The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells. (Q37683384)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24532803%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells (English)

1 reference

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8 March 2020

0 references

7

1 reference

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8 March 2020

Sumit Sahni

1

1 reference

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8 March 2020

Dong-Hun Bae

2

1 reference

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8 March 2020

Darius Lane

3

1 reference

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8 March 2020

Danuta S Kalinowski

5

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8 March 2020

6

Patric J Jansson

1 reference

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8 March 2020

4

Zaklina Kovacevic

1 reference

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8 March 2020

language of work or name

English

0 references

publication date

15 February 2014

1 reference

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Journal of Biological Chemistry

8 March 2020

published in

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8 March 2020

volume

289

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8 March 2020

page(s)

9692-9709

1 reference

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8 March 2020

issue

14

1 reference

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Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress

8 March 2020

cites work

1 reference

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N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.

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NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states

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23 August 2017

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Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.

23 August 2017

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6 September 2017

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Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway

6 September 2017

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6 September 2017

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The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways

6 September 2017

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The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).

6 September 2017

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6 September 2017

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6 September 2017

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Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer

6 September 2017

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N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo

6 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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NDRG1 is necessary for p53-dependent apoptosis

14 September 2017

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Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation

14 September 2017

1 reference

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The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc

14 September 2017

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Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

14 September 2017

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The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydra

28 September 2017

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N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

28 September 2017

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23 June 2018

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23 June 2018

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The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms.

23 June 2018

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The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation: an EPR study.

1 September 2018

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ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

1 September 2018

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N-myc down-regulated gene 1 modulates the response of term human trophoblasts to hypoxic injury.

1 September 2018

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Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes

1 September 2018

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Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction.

1 September 2018

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Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment.

1 September 2018

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1 September 2018

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Caspases as key executors of methyl selenium-induced apoptosis (anoikis) of DU-145 prostate cancer cells

1 September 2018

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Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24532803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of differentiation-related genes in colorectal cancer: possible implications for prognosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24532803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M113.529511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24532803%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24532803%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference