Novel interfering bifunctional molecules against the CCR5 coreceptor are efficient inhibitors of HIV-1 infection (Q40639381)

22 September 2017

Novel interfering bifunctional molecules against the CCR5 coreceptor are efficient inhibitors of HIV-1 infection (English)

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22 September 2017

José Luis Abad

1

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22 September 2017

Manuel A González

2

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22 September 2017

Gustavo del Real

3

1 reference

22 September 2017

Emilia Mira

4

1 reference

22 September 2017

Santos Mañes

5

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22 September 2017

Fernando Serrano

6

1 reference

22 September 2017

Antonio Bernad

7

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22 September 2017

1 September 2003

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22 September 2017

1 reference

22 September 2017

8

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22 September 2017

475-484

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22 September 2017

3

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Chemokine receptors: keys to AIDS pathogenesis?

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cells

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Susceptibility of in vitro stimulated PBMC to infection with NSI HIV-1 is associated with levels of CCR5 expression and beta-chemokine production

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Human adipose cells express CD4, CXCR4, and CCR5 [corrected] receptors: a new target cell type for the immunodeficiency virus-1?

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

The role of CC chemokine receptor 5 in antiviral immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

HIV blocked by chemokine antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Approaches to gene therapy for human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Blockade of human immunodeficiency virus type 1 production in CD4+ T cells by an intracellular CD4 expressed under control of the viral long terminal repeat

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Inactivation of HIV-1 chemokine co-receptor CXCR-4 by a novel intrakine strategy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Genetic co-inactivation of macrophage- and T-tropic HIV-1 chemokine coreceptors CCR-5 and CXCR-4 by intrakines

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Inhibition of HIV-1 infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Phenotypic knockout of HIV type 1 chemokine coreceptor CCR-5 by intrakines as potential therapeutic approach for HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Sequence specific cleavage of the HIV-1 coreceptor CCR5 gene by a hammer-head ribozyme and a DNA-enzyme: inhibition of the coreceptor function by DNA-enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Anti-HIV type 1 activity of wild-type and functional defective RANTES intrakine in primary human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Inhibition of CCR5-dependent HIV-1 infection by hairpin ribozyme gene therapy against CC-chemokine receptor 5.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Characterization of anti-CCR5 ribozyme-transduced CD34+ hematopoietic progenitor cells in vitro and in a SCID-hu mouse model in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Downregulation of the CCR5 beta-chemokine receptor and inhibition of HIV-1 infection by stable VA1-ribozyme chimeric transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Multivalent anti-CCR ribozymes for stem cell-based HIV type 1 gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

siRNA-directed inhibition of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Determinants of the trans-dominant negative effect of truncated forms of the CCR5 chemokine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Human chemokines: an update

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

A hammerhead ribozyme targeted to the human chemokine receptor CCR5.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

A role for chemokine receptor transactivation in growth factor signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

HIV-1 infection in individuals with the CCR5-Delta32/Delta32 genotype: acquisition of syncytium-inducing virus at seroconversion

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Reduced cell surface expression of CCR5 in CCR5Delta 32 heterozygotes is mediated by gene dosage, rather than by receptor sequestration

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Retrovirus-mediated gene transfer into T cells: 95% transduction efficiency without further in vitro selection

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

Intrakines--evidence for a trans-cellular mechanism of action

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

A mechanism of resistance to HIV-1 entry: inefficient interactions of CXCR4 with CD4 and gp120 in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

CD4 T cell surface CCR5 density as a host factor in HIV-1 disease progression.

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use

1 reference

https://api.crossref.org/works/10.1016%2FS1525-0016%2803%2900202-8

7 January 2021

10.1016/S1525-0016(03)00202-8

Identifiers

DOI

1 reference

22 September 2017

1 reference