Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities. (Q37737945)

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Aberrant DNA methylation in melanoma: biomarker and therapeutic opportunities (English)

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Nicholas Theodosakis

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Marcus Bosenberg

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Enhancer methylation dynamics contribute to cancer plasticity and patient mortality

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Common BRAF(V600E)-directed pathway mediates widespread epigenetic silencing in colorectal cancer and melanoma

23 August 2017

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Comparison of Methyl-capture Sequencing vs. Infinium 450K methylation array for methylome analysis in clinical samples

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DNA Methylation Analysis: Choosing the Right Method

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DNA methylation subgroups in melanoma are associated with proliferative and immunological processes

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A gene expression signature identifying transient DNMT1 depletion as a causal factor of cancer-germline gene activation in melanoma

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Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

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Genomic Classification of Cutaneous Melanoma

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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

23 August 2017

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Epigenetic reprogramming of melanoma cells by vitamin C treatment

23 August 2017

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Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

23 August 2017

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Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells

23 August 2017

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Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo

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DNA methylation biomarkers: cancer and beyond

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Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome

23 August 2017

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5-Hydroxymethylcytosine expression in metastatic melanoma versus nodal nevus in sentinel lymph node biopsies

23 August 2017

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DNA methylation profiles in primary cutaneous melanomas are associated with clinically significant pathologic features.

23 August 2017

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Identification of a melanoma susceptibility locus and somatic mutation in TET2.

23 August 2017

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CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity

23 August 2017

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DNA methylation characteristics of primary melanomas with distinct biological behaviour.

23 August 2017

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Prognostic value of CpG island methylator phenotype among colorectal cancer patients: a systematic review and meta-analysis.

23 August 2017

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Clinical development of demethylating agents in hematology

23 August 2017

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Ras and Rac1, frequently mutated in melanomas, are activated by superoxide anion, modulate Dnmt1 level and are causally related to melanocyte malignant transformation

23 August 2017

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Transposable hypomethylation is associated with metastatic capacity of primary melanomas

23 August 2017

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Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents.

23 August 2017

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Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine

23 August 2017

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Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network

23 August 2017

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Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.

23 August 2017

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Mahanine restores RASSF1A expression by down-regulating DNMT1 and DNMT3B in prostate cancer cells

23 August 2017

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Prognostic implication of the CpG island methylator phenotype in colorectal cancers depends on tumour location

23 August 2017

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The role of miR-18b in MDM2-p53 pathway signaling and melanoma progression

23 August 2017

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G-cimp status prediction of glioblastoma samples using mRNA expression data

23 August 2017

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Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

23 August 2017

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Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients

23 August 2017

1 reference

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

23 August 2017

1 reference

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Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.

23 August 2017

1 reference

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5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis

23 August 2017

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The BRAF(V600E) causes widespread alterations in gene methylation in the genome of melanoma cells

23 August 2017

1 reference

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Cross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma.

23 August 2017

1 reference

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Epigenetic regulation of microRNA genes and the role of miR-34b in cell invasion and motility in human melanoma

23 August 2017

1 reference

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DNA demethylation dynamics

23 August 2017

1 reference

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Improved survival with vemurafenib in melanoma with BRAF V600E mutation

23 August 2017

1 reference

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Methylation levels of the "long interspersed nucleotide element-1" repetitive sequences predict survival of melanoma patients

23 August 2017

1 reference

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Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

23 August 2017

1 reference

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Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling

23 August 2017

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DNA-methylation profiling distinguishes malignant melanomas from benign nevi

23 August 2017

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Mutant IDH1 confers an in vivo growth in a melanoma cell line with BRAF mutation

23 August 2017

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Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma

23 August 2017

1 reference

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Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci

23 August 2017

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

23 August 2017

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Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies

23 August 2017

1 reference

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Aberrant DNA methylation in malignant melanoma

23 August 2017

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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

23 August 2017

1 reference

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Final version of 2009 AJCC melanoma staging and classification

23 August 2017

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Targeting DNA methylation

23 August 2017

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Genome-wide screen of promoter methylation identifies novel markers in melanoma.

23 August 2017

1 reference

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

23 August 2017

1 reference

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CpG island methylator phenotype predicts progression of malignant melanoma

23 August 2017

1 reference

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A microRNA DNA methylation signature for human cancer metastasis

23 August 2017

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Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

23 August 2017

1 reference

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Frequent p16-independent inactivation of p14ARF in human melanoma

23 August 2017

1 reference

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Sensitive Melting Analysis after Real Time- Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection

23 August 2017

1 reference

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Epigenetic silencing of novel tumor suppressors in malignant melanoma

23 August 2017

1 reference

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Estrogen receptor-alpha methylation predicts melanoma progression

23 August 2017

1 reference

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Predictive utility of circulating methylated DNA in serum of melanoma patients receiving biochemotherapy.

23 August 2017

1 reference

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Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

23 August 2017

1 reference

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DNA methylation and human disease

23 August 2017

1 reference

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MGMT gene silencing and benefit from temozolomide in glioblastoma

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

XAF1 expression is significantly reduced in human melanoma

23 August 2017

1 reference

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The history of cancer epigenetics

23 August 2017

1 reference

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The power and the promise of DNA methylation markers

23 August 2017

1 reference

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The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

An essential role for DNA methyltransferase DNMT3B in cancer cell survival

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic PTEN silencing in malignant melanomas without PTEN mutation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

CpG island methylator phenotype in colorectal cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

23 August 2017

1 reference

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The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Tissue inhibitor of metalloproteinase-3 (TIMP3) expression decreases during melanoma progression and inhibits melanoma cell migration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Promoter Methylation of PTEN Is a Significant Prognostic Factor in Melanoma Survival.

23 August 2017

1 reference

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Epigenetics of human melanoma: promises and challenges.

23 August 2017

1 reference

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Methodological aspects of whole-genome bisulfite sequencing analysis.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Key clinical observations after 5-azacytidine and decitabine treatment of myelodysplastic syndromes suggest practical solutions for better outcomes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Loss of microRNA-205 expression is associated with melanoma progression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic inactivation of RASSF1a in uveal melanoma.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

A comparison of existing global DNA methylation assays to low-coverage whole-genome bisulfite sequencing for epidemiological studies.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

MicroRNA epigenetic signatures in human disease.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Allosteric control of mammalian DNA methyltransferases - a new regulatory paradigm

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

MiR-211 is epigenetically regulated by DNMT1 mediated methylation and inhibits EMT of melanoma cells by targeting RAB22A.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

miR-196b regulates gastric cancer cell proliferation and invasion via PI3K/AKT/mTOR signaling pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

DNMT3b Modulates Melanoma Growth by Controlling Levels of mTORC2 Component RICTOR.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Immunotherapy for advanced melanoma: future directions.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

MicroRNA 211 Functions as a Metabolic Switch in Human Melanoma Cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

DNA methylation contributes toward silencing of antioncogenic microRNA-203 in human and canine melanoma cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic regulation of p14ARF and p16INK4A expression in cutaneous and uveal melanoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

MiR-203 inhibits melanoma invasive and proliferative abilities by targeting the polycomb group gene BMI1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Acute depletion redefines the division of labor among DNA methyltransferases in methylating the human genome.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

KIT is a frequent target for epigenetic silencing in cutaneous melanoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Methylated tissue factor pathway inhibitor 2 (TFPI2) DNA in serum is a biomarker of metastatic melanoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

MicroRNA-34b/c suppresses uveal melanoma cell proliferation and migration through multiple targets.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic regulation of microRNA-375 and its role in melanoma development in humans.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Transcriptional and post-transcriptional control of DNA methyltransferase 3B is regulated by phosphatidylinositol 3 kinase/Akt pathway in human hepatocellular carcinoma cell lines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

TSLC1 gene silencing in cutaneous melanoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

CpG island methylation profiling in human melanoma cell lines.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Drug sensitivity prediction by CpG island methylation profile in the NCI-60 cancer cell line panel.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Wnt inhibitory factor-1 gene transfer inhibits melanoma cell growth

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Methylation status of the SOCS3 gene in human malignant melanomas.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Promoter methylation profiling of 30 genes in human malignant melanoma.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

DNA methylation: a timeline of methods and applications

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Low frequency of p16/CDKN2A methylation in sporadic melanoma: comparative approaches for methylation analysis of primary tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic inactivation of tumor suppressor genes in serum of patients with cutaneous melanoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Significant impact of promoter hypermethylation and the 540 C>T polymorphism of CDKN2A in cutaneous melanoma of the vertical growth phase

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Attenuation of genome-wide 5-methylcytosine level is an epigenetic feature of cutaneous malignant melanomas

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Integrative discovery of CD98 as a melanoma biomarker.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

DNA Methylation Inhibitors in Cancer Therapy: The Immunity Dimension.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Diagnostic utility of 5-hydroxymethylcytosine immunohistochemistry in melanocytic proliferations

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Promoter CpG island hypermethylation in dysplastic nevus and melanoma: CLDN11 as an epigenetic biomarker for malignancy.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

TFPI2 methylation can serve as an epigenetic biomarker of metastatic melanoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

High frequency of p16(INK4A) promoter methylation in NRAS-mutated cutaneous melanoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

An essential role for DNA methyltransferase 3a in melanoma tumorigenesis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Identification of novel epigenetically modified genes in human melanoma via promoter methylation gene profiling.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Overload of the heat-shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-beta-activated kinase 1.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Altered expressions of HOX genes in human cutaneous malignant melanoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Methylation-regulated expression of HLA class I antigens in melanoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Lack of genetic and epigenetic changes in CDKN2A in melanocytic nevi.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

Role of the INK4a locus in tumor suppression and cell mortality.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5381063

MGMT promoter methylation is associated with temozolomide response and prolonged progression-free survival in disseminated cutaneous melanoma

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS13148-017-0332-8

21 January 2018

Methylation-specific PCR

1 reference

12 December 2020

Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic melanoma biopsies

1 reference

12 December 2020

p16INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma

1 reference

12 December 2020

Cloning of a mammalian DNA methyltransferase

1 reference

12 December 2020

CpG island methylator phenotype in cancer

1 reference

12 December 2020

Prognostic significance of MGMT gene promoter methylation in differently treated metastatic melanomas

1 reference

12 December 2020

Loss of PTEN promotes tumor development in malignant melanoma

1 reference

12 December 2020

Epigenetic silencing of the PTEN gene in melanoma

1 reference

12 December 2020

Are circulating tumor cells an independent prognostic factor in patients with high-risk melanoma?

1 reference

12 December 2020

5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi

1 reference

12 December 2020

Methylation of PTEN as a prognostic factor in malignant melanoma of the skin

1 reference

12 December 2020

Prognostic significance of CpG island methylator phenotype and microsatellite instability in gastric carcinoma

1 reference

12 December 2020

10.1186/S13148-017-0332-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396701%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

17 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28396701%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

28396701

1 reference