Inducible gene expression: diverse regulatory mechanisms (Q37737546)

22 August 2017

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title

Inducible gene expression: diverse regulatory mechanisms (English)

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22 August 2017

1

Vikki M Weake

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22 August 2017

2

Jerry L Workman

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22 August 2017

27 April 2010

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22 August 2017

Nature Reviews Genetics

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22 August 2017

11

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22 August 2017

426-437

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22 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/nrg2781

22 August 2017

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cites work

RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

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RNA polymerase is poised for activation across the genome

31 March 2020

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A high-resolution map of active promoters in the human genome

31 March 2020

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A chromatin landmark and transcription initiation at most promoters in human cells

31 March 2020

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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Control of developmental regulators by Polycomb in human embryonic stem cells

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Multilayered control of gene expression by stress-activated protein kinases.

31 March 2020

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Defining mechanisms that regulate RNA polymerase II transcription in vivo

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Transcriptional regulation and the role of diverse coactivators in animal cells

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Transcriptional activation by recruitment

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A unified theory of gene expression

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Yeast Gal4: a transcriptional paradigm revisited

31 March 2020

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A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor

31 March 2020

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Gal80 confers specificity on HAT complex interactions with activators

31 March 2020

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Novel Gal3 proteins showing altered Gal80p binding cause constitutive transcription of Gal4p-activated genes in Saccharomyces cerevisiae

31 March 2020

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Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of Saccharomyces cerevisiae

31 March 2020

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The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex

31 March 2020

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Analysis of the galactose signal transduction pathway in Saccharomyces cerevisiae: interaction between Gal3p and Gal80p

31 March 2020

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Activation of Gal4p by galactose-dependent interaction of galactokinase and Gal80p

31 March 2020

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Gene activation by dissociation of an inhibitor from a transcriptional activation domain

31 March 2020

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SAGA is an essential in vivo target of the yeast acidic activator Gal4p

31 March 2020

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Independent recruitment in vivo by Gal4 of two complexes required for transcription

31 March 2020

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The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.

31 March 2020

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Association of the Mediator complex with enhancers of active genes

31 March 2020

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Transcriptional activating regions target a cyclin-dependent kinase.

31 March 2020

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An activator target in the RNA polymerase II holoenzyme

31 March 2020

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Targeting of Swi/Snf to the yeast GAL1 UAS G requires the Mediator, TAF IIs, and RNA polymerase II.

31 March 2020

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Differential requirement of SAGA components for recruitment of TATA-box-binding protein to promoters in vivo

31 March 2020

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The Saccharomyces cerevisiae Srb8-Srb11 complex functions with the SAGA complex during Gal4-activated transcription

31 March 2020

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GAL4 activates transcription in Drosophila.

31 March 2020

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GAL4 activates gene expression in mammalian cells

31 March 2020

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Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors

31 March 2020

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Positive activation of gene expression

31 March 2020

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Histones: annotating chromatin

31 March 2020

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Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

31 March 2020

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Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II

31 March 2020

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Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

31 March 2020

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The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro

31 March 2020

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The logic of chromatin architecture and remodelling at promoters

31 March 2020

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Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex

31 March 2020

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Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays

31 March 2020

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Activation domain-specific and general transcription stimulation by native histone acetyltransferase complexes

31 March 2020

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Mediator complexes and eukaryotic transcription regulation: an overview

31 March 2020

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Systematic in vivo structure-function analysis of p300 in hematopoiesis

31 March 2020

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PCAF interacts with tax and stimulates tax transactivation in a histone acetyltransferase-independent manner

31 March 2020

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An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p

31 March 2020

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The biology of chromatin remodeling complexes

31 March 2020

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Activator control of nucleosome occupancy in activation and repression of transcription

31 March 2020

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Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators

31 March 2020

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Coordination of PIC Assembly and Chromatin Remodeling During Differentiation-Induced Gene Activation

31 March 2020

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Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes.

31 March 2020

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Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes.

31 March 2020

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SWI/SNF displaces SAGA-acetylated nucleosomes

31 March 2020

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RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation

31 March 2020

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Histones are first hyperacetylated and then lose contact with the activated PHO5 promoter.

31 March 2020

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Regulation of chromatin remodeling by inositol polyphosphates

31 March 2020

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SWI/SNF-dependent chromatin remodeling of RNR3 requires TAF(II)s and the general transcription machinery

31 March 2020

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Mediator requirement downstream of chromatin remodeling during transcriptional activation of CHA1 in yeast

31 March 2020

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Exposing the core promoter is sufficient to activate transcription and alter coactivator requirement at RNR3.

31 March 2020

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Transcriptional activators are dispensable for transcription in the absence of Spt6-mediated chromatin reassembly of promoter regions

31 March 2020

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Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II.

31 March 2020

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Evidence for nucleosome depletion at active regulatory regions genome-wide

31 March 2020

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Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci

31 March 2020

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The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity

31 March 2020

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The 5' ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I.

31 March 2020

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Imaging Drosophila gene activation and polymerase pausing in vivo

31 March 2020

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Sodium salicylate decreases intracellular ATP, induces both heat shock factor binding and chromosomal puffing, but does not induce hsp 70 gene transcription in Drosophila.

31 March 2020

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Nucleosome loss activates yeast downstream promoters in vivo

31 March 2020

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Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo

31 March 2020

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Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B.

31 March 2020

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RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells

31 March 2020

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A conserved RING finger protein required for histone H2B monoubiquitination and cell size control.

31 March 2020

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The Paf1 complex is essential for histone monoubiquitination by the Rad6-Bre1 complex, which signals for histone methylation by COMPASS and Dot1p

31 March 2020

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Rad6-dependent ubiquitination of histone H2B in yeast

31 March 2020

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Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter

31 March 2020

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The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B.

31 March 2020

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Histone H2B ubiquitylation is associated with elongating RNA polymerase II

31 March 2020

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Histone ubiquitination: triggering gene activity

31 March 2020

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Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8.

31 March 2020

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Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription.

31 March 2020

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H2B Ubiquitylation Acts as a Barrier to Ctk1 Nucleosomal Recruitment Prior to Removal by Ubp8 within a SAGA-Related Complex

31 March 2020

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Breaking barriers to transcription elongation

31 March 2020

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The RNA polymerase II molecule at the 5' end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged.

31 March 2020

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A highly purified RNA polymerase II elongation control system

31 March 2020

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Synchronous and stochastic patterns of gene activation in the Drosophila embryo

31 March 2020

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NELF and GAGA factor are linked to promoter-proximal pausing at many genes in Drosophila

31 March 2020

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Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila

31 March 2020

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Targeting the MEF2-like transcription factor Smp1 by the stress-activated Hog1 mitogen-activated protein kinase

31 March 2020

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Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress

31 March 2020

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Osmostress-induced transcription by Hot1 depends on a Hog1-mediated recruitment of the RNA Pol II.

31 March 2020

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Stress-induced map kinase Hog1 is part of transcription activation complexes.

31 March 2020

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Induction of Progesterone Target Genes Requires Activation of Erk and Msk Kinases and Phosphorylation of Histone H3

31 March 2020

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Mitogen-induced recruitment of ERK and MSK to SRE promoter complexes by ternary complex factor Elk-1.

31 March 2020

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Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling

31 March 2020

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The Stress-Activated Hog1 Kinase Is a Selective Transcriptional Elongation Factor for Genes Responding to Osmotic Stress

31 March 2020

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Genome-wide location analysis of the stress-activated MAP kinase Hog1 in yeast.

31 March 2020

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Activated signal transduction kinases frequently occupy target genes

31 March 2020

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Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes.

31 March 2020

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Shifting players and paradigms in cell-specific transcription

31 March 2020

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Cracking the RNA polymerase II CTD code

31 March 2020

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Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis

31 March 2020

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Stress-induced oligomerization and chromosomal relocalization of heat-shock factor

31 March 2020

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ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor.

31 March 2020

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Identification in vivo of different rate-limiting steps associated with transcriptional activators in the presence and absence of a GAGA element

31 March 2020

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DNA sequence requirements for generating paused polymerase at the start of hsp70

31 March 2020

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Molecular characterization of Drosophila NELF

31 March 2020

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NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

31 March 2020

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Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock

31 March 2020

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The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions

31 March 2020

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Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression

31 March 2020

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Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS.

31 March 2020

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Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci

31 March 2020

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12 December 2020

Direct cloning of DNA that interacts in vivo with a specific protein: application to RNA polymerase II and sites of pausing in Drosophila

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12 December 2020

Multiple chromatin-bound protein kinases assemble factors that regulate insulin gene transcription

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12 December 2020

P-TEFb kinase recruitment and function at heat shock loci

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12 December 2020

Quantitation of putative activator-target affinities predicts transcriptional activating potentials

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12 December 2020

Identifiers

DOI

10.1038/NRG2781

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22 August 2017

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PubMed ID

20421872