Poly(ADP-ribose) metabolism in brain and its role in ischemia pathology (Q37735746)

22 August 2017

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title

Poly(ADP-ribose) metabolism in brain and its role in ischemia pathology (English)

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22 August 2017

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Joanna B Strosznajder

series ordinal

4

object named as

Joanna Benigna Strosznajder

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22 August 2017

3

Henryk Jesko

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PubMed ID

20411356

22 August 2017

Robert P Strosznajder

series ordinal

1

object named as

Robert Piotr Strosznajder

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22 August 2017

Kinga Czubowicz

2

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22 August 2017

23 April 2010

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22 August 2017

Molecular Neurobiology

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22 August 2017

41

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22 August 2017

2-3

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22 August 2017

187-196

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https://scigraph.springernature.com/pub.10.1007/s12035-010-8124-6

22 August 2017

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cites work

Poly(ADP-ribose) polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12035-010-8124-6

Role of Parp-1 in suppressing spontaneous deletion mutation in the liver and brain of mice at adolescence and advanced age.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12035-010-8124-6

Poly(ADP-ribose) polymerase as a drug target for cardiovascular disease and cancer: an update

21 January 2018

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12 December 2020

Delayed combinatorial treatment with flavopiridol and minocycline provides longer term protection for neuronal soma but not dendrites following global ischemia.

1 reference

12 December 2020

Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

1 reference

12 December 2020

Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.

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12 December 2020

Poly(ADP-ribose) (PAR) polymer is a death signal

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12 December 2020

Use of a poly(ADP-ribose) polymerase inhibitor to suppress inflammation and neuronal death after cerebral ischemia-reperfusion

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12 December 2020

Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats.

1 reference

12 December 2020

Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia

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12 December 2020

Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair

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12 December 2020

Nicotinamide abrogates acute lung injury caused by ischaemia/reperfusion

1 reference

12 December 2020

Sex differences in caspase activation after stroke

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12 December 2020

PARP-1 activation in the ERK signaling pathway

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12 December 2020

Pathways to ischemic neuronal cell death: are sex differences relevant?

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12 December 2020

Antioxidant therapy in acute central nervous system injury: current state

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12 December 2020

Inhibition of poly(ADP-ribose) polymerase: reduction of ischemic injury and attenuation of N-methyl-D-aspartate-induced neurotransmitter dysregulation

1 reference

12 December 2020

Parthanatos, a messenger of death

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12 December 2020

Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.

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12 December 2020

Effect of amyloid beta peptide on poly(ADP-ribose) polymerase activity in adult and aged rat hippocampus.

1 reference

12 December 2020

A specific isoform of poly(ADP-ribose) glycohydrolase is targeted to the mitochondrial matrix by a N-terminal mitochondrial targeting sequence.

1 reference

12 December 2020

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

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12 December 2020

NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes

1 reference

12 December 2020

Poly(ADP-ribose) polymerase-1 modulation of in vivo response of brain hypoxia-inducible factor-1 to hypoxia/reoxygenation is mediated by nitric oxide and factor inhibiting HIF.

1 reference

12 December 2020

The structure of human ADP-ribosylhydrolase 3 (ARH3) provides insights into the reversibility of protein ADP-ribosylation

1 reference

12 December 2020

Anti-inflammatory effects of PJ34, a poly(ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice

1 reference

12 December 2020

Poly(ADP-ribose) polymerase during reperfusion after transient forebrain ischemia: its role in brain edema and cell death

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12 December 2020

Effect of aging and oxidative/genotoxic stress on poly(ADP-ribose) polymerase-1 activity in rat brain

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12 December 2020

Mitochondrial and nuclear cross talk in cell death: parthanatos

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12 December 2020

Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

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12 December 2020

Poly(ADP-ribose) polymerase-1 inhibition protects the brain against systemic inflammation.

1 reference

12 December 2020

Human poly(ADP-ribose) glycohydrolase (PARG) gene and the common promoter sequence it shares with inner mitochondrial membrane translocase 23 (TIM23)

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12 December 2020

Neuronal death in brain infarcts in man

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12 December 2020

3-Aminobenzamide reduces brain infarction and neutrophil infiltration after transient focal cerebral ischemia in mice

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12 December 2020

Novel modulators of poly(ADP-ribose) polymerase

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12 December 2020

The effect of reperfusion on neuroprotection using an inhibitor of poly(ADP-ribose) polymerase

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12 December 2020

The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders

1 reference

12 December 2020

Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury

1 reference

12 December 2020

Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage

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12 December 2020

Effect of carvedilol on neuronal survival and poly(ADP-ribose) polymerase activity in hippocampus after transient forebrain ischemia.

1 reference

12 December 2020

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

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12 December 2020

Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia

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12 December 2020

Combinatorial-approached neuroprotection using pan-caspase inhibitor and poly (ADP-ribose) polymerase (PARP) inhibitor following experimental stroke in rats; is there additional benefit?

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12 December 2020

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

1 reference

12 December 2020

Sex differences in minocycline-induced neuroprotection after experimental stroke

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12 December 2020

Poly(ADP-ribose) makes a date with death

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12 December 2020

Hypoxic preconditioning protects human brain endothelium from ischemic apoptosis by Akt-dependent survivin activation

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12 December 2020

Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke

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12 December 2020

Contribution of poly(ADP-ribose) polymerase to postischemic blood-brain barrier damage in rats.

1 reference

12 December 2020

Could serum antibody to poly(ADP-ribose) and/or histone H1 be marker for senile dementia of Alzheimer type?

1 reference

12 December 2020

Poly(ADP-ribose) polymerase inhibition by cilostazol is implicated in the neuroprotective effect against focal cerebral ischemic infarct in rat.

1 reference

12 December 2020

Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation

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12 December 2020

Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection

1 reference

12 December 2020

Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors

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12 December 2020

Cerebral endothelial cell apoptosis after ischemia-reperfusion: role of PARP activation and AIF translocation.

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12 December 2020

Oxidative stress in brain ischemia.

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12 December 2020

Players in the PARP-1 cell-death pathway: JNK1 joins the cast.

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12 December 2020

Poly(ADP-ribose) polymerase 1 accelerates single-strand break repair in concert with poly(ADP-ribose) glycohydrolase

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12 December 2020

PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury.

1 reference

12 December 2020

NAD+ as a metabolic link between DNA damage and cell death.

1 reference

12 December 2020

Absence of poly(ADP-ribose)polymerase-1 alters nuclear factor-kappa B activation and gene expression of apoptosis regulators after reperfusion injury

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12 December 2020

Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity.

1 reference

12 December 2020

Regional differences in the neuroprotective effect of minocycline in a mouse model of global forebrain ischemia

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12 December 2020

Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

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12 December 2020

Nitric oxide, cell bioenergetics and neurodegeneration.

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12 December 2020

Inhibition of poly(ADP-ribose) polymerase attenuates inflammation in a model of chronic colitis

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12 December 2020

Intranasal administration of a PARG inhibitor profoundly decreases ischemic brain injury

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12 December 2020

Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation

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12 December 2020

Critical role of the automodification of poly(ADP-ribose) polymerase-1 in nuclear factor-kappaB-dependent gene expression in primary cultured mouse glial cells.

1 reference

12 December 2020

Inhibition of poly(ADP-ribose) polymerase activity protects hippocampal cells against morphological and ultrastructural alteration evoked by ischemia-reperfusion injury.

1 reference

12 December 2020

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

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12 December 2020

Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase

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12 December 2020

Poly(ADP-ribose) accumulation and enhancement of postischemic brain damage in 110-kDa poly(ADP-ribose) glycohydrolase null mice

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12 December 2020

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

1 reference

12 December 2020

The role of poly(ADP-ribose) polymerase-1 in CNS disease

1 reference

12 December 2020

Poly(ADP-ribose) polymerase: the nuclear target in signal transduction and its role in brain ischemia-reperfusion injury.

1 reference

12 December 2020

The poly(ADP-ribose) glycohydrolase inhibitor gallotannin blocks oxidative astrocyte death.

1 reference

12 December 2020

ADP-ribosyl protein lyase. Purification, properties, and identification of the product

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12 December 2020

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12 December 2020

Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes

1 reference

12 December 2020

Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos).

1 reference

12 December 2020

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

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12 December 2020

Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment

1 reference

12 December 2020

Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain.

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12 December 2020

Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition

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12 December 2020

PARP1 is required for adhesion molecule expression in atherogenesis

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12 December 2020

The harlequin mouse mutation downregulates apoptosis-inducing factor

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12 December 2020

Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain

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12 December 2020

Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat.

1 reference

12 December 2020

Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms

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12 December 2020

Effect of 3-aminobenzamide on Bcl-2, Bax and AIF localization in hippocampal neurons altered by ischemia-reperfusion injury. the immunocytochemical study.

1 reference

12 December 2020

10.1007/S12035-010-8124-6

Identifiers

DOI

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22 August 2017

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PubMed ID

20411356