An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage (Q37680382)

21 August 2017

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage (English)

1 reference

21 August 2017

1 reference

Charles L Zhao

3

0 references

Eli J Fine

object named as

Eli J Fine

1

0 references

Thomas J. Cradick

object named as

Thomas J Cradick

2

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author name string

Yanni Lin

4

1 reference

21 August 2017

Gang Bao

5

1 reference

21 August 2017

language of work or name

English

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publication date

30 December 2013

1 reference

21 August 2017

Nucleic Acids Research

1 reference

21 August 2017

42

1 reference

21 August 2017

6

1 reference

21 August 2017

e42

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

21 August 2017

start time

11 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

SAPTA: a new design tool for improving TALE nuclease activity

1 reference

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TALENoffer: genome-wide TALEN off-target prediction

23 August 2017

1 reference

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In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites

23 August 2017

1 reference

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CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

23 August 2017

1 reference

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DNA targeting specificity of RNA-guided Cas9 nucleases

23 August 2017

1 reference

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

23 August 2017

1 reference

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TALEN-based gene correction for epidermolysis bullosa.

23 August 2017

1 reference

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Quantitative analysis of TALE-DNA interactions suggests polarity effects.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

A TALEN genome-editing system for generating human stem cell-based disease models

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Highly active zinc-finger nucleases by extended modular assembly

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Zinc-finger nuclease mediated disruption of Rag1 in the LEW/Ztm rat.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

23 August 2017

1 reference

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23 August 2017

1 reference

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In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Genetic engineering of human pluripotent cells using TALE nucleases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

A TALE nuclease architecture for efficient genome editing

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

A flexible and efficient template format for circular consensus sequencing and SNP detection

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

A simple cipher governs DNA recognition by TAL effectors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

The Genome of Black Cottonwood, Populus trichocarpa (Torr. & Gray)

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Chimeric nucleases stimulate gene targeting in human cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

The human genome browser at UCSC

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Primer3 on the WWW for general users and for biologist programmers

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

A general method applicable to the search for similarities in the amino acid sequence of two proteins

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

TAL effectors: customizable proteins for DNA targeting

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

An unbiased genome-wide analysis of zinc-finger nuclease specificity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Non-transgenic genome modifications in a hemimetabolous insect using zinc-finger and TAL effector nucleases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

TALENs and ZFNs are associated with different mutation signatures

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Heritable gene targeting in zebrafish using customized TALENs.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Knockout rats generated by embryo microinjection of TALENs.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

Genome sequences of Escherichia coli B strains REL606 and BL21(DE3).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3973315

TAL effector RVD specificities and efficiencies

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24381193

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKT1326

1 reference

release_twrcjsnkbfcbbpxbcnnklh7bbi

21 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/twrcjsnkbfcbbpxbcnnklh7bbi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

21 August 2017

1 reference