ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97. (Q37687114)

22 August 2017

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title

ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97. (English)

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22 August 2017

Masatoshi Esaki

1

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PubMed ID

20130684

22 August 2017

Teru Ogura

series ordinal

2

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22 August 2017

1 February 2010

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Biochemistry and Cell Biology

22 August 2017

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22 August 2017

88

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22 August 2017

1

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22 August 2017

109-117

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Spatial precision of a catalytic carboxylate of F1-ATPase beta subunit probed by introducing different carboxylate-containing side chains

22 August 2017

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The molecular architecture of the metalloprotease FtsH.

21 January 2018

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Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase

21 January 2018

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Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

21 January 2018

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Conformational changes of p97 during nucleotide hydrolysis determined by small-angle X-Ray scattering

21 January 2018

1 reference

Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change

21 January 2018

1 reference

Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains

21 January 2018

1 reference

Nucleotide dependent motion and mechanism of action of p97/VCP

21 January 2018

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Central pore residues mediate the p97/VCP activity required for ERAD

21 January 2018

1 reference

Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression

21 January 2018

1 reference

VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death

21 January 2018

1 reference

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

21 January 2018

1 reference

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

21 January 2018

1 reference

Dissecting the role of a conserved motif (the second region of homology) in the AAA family of ATPases. Site-directed mutagenesis of the ATP-dependent protease FtsH.

21 January 2018

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Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells

21 January 2018

1 reference

The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97

21 January 2018

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Identification of yeast MAS17 encoding the functional counterpart of the mitochondrial receptor complex protein MOM22 of Neurospora crassa.

21 January 2018

1 reference

p97 Homologs from Caenorhabditis elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat

21 January 2018

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Cloning, sequencing and expression of VAT, a CDC48/p97 ATPase homologue from the archaeon Thermoplasma acidophilum.

21 January 2018

1 reference

TER94, a Drosophila homolog of the membrane fusion protein CDC48/p97, is accumulated in nonproliferating cells: in the reproductive organs and in the brain of the imago.

21 January 2018

1 reference

AAA+ proteins: diversity in function, similarity in structure

21 January 2018

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ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity

21 January 2018

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Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways

21 January 2018

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Structure of the whole cytosolic region of ATP-dependent protease FtsH.

21 January 2018

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Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities

21 January 2018

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D1 ring is stable and nucleotide-independent, whereas D2 ring undergoes major conformational changes during the ATPase cycle of p97-VCP.

21 January 2018

1 reference

Multifunctional roles of the conserved Arg residues in the second region of homology of p97/valosin-containing protein

21 January 2018

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Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

21 January 2018

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Novel VCP mutations in inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia.

21 January 2018

1 reference

Valosin-containing protein disease: inclusion body myopathy with Paget's disease of the bone and fronto-temporal dementia

21 January 2018

1 reference

AAA+ ATPases: achieving diversity of function with conserved machinery

21 January 2018

1 reference

Mutational analysis of the functional motifs in the ATPase domain of Caenorhabditis elegans fidgetin homologue FIGL-1: firm evidence for an intersubunit catalysis mechanism of ATP hydrolysis by AAA ATPases

21 January 2018

1 reference

Conserved Pore Residues in the AAA Protease FtsH Are Important for Proteolysis and Its Coupling to ATP Hydrolysis

21 January 2018

1 reference

Analysis of the two p97/VCP/Cdc48p proteins of Caenorhabditis elegans and their suppression of polyglutamine-induced protein aggregation.

21 January 2018

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Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase

21 January 2018

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Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1139/O09-116

1 reference

22 August 2017

1 reference

PubMed ID

20130684