Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome (Q35023463)

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English	Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome	scientific article

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scholarly article

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Europe PubMed Central

5 August 2017

Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome (English)

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5 August 2017

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brain metastasis

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based on heuristic

inferred from title

Diego M Marzese

1

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7

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15

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12

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Donald L Morton

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author name string

Michelle Liu

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Jamie L Huynh

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Hajime Hirose

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Nicholas C Donovan

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Kelly T Huynh

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Kelly Chong

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David Cheng

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Ryo Tanaka

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Jinhua Wang

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Garni Barkhoudarian

13

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Daniel F Kelly

14

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publication date

30 September 2014

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5 August 2017

Pigment Cell & Melanoma Research

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28

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1

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82-93

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describes a project that uses

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based on heuristic

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Multi-platform Genome-wide Analysis of Melanoma Progression to Brain Metastasis.

1 reference

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8 July 2018

DNA methylation and gene deletion analysis of brain metastases in melanoma patients identifies mutually exclusive molecular alterations

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Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis.

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Demonstration of a melanoma-specific CD44 alternative splicing pattern that remains qualitatively stable, but shows quantitative changes during tumour progression

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Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial-mesenchymal transition

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Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell.

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8 July 2018

CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

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Hyaluronan-CD44 interactions as potential targets for cancer therapy.

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Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma

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The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events

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Estrogen receptor-alpha methylation predicts melanoma progression

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Regulation of CD44 alternative splicing by SRm160 and its potential role in tumor cell invasion

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Structure of PTB bound to RNA: specific binding and implications for splicing regulation

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CD44 is required for two consecutive steps in HGF/c-Met signaling.

1 reference

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8 July 2018

The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4.

1 reference

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Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid

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1 reference

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8 July 2018

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8 July 2018

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1 reference

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8 July 2018

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1 reference

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Melanoma-related mortality and productivity losses in the USA, 1990-2008.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/25169209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/25169209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/PCMR.12307

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31 May 2020

1 reference

Europe PubMed Central

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31 May 2020

1 reference

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31 May 2020

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