Intestinal anti-inflammatory activity of UR-12746, a novel 5-ASA conjugate, on acute and chronic experimental colitis in the rat (Q35042603)

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9 November 2019

title

Intestinal anti-inflammatory activity of UR-12746, a novel 5-ASA conjugate, on acute and chronic experimental colitis in the rat (English)

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9 November 2019

1

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9 November 2019

Manuel Merlos

3

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9 November 2019

author name string

M Garrido

2

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9 November 2019

M I Torres

4

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9 November 2019

A Zarzuelo

5

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9 November 2019

language of work or name

English

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publication date

1 August 2000

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British Journal of Pharmacology

9 November 2019

published in

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9 November 2019

volume

130

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9 November 2019

issue

8

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9 November 2019

page(s)

1949-1959

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Alternatives to Sulfasalazine: A Meta-analysis of 5-ASA in the Treatment of Ulcerative Colitis

9 November 2019

cites work

1 reference

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Drug therapy of inflammatory bowel disease

8 July 2018

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Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease

8 July 2018

1 reference

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Platelet activating factor: release from colonic mucosa in patients with ulcerative colitis and its effect on colonic secretion

8 July 2018

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Role of cytokines and platelet-activating factor in inflammatory bowel disease. Implications for therapy

8 July 2018

1 reference

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Intestinal epithelial cells contribute to the enhanced generation of platelet activating factor in ulcerative colitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

The role of platelet-activating factor in the pathogenesis of gastrointestinal disease

8 July 2018

1 reference

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Oxidants and free radicals in inflammatory bowel disease

8 July 2018

1 reference

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Salicylates for ulcerative colitis--their mode of action

8 July 2018

1 reference

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Disruption of colonic electrolyte transport in experimental colitis.

8 July 2018

1 reference

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Sulfasalazine inhibits the synthesis of chemotactic lipids by neutrophils

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

The effects of PAF-acether on the cardiovascular system and their inhibition by a new highly specific PAF-acether receptor antagonist BN 52021.

8 July 2018

1 reference

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Pharmacological actions of WEB 2086, a new specific antagonist of platelet activating factor.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

Role of platelet-activating factor in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine and prednisolone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

Role of interleukin 1 in inflammatory bowel disease--enhanced production during active disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

Role of reactive oxygen metabolites in experimental colitis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

Effect of aminophenols (5-ASA and 4-ASA) on colonic interleukin-1 generation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572265

Direct evidence of oxidative damage in acute and chronic phases of experimental colitis in rats

8 July 2018

1 reference

12 December 2020

Lexipafant (BB-882), a platelet activating factor receptor antagonist, ameliorates mucosal inflammation in an animal model of colitis

1 reference

12 December 2020

Prolonged colonic epithelial hyporesponsiveness after colitis: role of inducible nitric oxide synthase

1 reference

12 December 2020

Sulfasalazine revisited: a meta-analysis of 5-aminosalicylic acid in the treatment of ulcerative colitis

1 reference

12 December 2020

Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models

1 reference

12 December 2020

Possible mode of action of 5-aminosalicylic acid

1 reference

12 December 2020

Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid

1 reference

12 December 2020

Enhanced synthesis of leukotriene B4 by colonic mucosa in inflammatory bowel disease

1 reference

12 December 2020

Platelet activating factor in stool from patients with ulcerative colitis and Crohn's disease

1 reference

12 December 2020

The role of intestinal bacteria in the metabolism of salicylazosulfapyridine

1 reference

12 December 2020

Effect of quercitrin on acute and chronic experimental colitis in the rat

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12 December 2020

Inhibition by ticlopidine of Paf-acether-induced in vitro aggregation of rabbit and human platelets

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12 December 2020

A comparative analysis of two models of colitis in rats

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12 December 2020

Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal

1 reference

12 December 2020

Platelet-activating factor and interleukin 1 are involved in colonic dysmotility in experimental colitis in rats

1 reference

12 December 2020

Leukocyte-induced vascular protein leakage in cat mesentery

1 reference

12 December 2020

Assessment of the role of platelet-activating factor in an animal model of inflammatory bowel disease

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12 December 2020

BPC-15 reduces trinitrobenzene sulfonic acid-induced colonic damage in rats

1 reference

12 December 2020

Azo reduction of salicyl-azo-sulphapyridine in germ-free and conventional rats

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12 December 2020

Determination of glutathione and glutathione disulfide in biological samples

1 reference

12 December 2020

Hapten-induced model of chronic inflammation and ulceration in the rat colon

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0703505

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10952687%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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9 November 2019

PubMed publication ID

10952687

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