Autophagy in Alzheimer's disease (Q37768450)

22 August 2017

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title

Autophagy in Alzheimer's disease (English)

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22 August 2017

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7

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22 August 2017

Renato X Santos

2

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Paula I. Moreira

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Paula I Moreira

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1

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Xiongwei Zhu

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3

object named as

Xiongwei Zhu

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22 August 2017

5

Mark A Smith

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22 August 2017

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Gemma Casadesus

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22 August 2017

4

Hyoung-gon Lee

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22 August 2017

1 July 2010

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

22 August 2017

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22 August 2017

10

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22 August 2017

7

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22 August 2017

1209-1218

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

22 August 2017

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Autophagy fights disease through cellular self-digestion

21 January 2018

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Consequences of the selective blockage of chaperone-mediated autophagy

21 January 2018

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Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy

21 January 2018

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The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes

21 January 2018

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Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

21 January 2018

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Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival

21 January 2018

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Influence of autophagy genes on ion-channel-dependent neuronal degeneration in Caenorhabditis elegans

21 January 2018

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Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

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Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

21 January 2018

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Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

21 January 2018

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Autophagosome formation: core machinery and adaptations

21 January 2018

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The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

21 January 2018

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Regulation of macroautophagy by mTOR and Beclin 1 complexes

21 January 2018

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Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

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Role and regulation of starvation-induced autophagy in the Drosophila fat body

21 January 2018

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Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

21 January 2018

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siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

21 January 2018

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Autophagy: principles and significance in health and disease

21 January 2018

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Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG

21 January 2018

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Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

21 January 2018

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Autophagy: basic principles and relevance to disease

21 January 2018

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Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy

21 January 2018

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Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

21 January 2018

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A protein conjugation system essential for autophagy

21 January 2018

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Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

21 January 2018

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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

21 January 2018

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The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy

21 January 2018

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Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

21 January 2018

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Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

21 January 2018

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Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy

21 January 2018

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The itinerary of a vesicle component, Aut7p/Cvt5p, terminates in the yeast vacuole via the autophagy/Cvt pathways

21 January 2018

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Formation process of autophagosome is traced with Apg8/Aut7p in yeast

21 January 2018

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

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Discovery of Atg5/Atg7-independent alternative macroautophagy

21 January 2018

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Role for Rab7 in maturation of late autophagic vacuoles

21 January 2018

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Maturation of autophagic vacuoles in Mammalian cells

21 January 2018

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Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activation

21 January 2018

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Neuronal macroautophagy: from development to degeneration

21 January 2018

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Hypothalamic mTOR signaling regulates food intake

21 January 2018

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Autophagosomes in GFP-LC3 Transgenic Mice.

21 January 2018

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

21 January 2018

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Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

21 January 2018

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Mitochondria: a therapeutic target in neurodegeneration

21 January 2018

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Autophagy impairment stimulates PS1 expression and gamma-secretase activity

21 January 2018

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Autophagy protects neuron from Abeta-induced cytotoxicity

21 January 2018

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Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila

21 January 2018

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Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

21 January 2018

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Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease

21 January 2018

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Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease

21 January 2018

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Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.

21 January 2018

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Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

21 January 2018

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Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis

21 January 2018

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Fine structural localization of acid phosphatase in senile plaques in Alzheimer's presenile dementia.

21 January 2018

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Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease

21 January 2018

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Autophagocytosis of mitochondria is prominent in Alzheimer disease.

21 January 2018

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Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

21 January 2018

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A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis

21 January 2018

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Cellular injury induced by oxidative stress is mediated through lysosomal damage.

21 January 2018

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Alzheimer disease-associated peptide, amyloid beta40, inhibits vascular regeneration with induction of endothelial autophagy.

21 January 2018

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Autophagy, amyloidogenesis and Alzheimer disease

21 January 2018

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

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The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons.

21 January 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

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Autophagy and its possible roles in nervous system diseases, damage and repair

21 January 2018

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Rapamycin alleviates toxicity of different aggregate-prone proteins

21 January 2018

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Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

21 January 2018

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Growing roles for the mTOR pathway

21 January 2018

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Role of mTOR in physiology and pathology of the nervous system

21 January 2018

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Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

21 January 2018

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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 January 2018

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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

21 January 2018

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Lithium induces autophagy by inhibiting inositol monophosphatase

21 January 2018

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A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.

21 January 2018

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Lithium delays progression of amyotrophic lateral sclerosis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERN.10.84

1 reference

release_hh7xyzrthja6xeqhpba3adgfsm

22 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hh7xyzrthja6xeqhpba3adgfsm

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

20586699

1 reference

PubMed ID

20586699