New light on the anti-colitic actions of therapeutic aminosalicylates: the role of heme oxygenase (Q37772727)

22 August 2017

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title

New light on the anti-colitic actions of therapeutic aminosalicylates: the role of heme oxygenase (English)

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22 August 2017

Brendan J R Whittle

1

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PubMed ID

20631420

22 August 2017

Csaba Varga

series ordinal

2

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22 August 2017

1 May 2010

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22 August 2017

Pharmacological Reports

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22 August 2017

62

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22 August 2017

3

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22 August 2017

548-556

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Pharmacological and clinical aspects of heme oxygenase

22 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Superoxide, hydroxyl and fatty acid radical scavenging by aminosalicylates. Direct evaluation with electron spin resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Expression of heat shock protein 32 (hemoxygenase-1) in the normal and inflamed human stomach and colon: an immunohistochemical study

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase and carbon monoxide initiate homeostatic signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Nitric oxide synthase activity in ulcerative colitis and Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

The effect of anti-inflammatory drugs on eicosanoid formation in a chronic model of inflammatory bowel disease in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Carbon monoxide liberated from carbon monoxide-releasing molecule CORM-2 attenuates inflammation in the liver of septic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Opposite effect of oxidative stress on inducible nitric oxide synthase and haem oxygenase-1 expression in intestinal inflammation: anti-inflammatory effect of carbon monoxide

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Clinical implications of oxidative stress and antioxidant therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Inhibition of interleukin-1-stimulated NF-kappaB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Effect of heme oxygenase-1 induction by octreotide on TNBS-induced colitis

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https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Inhibition of prostaglandin biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Generation of bile pigments by haem oxygenase: a refined cellular strategy in response to stressful insults.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase/carbon monoxide-biliverdin pathway down regulates neutrophil rolling, adhesion and migration in acute inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Intestinal anti-inflammatory activity of UR-12746, a novel 5-ASA conjugate, on acute and chronic experimental colitis in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

The role of carbon monoxide in the gastrointestinal tract.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Oxidant defense mechanisms in the human colon

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Modulation of human colonic arachidonic acid metabolism by sulfasalazine.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Glutathione content of colonic mucosa: evidence for oxidative damage in active ulcerative colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

The involvement of heme oxygenase-1 activity in the therapeutic actions of 5-aminosalicylic acid in rat colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

MMX mesalamine: a novel high-dose, once-daily 5-aminosalicylate formulation for the treatment of ulcerative colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Gliotoxin reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice: evidence of the connection between heme oxygenase-1 and the nuclear factor-kappaB pathway in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Once-daily, high-concentration MMX mesalamine in active ulcerative colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Carbon monoxide liberated from CO-releasing molecule (CORM-2) attenuates ischemia/reperfusion (I/R)-induced inflammation in the small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Time-dependent actions of nitric oxide synthase inhibition on colonic inflammation induced by trinitrobenzene sulphonic acid in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

2',4',6'-tris(methoxymethoxy) chalcone protects against trinitrobenzene sulfonic acid-induced colitis and blocks tumor necrosis factor-alpha-induced intestinal epithelial inflammation via heme oxygenase 1-dependent and independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase and oxidative stress. Evidence of involvement of bilirubin as physiological protector against oxidative damage

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Inhibition of antibody secretion by 5-aminosalicylic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

The heme oxygenase system: a regulator of second messenger gases

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

The heme oxygenase system: update 2005.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

A carbon monoxide-releasing molecule (CORM-3) abrogates polymorphonuclear granulocyte-induced activation of endothelial cells and mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Carbon monoxide-releasing molecules (CO-RMs): vasodilatory, anti-ischaemic and anti-inflammatory activities.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase-1: a new therapeutic target for inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Biliverdin protects the functional integrity of a transplanted syngeneic small bowel

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase-1: a provenance for cytoprotective pathways in the kidney and other tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase-1: unleashing the protective properties of heme

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Mesalamine delivery systems: do they really make much difference?

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Circulating antioxidants in ulcerative colitis and their relationship to disease severity and activity

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

5-ASA and lycopene decrease the oxidative stress and inflammation induced by iron in rats with colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Cost effectiveness of ulcerative colitis surveillance in the setting of 5-aminosalicylates

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces chronic colonic inflammation in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Systematic review: the pharmacokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Antioxidant effects of aminosalicylates and potential new drugs for inflammatory bowel disease: assessment in cell-free systems and inflamed human colorectal biopsies.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Inflammatory bowel disease--a radical view

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heat shock proteins as emerging therapeutic targets

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Effects of topical treatment of sodium butyrate and 5-aminosalicylic acid on expression of trefoil factor 3, interleukin 1beta, and nuclear factor kappaB in trinitrobenzene sulphonic acid induced colitis in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Bilirubin is an antioxidant of possible physiological importance

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Increased intestinal expression of heme oxygenase-1 and its localization in patients with ulcerative colitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Protective role of heme oxygenase-1 in renal ischemia

1 reference

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7 January 2021

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Carbon Monoxide-Releasing Molecules Modulate Leukocyte-Endothelial Interactions under Flow

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete?

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

1 reference

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7 January 2021

Modulation by heme and zinc protoporphyrin of colonic heme oxygenase-1 and experimental inflammatory bowel disease in the rat

1 reference

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7 January 2021

Nitric oxide-modulating agents for gastrointestinal disorders

1 reference

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7 January 2021

Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970312-1

7 January 2021

Heme oxygenase: a novel target for the modulation of the inflammatory response

1 reference

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7 January 2021

Heme oxygenase isoform expression in cellular and antibody-mediated models of acute inflammation in the rat

1 reference

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7 January 2021

Carbon monoxide: endogenous production, physiological functions, and pharmacological applications

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7 January 2021

10.1016/S1734-1140(10)70312-1

Identifiers

DOI

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22 August 2017

1 reference

PubMed ID

20631420