2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease (Q37698596)

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26 February 2020

title

2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease (English)

1 reference

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26 February 2020

0 references

12

1 reference

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26 February 2020

Alejandra Gallardo-Godoy

6

1 reference

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26 February 2020

Matthew P. Jacobson

10

1 reference

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26 February 2020

11

Stanley B Prusiner

1 reference

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26 February 2020

author name string

Zhe Li

1

1 reference

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26 February 2020

B Michael Silber

2

1 reference

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26 February 2020

Satish Rao

3

1 reference

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26 February 2020

Joel R Gever

4

1 reference

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26 February 2020

Clifford Bryant

5

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26 February 2020

Elena Dolghih

7

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26 February 2020

Kartika Widjaja

8

1 reference

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26 February 2020

Manuel Elepano

9

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26 February 2020

publication date

18 March 2013

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26 February 2020

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26 February 2020

volume

8

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26 February 2020

issue

5

1 reference

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26 February 2020

page(s)

847-857

1 reference

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Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice

26 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Predicting binding to p-glycoprotein by flexible receptor docking

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Discovery of 6-substituted indole-3-glyoxylamides as lead antiprion agents with enhanced cell line activity, improved microsomal stability and low toxicity.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

2-Aminothiazoles as therapeutic leads for prion diseases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Discovery of 2-aminothiazoles as potent antiprion compounds

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Getting a grip on prions: oligomers, amyloids, and pathological membrane interactions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Molecular mechanisms of prion pathogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Library synthesis and screening: 2,4-diphenylthiazoles and 2,4-diphenyloxazoles as potential novel prion disease therapeutics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Structure-brain exposure relationships

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

A chimeric ligand approach leading to potent antiprion active acridine derivatives: design, synthesis, and biological investigations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

The controversial protein-only hypothesis of prion propagation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Emerging principles of conformation-based prion inheritance

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

New series of antiprion compounds: pyrazolone derivatives have the potent activity of inhibiting protease-resistant prion protein accumulation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

The anti-prion activity of Congo red. Putative mechanism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Cell biology. A unifying role for prions in neurodegenerative diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Efficient inhibition of prion replication by PrP-Fc(2) suggests that the prion is a PrP(Sc) oligomer.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Structural intermediates in the putative pathway from the cellular prion protein to the pathogenic form.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984044

Inhomogeneous Electron Gas

1 September 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300007

Self-Consistent Equations Including Exchange and Correlation Effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300007

Amyloid Fibrils of Mammalian Prion Protein Are Highly Toxic to Cultured Cells and Primary Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300007

A versatile method for Suzuki cross-coupling reactions of nitrogen heterocycles

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23509039

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Versatile Method for Suzuki Cross-Coupling Reactions of Nitrogen Heterocycles

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201300007

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/CMDC.201300007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23509039%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23509039%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

23509039

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23509039%20AND%20SRC:MED&resulttype=core&format=json