Platelet-derived chemokines: pathophysiology and therapeutic aspects (Q37705023)

22 August 2017

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title

Platelet-derived chemokines: pathophysiology and therapeutic aspects (English)

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22 August 2017

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Hans-Dieter Flad

1

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PubMed ID

20213276

22 August 2017

Ernst Brandt

series ordinal

2

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22 August 2017

7 March 2010

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Cellular and Molecular Life Sciences

22 August 2017

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22 August 2017

67

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22 August 2017

2363-2386

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22 August 2017

14

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https://scigraph.springernature.com/pub.10.1007/s00018-010-0306-x

22 August 2017

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cites work

Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transients

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Formation of neutrophil-activating peptide 2 from platelet-derived connective-tissue-activating peptide III by different tissue proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Identification and characterization of PF4varl, a human gene variant of platelet factor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

CCR5 antagonists: host-targeted antivirals for the treatment of HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Novel interfering bifunctional molecules against the CCR5 coreceptor are efficient inhibitors of HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Secondary lymphoid tissue chemokine mediates T cell-dependent antitumor responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Enhanced expression of Duffy antigen in the lungs during suppurative pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Hemopoietic Cell Expression of the Chemokine Decoy Receptor D6 Is Dynamic and Regulated by GATA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0306-X

Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice

21 January 2018

1 reference

12 December 2020

Platelet factor 4-induced neutrophil-endothelial cell interaction: involvement of mechanisms and functional consequences different from those elicited by interleukin-8

1 reference

12 December 2020

Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils

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12 December 2020

Actions and therapeutic potential of G-CSF and GM-CSF in cardiovascular disease

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12 December 2020

Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry

1 reference

12 December 2020

Potent antiviral synergy between monoclonal antibody and small-molecule CCR5 inhibitors of human immunodeficiency virus type 1

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12 December 2020

Potential role for Duffy antigen chemokine-binding protein in angiogenesis and maintenance of homeostasis in response to stress

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12 December 2020

Differential effects of stromal derived factor-1 alpha (SDF-1 alpha) on early and late stages of human megakaryocytic development

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12 December 2020

Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice

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12 December 2020

CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3.

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12 December 2020

Antimicrobial peptides from human platelets

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12 December 2020

Platelet factor 4 modulates the mitogenic activity of basic fibroblast growth factor

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12 December 2020

Induction and antimicrobial activity of platelet basic protein derivatives in human monocytes.

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12 December 2020

Modulation of the SDF-1-CXCR4 axis by the third complement component (C3)--implications for trafficking of CXCR4+ stem cells

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12 December 2020

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

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12 December 2020

Novel roles of osteopontin and CXC chemokine ligand 7 in the defence against mycobacterial infection.

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12 December 2020

Novel antiviral activity of chemokines

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12 December 2020

RGS16 is a negative regulator of SDF-1-CXCR4 signaling in megakaryocytes.

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12 December 2020

Immunocytochemical localization of the chemokines RANTES and MIP-1 alpha within human platelets and their release during storage.

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12 December 2020

TNF-alpha renders human neutrophils responsive to platelet factor 4. Comparison of PF-4 and IL-8 reveals different activity profiles of the two chemokines

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12 December 2020

Stromal cell-derived factor-1 (SDF-1) acts together with thrombopoietin to enhance the development of megakaryocytic progenitor cells (CFU-MK)

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12 December 2020

A chemokine-binding domain in the tumor necrosis factor receptor from variola (smallpox) virus

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12 December 2020

Inhibition of human umbilical vein endothelial cell proliferation by the CXC chemokine, platelet factor 4 (PF4), is associated with impaired downregulation of p21(Cip1/WAF1)

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12 December 2020

Platelet-derived CXC chemokines: old players in new games

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12 December 2020

Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration

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12 December 2020

Proteolysis by neutrophils. Relative importance of cell-substrate contact and oxidative inactivation of proteinase inhibitors in vitro

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12 December 2020

Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: determination of response to stromal-derived factor-1 by megakaryocytes and platelets

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12 December 2020

Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis.

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12 December 2020

Platelet microbicidal proteins and neutrophil defensin disrupt the Staphylococcus aureus cytoplasmic membrane by distinct mechanisms of action

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12 December 2020

Ticks produce highly selective chemokine binding proteins with antiinflammatory activity

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12 December 2020

Small peptide analogs to stromal derived factor-1 enhance chemotactic migration of human and mouse hematopoietic cells

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12 December 2020

CCR5: no longer a "good for nothing" gene--chemokine control of West Nile virus infection

1 reference

12 December 2020

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

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12 December 2020

A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.

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12 December 2020

Cleavage by CD26/dipeptidyl peptidase IV converts the chemokine LD78beta into a most efficient monocyte attractant and CCR1 agonist

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12 December 2020

Platelet factor 4 disrupts the intracellular signalling cascade induced by vascular endothelial growth factor by both KDR dependent and independent mechanisms.

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12 December 2020

Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor

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12 December 2020

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

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12 December 2020

Small-molecule antagonists for CXCR2 and CXCR1 inhibit human melanoma growth by decreasing tumor cell proliferation, survival, and angiogenesis

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12 December 2020

Neutralization of chemokines RANTES and MIG increases virus antigen expression and spinal cord pathology during Theiler's virus infection

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12 December 2020

Inhibition of Tat-mediated transactivation and HIV-1 replication by human anti-hCyclinT1 intrabodies

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12 December 2020

Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury

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12 December 2020

Chemokines as mediators of angiogenesis.

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12 December 2020

Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases

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12 December 2020

The functional role of the ELR motif in CXC chemokine-mediated angiogenesis

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12 December 2020

Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES

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12 December 2020

SDF-1alpha-mediated tissue repair by stem cells: a promising tool in cardiovascular medicine?

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12 December 2020

Structural basis of chemokine sequestration by a herpesvirus decoy receptor

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12 December 2020

Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome

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12 December 2020

Development of a systemically-active dual CXCR1/CXCR2 allosteric inhibitor and its efficacy in a model of transient cerebral ischemia in the rat.

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12 December 2020

VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells

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12 December 2020

Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium

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12 December 2020

Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1

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12 December 2020

Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease

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12 December 2020

The chemokine receptor D6 limits the inflammatory response in vivo

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12 December 2020

Thrombopoietin-induced CXC chemokines, NAP-2 and PF4, suppress polyploidization and proplatelet formation during megakaryocyte maturation

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12 December 2020

Effect of fast protein liquid chromatography fractionated salivary gland extracts from different ixodid tick species on interleukin-8 binding to its cell receptors

1 reference

12 December 2020

Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1.

1 reference

12 December 2020

Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium

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12 December 2020

Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways. Discrepancies in binding affinities, receptor densities, and biologic effects

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12 December 2020

Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

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12 December 2020

Viral exploitation and subversion of the immune system through chemokine mimicry

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12 December 2020

Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis

1 reference

12 December 2020

T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery.

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12 December 2020

Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils

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12 December 2020

Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells

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12 December 2020

Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC)

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12 December 2020

Human plasma proteinase inhibitors

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12 December 2020

Both interleukin-8 receptors independently mediate chemotaxis. Jurkat cells transfected with IL-8R1 or IL-8R2 migrate in response to IL-8, GRO alpha and NAP-2

1 reference

12 December 2020

SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10

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12 December 2020

Megakaryocyte maturation is associated with expression of the CXC chemokine connective tissue-activating peptide CTAP III.

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12 December 2020

The angiostatic activity of interferon-inducible protein-10/CXCL10 in human melanoma depends on binding to CXCR3 but not to glycosaminoglycan

1 reference

12 December 2020

Ca2+ i Changes and Respiratory Burst in Human Neutrophils and Monocytes Induced by NAP-1/Interleukin-8, NAP-2, and gro /MGSA

1 reference

12 December 2020

Tick saliva inhibits the chemotactic function of MIP-1α and selectively impairs chemotaxis of immature dendritic cells by down-regulating cell-surface CCR5

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12 December 2020

Activation of NK cells by CC chemokines. Chemotaxis, Ca2+ mobilization, and enzyme release

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12 December 2020

Structural requirements for interleukin-8 function identified by design of analogs and CXC chemokine hybrids

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12 December 2020

Constitutive and regulated expression of platelet basic protein in human monocytes

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12 December 2020

Purification and in vitro activities of rabbit platelet microbicidal proteins.

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12 December 2020

Platelet factor-4 inhibits the mitogenic activity of VEGF121 and VEGF165 using several concurrent mechanisms

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12 December 2020

Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTES-dependent firm adhesion of leukocytes

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12 December 2020

Modular determinants of antimicrobial activity in platelet factor-4 family kinocidins

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12 December 2020

Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2.

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12 December 2020

Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies

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12 December 2020

Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes

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12 December 2020

Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

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12 December 2020

Platelet activation and atherothrombosis

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12 December 2020

Activation of the megakaryocyte-specific gene platelet basic protein (PBP) by the Ets family factor PU.1.

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12 December 2020

The CXC Chemokines Growth-regulated Oncogene (GRO) α, GROβ, GROγ, Neutrophil-activating Peptide-2, and Epithelial Cell-derived Neutrophil-activating Peptide-78 Are Potent Agonists for the Type B, but Not the Type A, Human Interleukin-8 Receptor

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12 December 2020

Negative regulation of human megakaryocytopoiesis by human platelet factor 4 and beta thromboglobulin: comparative analysis in bone marrow cultures from normal individuals and patients ...

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12 December 2020

Single-dose safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus protease inhibitor

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12 December 2020

Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity

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12 December 2020

Platelet factor 4 (PF-4)–induced neutrophil adhesion is controlled by src-kinases, whereas PF-4–mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase

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12 December 2020

Inhibition of CXCR2 signaling promotes recovery in models of multiple sclerosis

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12 December 2020

Monocyte-derived CXCL7 peptides in the marrow microenvironment

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12 December 2020

Viral chemokine-binding proteins inhibit inflammatory responses and aortic allograft transplant vasculopathy in rat models.

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12 December 2020

Proteoglycans on bone marrow endothelial cells bind and present SDF-1 towards hematopoietic progenitor cells

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12 December 2020

Structural requirements of platelet chemokines for neutrophil activation.

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12 December 2020

Nonpeptide CXCR2 antagonist prevents neutrophil accumulation in hyperoxia-exposed newborn rats.

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12 December 2020

ADP receptor antagonists inhibit platelet aggregation induced by the chemokines SDF-1, MDC and TARC.

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12 December 2020

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

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12 December 2020

The bicyclam AMD3100 story

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12 December 2020

A novel cleavage product of beta-thromboglobulin formed in cultures of stimulated mononuclear cells activates human neutrophils

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12 December 2020

IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis

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12 December 2020

The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2

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12 December 2020

Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis

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12 December 2020

Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes

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12 December 2020

Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G.

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12 December 2020

Neutrophil adhesion to endothelial cells induced by platelet factor 4 requires sequential activation of Ras, Syk, and JNK MAP kinases

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12 December 2020

Current status of gene therapy strategies to treat HIV/AIDS.

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12 December 2020

An antagonist of monocyte chemoattractant protein 1 (MCP-1) inhibits arthritis in the MRL-lpr mouse model

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12 December 2020

Receptor expression and responsiveness of human dendritic cells to a defined set of CC and CXC chemokines.

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12 December 2020

Virally encoded chemokine binding proteins.

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12 December 2020

Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation

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12 December 2020

Molecular cloning and characterization of a highly selective chemokine-binding protein from the tick Rhipicephalus sanguineus.

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12 December 2020

Chemokine and chemokine receptor mRNA expression in human platelets

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12 December 2020

Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response

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12 December 2020

Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity

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12 December 2020

A human inhibitor of tumor necrosis factor alpha

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12 December 2020

A chondroitin sulfate proteoglycan on human neutrophils specifically binds platelet factor 4 and is involved in cell activation

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12 December 2020

Efficacy and safety of a monoclonal antibody recognizing interleukin-8 in COPD: a pilot study.

1 reference

12 December 2020

The SDF-1-CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis

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12 December 2020

RANTES, a monocyte and T lymphocyte chemotactic cytokine releases histamine from human basophils

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12 December 2020

Molecular mimicry of a CCR5 binding-domain in the microbial activation of dendritic cells

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12 December 2020

Low-molecular-weight fucoidan promotes therapeutic revascularization in a rat model of critical hindlimb ischemia

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12 December 2020

Stimulation of angiostatic platelet factor-4 variant (CXCL4L1/PF-4var) versus inhibition of angiogenic granulocyte chemotactic protein-2 (CXCL6/GCP-2) in normal and tumoral mesenchymal cells

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12 December 2020

PF-4/CXCL4 and CXCL4L1 exhibit distinct subcellular localization and a differentially regulated mechanism of secretion

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12 December 2020

Chemokine regulation of human megakaryocytopoiesis

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12 December 2020

Chemokines on the move: control by the chemokine "interceptors" Duffy blood group antigen and D6.

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12 December 2020

Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

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12 December 2020

Regulated expression of platelet factor 4 in human monocytes--role of PARs as a quantitatively important monocyte activation pathway

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12 December 2020

Deletion of the murine Duffy gene (Dfy) reveals that the Duffy receptor is functionally redundant

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12 December 2020

The CXC chemokines, IL-8 and IP-10, regulate angiogenic activity in idiopathic pulmonary fibrosis.

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12 December 2020

Blockade of CXCL12/CXCR4 Axis Ameliorates Murine Experimental Colitis

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12 December 2020

The amino-terminal residues in the crystal structure of connective tissue activating peptide-III (des10) block the ELR chemotactic sequence

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12 December 2020

The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques.

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12 December 2020

Negative regulation of human megakaryocytopoiesis by human platelet factor 4 (PF4) and connective tissue-activating peptide (CTAP-III)

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12 December 2020

The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation

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12 December 2020

Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth.

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12 December 2020

Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet function

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12 December 2020

Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

1 reference

12 December 2020

Antiviral activity, pharmacokinetics and safety of vicriviroc, an oral CCR5 antagonist, during 14-day monotherapy in HIV-infected adults

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12 December 2020

Transcytosis and Surface Presentation of IL-8 by Venular Endothelial Cells

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12 December 2020

Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells.

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12 December 2020

Multi-faceted strategies to combat disease by interference with the chemokine system

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12 December 2020

Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211

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12 December 2020

Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines

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12 December 2020

Evidence for a granule targeting sequence within platelet factor 4.

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12 December 2020

Trends in the Development and Approval of Monoclonal Antibodies for Viral Infections

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12 December 2020

Antivirals become a broader enterprise

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12 December 2020

The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion.

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12 December 2020

Platelets secrete stromal cell-derived factor 1alpha and recruit bone marrow-derived progenitor cells to arterial thrombi in vivo

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12 December 2020

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

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12 December 2020

Leukocyte-derived growth factor links the PDGF and CXC chemokine families of peptides

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12 December 2020

Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii.

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12 December 2020

Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils

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12 December 2020

A synthetic, non-peptide CXCR2 antagonist blocks MIP-2-induced neutrophil migration in mice

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12 December 2020

Chemokine receptors: multifaceted therapeutic targets

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12 December 2020

Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system

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12 December 2020

Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

1 reference

12 December 2020

Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4

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12 December 2020

IGF2 modulates the microenvironment for osteoclastogenesis

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12 December 2020

Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium

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12 December 2020

Platelet factor 4 inhibits proliferation and cytokine release of activated human T cells

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12 December 2020

International union of pharmacology. XXII. Nomenclature for chemokine receptors

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12 December 2020

CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.

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12 December 2020

Platelets and chemokines in atherosclerosis: partners in crime

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12 December 2020

Platelet factor 4 binds to interleukin 8 receptors and activates neutrophils when its N terminus is modified with Glu-Leu-Arg.

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12 December 2020

Stromal cell-derived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization

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12 December 2020

The role of CXC chemokines and their receptors in cancer.

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12 December 2020

Viral mimicry of cytokines, chemokines and their receptors

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12 December 2020

Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III

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12 December 2020

Platelet factor 4 modulates fibroblast growth factor 2 (FGF-2) activity and inhibits FGF-2 dimerization

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12 December 2020

Complete covalent structure of human beta-thromboglobulin

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12 December 2020

Platelets: signaling cells in the immune continuum.

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12 December 2020

Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa.

1 reference

12 December 2020

Therapeutic potential of the chemokine receptor CXCR4 antagonists as multifunctional agents.

1 reference

12 December 2020

Recombinant human granulocyte-colony-stimulating factor-mobilized and apheresis-collected endothelial progenitor cells: a novel blood cell component for therapeutic vasculogenesis

1 reference

12 December 2020

Mast cells: multipotent local effector cells in atherothrombosis

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12 December 2020

Occurrence of platelet basic protein, a precursor of low affinity platelet factor 4 and beta-thromboglobulin, in human platelets and megakaryocytes

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12 December 2020

HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211.

1 reference

12 December 2020

Differential role of platelet granular mediators in angiogenesis

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12 December 2020

Platelet factor-4 variant chemokine CXCL4L1 inhibits melanoma and lung carcinoma growth and metastasis by preventing angiogenesis.

1 reference

12 December 2020

Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets.

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12 December 2020

Differential response of platelets to chemokines: RANTES non-competitively inhibits stimulatory effect of SDF-1 alpha

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12 December 2020

The effects of human recombinant MIP-1 alpha, MIP-1 beta, and RANTES on the chemotaxis and adhesion of T cell subsets

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12 December 2020

Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartments.

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12 December 2020

Cancer-related inflammation

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12 December 2020

Interferon-gamma-inducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases

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12 December 2020

Viral chemokine-binding proteins

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12 December 2020

Posttranslational processing of chemokines

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12 December 2020

Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity

1 reference

12 December 2020

CXCR2 antagonists for the treatment of pulmonary disease

1 reference

12 December 2020

Importance of recruitment of bone marrow-derived CXCR4+ cells in post-infarct cardiac repair mediated by G-CSF

1 reference

12 December 2020

Can gene delivery close the door to HIV-1 entry after escape?

1 reference

12 December 2020

Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury

1 reference

12 December 2020

Differential and additive effects of platelet-derived chemokines on monocyte arrest on inflamed endothelium under flow conditions

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12 December 2020

Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques

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12 December 2020

The CXC-chemokine CXCL4 interacts with integrins implicated in angiogenesis

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12 December 2020

CCR5 small-molecule antagonists and monoclonal antibodies exert potent synergistic antiviral effects by cobinding to the receptor

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12 December 2020

RANTES and macrophage inflammatory protein 1 alpha induce the migration and activation of normal human eosinophil granulocytes

1 reference

12 December 2020

LD78beta, a non-allelic variant of human MIP-1alpha (LD78alpha), has enhanced receptor interactions and potent HIV suppressive activity

1 reference

12 December 2020

Gene transfer of virally encoded chemokine antagonists vMIP-II and MC148 prolongs cardiac allograft survival and inhibits donor-specific immunity.

1 reference

12 December 2020

Connective tissue-activating peptide III desensitizes chemokine receptors on neutrophils. Requirement for proteolytic formation of the neutrophil-activating peptide 2

1 reference

12 December 2020

The Duffy antigen/receptor for chemokines (DARC) regulates prostate tumor growth

1 reference

12 December 2020

LDL oxidized by hypochlorous acid causes irreversible platelet aggregation when combined with low levels of ADP, thrombin, epinephrine, or macrophage-derived chemokine (CCL22).

1 reference

12 December 2020

DAMPs, PAMPs and alarmins: all we need to know about danger

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12 December 2020

IFN-gamma-inducible protein-10 attenuates bleomycin-induced pulmonary fibrosis via inhibition of angiogenesis

1 reference

12 December 2020

The CC chemokines MDC and TARC induce platelet activation via CCR4

1 reference

12 December 2020

Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor

1 reference

12 December 2020

10.1007/S00018-010-0306-X

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20213276