Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase (Q37714667)

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scientific article published on 23 March 2014

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English	Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase	scientific article published on 23 March 2014

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scholarly article

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22 August 2017

Microglia and motor neurons during disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase (English)

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22 August 2017

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amyotrophic lateral sclerosis

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Katherine E Lewis

1

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11 June 2020

William Bennett

3

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11 June 2020

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Adrian K West

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11 June 2020

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Anna L Rasmussen

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11 June 2020

Meng Inn Chuah

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23 March 2014

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Journal of Neuroinflammation

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describes a project that uses

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https://scigraph.springernature.com/pub.10.1186/1742-2094-11-55

0 references

Regulation of nitric oxide generation by up-regulated arginase I in rat spinal cord injury

1 reference

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23 August 2017

Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS.

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23 August 2017

Ablation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis

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23 August 2017

Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis.

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23 August 2017

Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice

1 reference

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23 August 2017

Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Microglia in ALS: the good, the bad, and the resting

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23 August 2017

Extracellular activation of arginase-1 decreases enterocyte inducible nitric oxide synthase activity during systemic inflammation

1 reference

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23 August 2017

Heterogeneity of microglial activation in the innate immune response in the brain

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23 August 2017

Recent advances in motor neuron disease.

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23 August 2017

Motor neuronal protection by L-arginine prolongs survival of mutant SOD1 (G93A) ALS mice

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23 August 2017

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

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23 August 2017

T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Arginase 1 regulation of nitric oxide production is key to survival of trophic factor-deprived motor neurons

1 reference

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23 August 2017

Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes

1 reference

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23 August 2017

Oxidative Stress: a common denominator in the pathogenesis of amyotrophic lateral sclerosis.

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23 August 2017

The basic aspects of therapeutics in amyotrophic lateral sclerosis

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23 August 2017

Nitric oxide and the immune response

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

L-Arginine availability modulates local nitric oxide production and parasite killing in experimental trypanosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

23 August 2017

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

6 September 2017

Arginase modulates nitric oxide production in activated macrophages.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

28 September 2017

A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

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28 September 2017

Cytokines and olfactory bulb microglia in response to bacterial challenge in the compromised primary olfactory pathway

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23 June 2018

Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis

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23 June 2018

Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

1 September 2018

Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

1 September 2018

Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

1 September 2018

Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3994340

1 September 2018

Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism

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1 September 2018

Cell death in amyotrophic lateral sclerosis: interplay between neuronal and glial cells.

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1 September 2018

Neuroprotective effects of spermine following hypoxic-ischemic-induced brain damage: a mechanistic study

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1 September 2018

Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.

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1 September 2018

Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype.

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1 September 2018

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

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1 September 2018

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1186%2F1742-2094-11-55

21 January 2018

Absence of p53: no effect in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune reactivity in a mouse model of familial ALS correlates with disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Appearance of phagocytic microglia adjacent to motoneurons in spinal cord tissue from a presymptomatic transgenic rat model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage nitric oxide synthase subunits. Purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presymptomatic motor neuron loss and reactive astrocytosis in the SOD1 mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24655927

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-11-55

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11 June 2020

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11 June 2020

1 reference

Europe PubMed Central

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11 June 2020

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