 2018

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Role of mast cells in airway remodeling

21 January 2018

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Activation of human mast cells through the platelet-activating factor receptor

21 January 2018

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Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity

21 January 2018

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Mast cells are essential intermediaries in regulatory T-cell tolerance

21 January 2018

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Mast cells: makers and breakers of allergic inflammation

21 January 2018

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New insights into the roles for basophils in acute and chronic allergy

21 January 2018

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Basophils beyond effector cells of allergic inflammation

21 January 2018

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Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils

21 January 2018

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Human basophils secrete IL-3: evidence of autocrine priming for phenotypic and functional responses in allergic disease

21 January 2018

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Role of basophils in the initiation of Th2 responses

21 January 2018

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Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis

21 January 2018

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Human basophils as effectors and immunomodulators of allergic inflammation and innate immunity

21 January 2018

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Controversy surrounding the increased expression of TGF beta 1 in asthma

21 January 2018

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Remodeling in asthma and chronic obstructive pulmonary disease

21 January 2018

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Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-beta

21 January 2018

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Effects of a low-molecular-weight CCR-3 antagonist on chronic experimental asthma.

21 January 2018

1 reference

The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts

21 January 2018

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Essential role of nitric oxide in VEGF-induced, asthma-like angiogenic, inflammatory, mucus, and physiologic responses in the lung

21 January 2018

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Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack

21 January 2018

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Airway epithelial cells in asthma

21 January 2018

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Epithelium dysfunction in asthma

21 January 2018

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The airway epithelium is central to the pathogenesis of asthma

21 January 2018

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Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced bronchoconstriction

21 January 2018

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Beyond inflammation: airway epithelial cells are at the interface of innate and adaptive immunity

21 January 2018

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Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells

21 January 2018

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beta2-Adrenoceptor agonists enhance cytokine-induced release of thymic stromal lymphopoietin by lung tissue cells

21 January 2018

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Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25.

21 January 2018

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Increased IL-33 expression by epithelial cells in bronchial asthma.

21 January 2018

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Epithelial cell proliferation contributes to airway remodeling in severe asthma

21 January 2018

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Altered protein tyrosine phosphorylation in asthmatic bronchial epithelium

21 January 2018

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The role of the epithelium in airway remodeling in asthma.

21 January 2018

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Acute exacerbations of asthma: epidemiology, biology and the exacerbation-prone phenotype

21 January 2018

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Advances in mucous cell metaplasia: a plug for mucus as a therapeutic focus in chronic airway disease

21 January 2018

1 reference

Respiratory tract mucin genes and mucin glycoproteins in health and disease

21 January 2018

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Pranlukast inhibits NF-kappaB activation and MUC2 gene expression in cultured human epithelial cells

21 January 2018

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Posttransplant bronchiolitis obliterans syndrome is associated with bronchial epithelial to mesenchymal transition.

21 January 2018

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Induction of epithelial-mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-beta1.

21 January 2018

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Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium

21 January 2018

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Relationship of airway wall thickening to an imbalance between matrix metalloproteinase-9 and its inhibitor in asthma

21 January 2018

1 reference

Airway smooth muscle: a modulator of airway remodeling in asthma

21 January 2018

1 reference

Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling

21 January 2018

1 reference

Calcium signaling in airway smooth muscle

21 January 2018

1 reference

Inflammation of bronchial smooth muscle in allergic asthma

21 January 2018

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The extracellular deposition of mast cell products is increased in hypertrophic airways smooth muscles in allergic asthma but not in nonallergic asthma.

21 January 2018

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Increased expression of IL-33 in severe asthma: evidence of expression by airway smooth muscle cells

21 January 2018

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ADAM33 expression in asthmatic airways and human embryonic lungs

21 January 2018

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Airway structural components drive airway smooth muscle remodeling in asthma

21 January 2018

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Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration

21 January 2018

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Reversal of allergen-induced airway remodeling by CysLT1 receptor blockade

21 January 2018

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Use of a three-dimensional cell culture model to study airway smooth muscle-mast cell interactions in airway remodeling

21 January 2018

1 reference

Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function

21 January 2018

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FGF2 in asthmatic airway-smooth-muscle-cell hyperplasia

21 January 2018

1 reference

Airway smooth muscle chemokine receptor expression and function in asthma

21 January 2018

1 reference

Airway smooth muscle hyperplasia and hypertrophy correlate with glycogen synthase kinase-3(beta) phosphorylation in a mouse model of asthma

21 January 2018

1 reference

Gene expression in asthmatic airway smooth muscle

21 January 2018

1 reference

Epithelial-mesenchymal interactions in pulmonary fibrosis

21 January 2018

1 reference

Expression of transforming growth factor-beta (TGF-beta) in chronic idiopathic cough

21 January 2018

1 reference

TGF-beta: its role in asthma and therapeutic potential

21 January 2018

1 reference

Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma

21 January 2018

1 reference

TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids.

21 January 2018

1 reference

Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling

21 January 2018

1 reference

Vascular endothelial growth factor as a non-invasive marker of pulmonary vascular remodeling in patients with bronchitis-type of COPD.

21 January 2018

1 reference

Relationship between exhaled nitric oxide measured by two offline methods and bronchial hyperresponsiveness in Japanese adults with asthma.

21 January 2018

1 reference

Augmented epithelial endothelin-1 expression in refractory asthma

21 January 2018

1 reference

Clinical implications for vascular endothelial growth factor in the lung: friend or foe?

21 January 2018

1 reference

Tissue-engineered endothelial and epithelial implants differentially and synergistically regulate airway repair

21 January 2018

1 reference

Vascular endothelial growth factor of the lung: friend or foe

21 January 2018

1 reference

Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis

21 January 2018

1 reference

The role of eosinophil major basic protein in angiogenesis

21 January 2018

1 reference

Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions

21 January 2018

1 reference

Effects of inhaled fluticasone on angiogenesis and vascular endothelial growth factor in asthma

21 January 2018

1 reference

Corticosteroid enhances TNF-alpha-mediated leukocyte adhesion to pulmonary microvascular endothelial cells

21 January 2018

1 reference

Kynurenine is an endothelium-derived relaxing factor produced during inflammation

21 January 2018

1 reference

Tryptophan catabolites regulate mucosal sensitization to ovalbumin in respiratory airways

21 January 2018

1 reference

Thymic stromal lymphopoietin

21 January 2018

1 reference

Sensing the outside world: TSLP regulates barrier immunity.

21 January 2018

1 reference

Structure and signalling in the IL-17 receptor family

21 January 2018

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The roles of IL-17A in inflammatory immune responses and host defense against pathogens

21 January 2018

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

21 January 2018

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Regulation of inflammatory responses by IL-17F

21 January 2018

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Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells

21 January 2018

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A role for TSLP in the development of inflammation in an asthma model

21 January 2018

1 reference

TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand.

21 January 2018

1 reference

Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease

21 January 2018

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Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice

21 January 2018

1 reference

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

21 January 2018

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Disease-associated functions of IL-33: the new kid in the IL-1 family

21 January 2018

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IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals

21 January 2018

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Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils

21 January 2018

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A novel IL-1 family cytokine, IL-33, potently activates human eosinophils

21 January 2018

1 reference

ST2 gene induced by type 2 helper T cell (Th2) and proinflammatory cytokine stimuli may modulate lung injury and fibrosis

21 January 2018

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IL-33-activated dendritic cells induce an atypical TH2-type response

21 January 2018

1 reference

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

21 January 2018

1 reference

Immunological and inflammatory functions of the interleukin-1 family

21 January 2018

1 reference

The IL-1 family: regulators of immunity

21 January 2018

1 reference

21 January 2018

Th9 and allergic disease

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Decreased hyaluronan in airway smooth muscle cells from patients with asthma and COPD.

21 January 2018

1 reference

Indirect evidence of bronchial inflammation assessed by titration of inflammatory mediators in BAL fluid of patients with asthma

21 January 2018

1 reference

Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma

21 January 2018

1 reference

The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases

21 January 2018

1 reference

Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma

21 January 2018

1 reference

A chitinase-like protein in the lung and circulation of patients with severe asthma

21 January 2018

1 reference

Infections and allergy - helminths, hygiene and host immune regulation

21 January 2018

1 reference

Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies.

21 January 2018

1 reference

Acidic mammalian chitinase regulates epithelial cell apoptosis via a chitinolytic-independent mechanism

21 January 2018

1 reference

Role of breast regression protein-39/YKL-40 in asthma and allergic responses

21 January 2018

1 reference

Demethylallosamidin, a chitinase inhibitor, suppresses airway inflammation and hyperresponsiveness

21 January 2018

1 reference

Chitin induces accumulation in tissue of innate immune cells associated with allergy

21 January 2018

1 reference

Global strategy for asthma management and prevention: GINA executive summary.

21 January 2018

1 reference

Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma.

21 January 2018

1 reference

Effects of steroid therapy on inflammatory cell subtypes in asthma

21 January 2018

1 reference

The definition and diagnosis of asthma

21 January 2018

1 reference

Quantitative sputum cell counts as a marker of airway inflammation in clinical practice

21 January 2018

1 reference

The utility of sputum eosinophils and exhaled nitric oxide for monitoring asthma control with special attention to childhood asthma

21 January 2018

1 reference

Inhaled corticosteroids as combination therapy with beta-adrenergic agonists in airways disease: present and future.

21 January 2018

1 reference

Side effects with inhaled corticosteroids: the physician's perception

21 January 2018

1 reference

21 January 2018

New therapies for asthma

1 reference

Meta analysis: Increased risk of asthma death with salmeterol monotherapy compared with placebo, but not with salmeterol plus inhaled corticosteroids compared with inhaled corticosteroids alone

21 January 2018

1 reference

Systems biology: new approaches to old environmental health problems

21 January 2018

1 reference

Metabolomic biomarkers in a model of asthma exacerbation: urine nuclear magnetic resonance

21 January 2018

1 reference

Asthma, the ugly duckling of lung disease proteomics?

21 January 2018

1 reference

Proteomics: is it an approach to understand the progression of chronic lung disorders?

21 January 2018

1 reference

Recent development in genomic and proteomic research for asthma

21 January 2018

1 reference

Effects of cysteinyl leukotrienes and leukotriene receptor antagonists on markers of inflammation

21 January 2018

1 reference

Leukotriene modifiers in the treatment of asthma in children

21 January 2018

1 reference

Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report.

21 January 2018

1 reference

Protection of leukotriene receptor antagonist against aspirin-induced bronchospasm in asthmatics

21 January 2018

1 reference

The effect of montelukast on eosinophil apoptosis: induced sputum findings of patients with mild persistent asthma.

21 January 2018

1 reference

Asthma exacerbations . 4: Prevention

21 January 2018

1 reference

Efficacy of leukotriene receptor antagonists and synthesis inhibitors in asthma.

21 January 2018

1 reference

IgE expression pattern in lung: relation to systemic IgE and asthma phenotypes.

21 January 2018

1 reference

AllerHunter: a SVM-pairwise system for assessment of allergenicity and allergic cross-reactivity in proteins

21 January 2018

1 reference

Local isotype switching to IgE in airway mucosa

21 January 2018

1 reference

Germinal-centre reactions in allergic inflammation

21 January 2018

1 reference

Local release of B cell-activating factor of the TNF family after segmental allergen challenge of allergic subjects

21 January 2018

1 reference

The role of APRIL and BAFF in lymphocyte activation

21 January 2018

1 reference

B cells and aging: molecules and mechanisms

21 January 2018

1 reference

B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling

21 January 2018

1 reference

Triggers of IgE class switching and allergy development

21 January 2018

1 reference

Effects of omalizumab on markers of inflammation in patients with allergic asthma

21 January 2018

1 reference

12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels

21 January 2018

1 reference

Mucosal immunity in asthma and chronic obstructive pulmonary disease: a role for immunoglobulin A?

21 January 2018

1 reference

In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure

21 January 2018

1 reference

Distinct regulation of IgE, IgG4 and IgA by T regulatory cells and toll-like receptors

21 January 2018

1 reference

Immune tolerance in allergy

21 January 2018

1 reference

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

21 January 2018

1 reference

Impact of sublingual immunotherapy on specific antibody levels in asthmatic children allergic to house dust mites

21 January 2018

1 reference

Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology

21 January 2018

1 reference

Immunomodulator therapy: monoclonal antibodies, fusion proteins, cytokines, and immunoglobulins

21 January 2018

1 reference

Biologic therapies for asthma

21 January 2018

1 reference

Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities

21 January 2018

1 reference

Effect of omalizumab treatment on peripheral eosinophil and T-lymphocyte function in patients with allergic asthma.

21 January 2018

1 reference

Severe asthma and the omalizumab option.

21 January 2018

1 reference

Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab).

21 January 2018

1 reference

Omalizumab: not only for asthma

21 January 2018

1 reference

Importance of cytokines in murine allergic airway disease and human asthma

21 January 2018

1 reference

Mepolizumab and eosinophil-mediated disease

21 January 2018

1 reference

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

21 January 2018

1 reference

The trials and tribulations of IL-5, eosinophils, and allergic asthma

21 January 2018

1 reference

Anti-IL-5 (mepolizumab) therapy reduces eosinophil activation ex vivo and increases IL-5 and IL-5 receptor levels

21 January 2018

1 reference

Targeting TNF-alpha: a novel therapeutic approach for asthma

21 January 2018

1 reference

Evidence of a role of tumor necrosis factor alpha in refractory asthma.

21 January 2018

1 reference

Tumour necrosis factor (TNFalpha) as a novel therapeutic target in symptomatic corticosteroid dependent asthma

21 January 2018

1 reference

The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial.

21 January 2018

1 reference

New anti-asthma therapies: suppression of the effect of interleukin (IL)-4 and IL-5.

21 January 2018

1 reference

IL-4 and IL-13 dual antagonism: a promising approach to the dilemma of generating effective asthma biotherapeutics.

21 January 2018

1 reference

Anti-interleukin-4 therapy

21 January 2018

1 reference

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

21 January 2018

1 reference

Immunomodulators for allergic respiratory disorders

21 January 2018

1 reference

Changes in sputum composition during 15min of sputum induction in healthy subjects and patients with asthma and chronic obstructive pulmonary disease

21 January 2018

1 reference

Fc RI-mediated thymic stromal lymphopoietin production by interleukin-4-primed human mast cells

21 January 2018

1 reference

IL-33 can promote survival, adhesion and cytokine production in human mast cells

21 January 2018

1 reference

Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation

21 January 2018

1 reference

Th1/Th2 Cytokines Reciprocally RegulateIn VitroPulmonary Angiogenesis via CXC Chemokine Synthesis

21 January 2018

1 reference

Genetics of allergic disease

21 January 2018

1 reference

Natural killer T cells in bronchial biopsies from human allergen challenge model of allergic asthma

21 January 2018

1 reference

Association between leukotriene receptor antagonist therapy and Churg-Strauss syndrome: an analysis of the FDA AERS database

21 January 2018

1 reference

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/ERS.10.57

1 reference

23 August 2017

1 reference

PubMed ID

20923340