Pulsatility of insulin release--a clinically important phenomenon (Q37644482)

21 August 2017

2 references

17 November 2019

20 November 2019

Pulsatility of insulin release--a clinically important phenomenon (English)

1 reference

21 August 2017

1 reference

17 November 2019

1 reference

20 November 2019

1 reference

Bo Hellman

1

1 reference

21 August 2017

1 January 2009

1 reference

Upsala Journal of Medical Sciences

21 August 2017

3 references

21 August 2017

17 November 2019

20 November 2019

114

1 reference

21 August 2017

4

1 reference

21 August 2017

193-205

1 reference

Creative Commons Attribution 2.5 Generic

21 August 2017

2 references

17 November 2019

Synchronization of pancreatic islet oscillations by intrapancreatic ganglia: a modeling study

20 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Pulsatile intravenous insulin therapy: the best practice to reverse diabetes complications?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

P2 purinergic signalling in the pancreatic beta-cell: control of insulin secretion and pharmacology

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

The incretin system and its role in type 2 diabetes mellitus

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Oscillatory control of insulin secretion

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

On high-frequency insulin oscillations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

The unique cytoarchitecture of human pancreatic islets has implications for islet cell function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Pulsatile insulin secretion: detection, regulation, and role in diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Chronic intermittent intravenous insulin therapy: a new frontier in diabetes therapy

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Exploring complex networks

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Autonomic regulation of islet hormone secretion--implications for health and disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

The Patch Clamp Technique

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Pulses of external ATP aid to the synchronization of pancreatic beta-cells by generating premature Ca(2+) oscillations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Pancreatic beta-cells communicate via intermittent release of ATP.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Pancreatic beta-cells from obese-hyperglycemic mice are characterized by excessive firing of cytoplasmic Ca2+ transients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Propagation of cytoplasmic Ca2+ oscillations in clusters of pancreatic beta-cells exposed to glucose.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Glucose sensing of individual pancreatic beta-cells involves transitions between steady-state and oscillatory cytoplasmic Ca2+

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Glucose and insulin synergistically activate phosphatidylinositol 3-kinase to trigger oscillations of phosphatidylinositol 3,4,5-trisphosphate in beta-cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Insulin-secreting INS-1 cells generate a novel type of poorly synchronized Ca2+ transients

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Sustained oscillations of insulin, glucagon, and somatostatin from the isolated canine pancreas during exposure to a constant glucose concentration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Possible Roles of the Pancreatic D-cell in the Normal and Diabetic States

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Amino acid transformation of oscillatory Ca2+ signals in mouse pancreatic beta-cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Temporal patterns of changes in ATP/ADP ratio, glucose 6-phosphate and cytoplasmic free Ca2+ in glucose-stimulated pancreatic beta-cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Ca2+ oscillations in pancreatic islet cells secreting glucagon and somatostatin

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Role of intrapancreatic ganglia in regulation of periodic insular secretions

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Superior efficacy of pulsatile versus continuous hormone exposure on hepatic glucose production in vitro

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Effects of pulsatile delivery of insulin and glucagon in humans.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

A kinetic analysis of hepatocyte responses to a glucagon pulse: mechanism and metabolic consequences of differences in response decay times.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Actual Distribution of the Number and Volume of the Islets of Langerhans in Different Size Classes in Non-diabetic Humans of Varying Ages

25 June 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Synchronization of pancreatic beta-cell rhythmicity after glucagon induction of Ca2+ transients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Glucose-stimulated oscillations in free cytosolic ATP concentration imaged in single islet beta-cells: evidence for a Ca2+-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Absence of adenosine A1 receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Nitric oxide induces synchronous Ca2+ transients in pancreatic beta cells lacking contact

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Disorganization of cytoplasmic Ca(2+) oscillations and pulsatile insulin secretion in islets from ob/ obmice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Inhibition of purinoceptors amplifies glucose-stimulated insulin release with removal of its pulsatility

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

The mass, but not the frequency, of insulin secretory bursts in isolated human islets is entrained by oscillatory glucose exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Intraislet somatostatin inhibits insulin (via a subtype-2 somatostatin receptor) but not islet amyloid polypeptide secretion in the isolated perfused human pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Variations in ATP-sensitive K+ channel activity provide evidence for inherent metabolic oscillations in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Rapid oscillations in plasma insulin, glucagon, and glucose in obese and normal weight humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Intrahepatic transplanted islets in humans secrete insulin in a coordinate pulsatile manner directly into the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Glucose generates coincident insulin and somatostatin pulses and antisynchronous glucagon pulses from human pancreatic islets

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852781

Glucose-induced decrease in Rb+ permeability in pancreatic β cells

1 September 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Glucose Induces Opposite Intracellular Ca2+Concentration Oscillatory Patterns in Identified α- and β-Cells Within Intact Human Islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03009730903366075

Pulsatile, synchronous basal insulin and glucagon secretion in man

21 January 2018

1 reference

12 December 2020

Pulsatile Insulin Has Greater Hypoglycemic Effect Than Continuous Delivery

1 reference

12 December 2020

Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes

1 reference

12 December 2020

Phospholipase A2 is important for glucose induction of rhythmic Ca2+ signals in pancreatic beta cells

1 reference

12 December 2020

Synchronous oscillations of cytoplasmic Ca2+ and insulin release in glucose-stimulated pancreatic islets

1 reference

12 December 2020

Crosstalk between the cAMP and inositol trisphosphate-signalling pathways in pancreatic beta-cells

1 reference

12 December 2020

Are metabolic oscillations responsible for normal oscillatory insulin secretion?

1 reference

12 December 2020

Voltage-dependent entry and generation of slow Ca2+ oscillations in glucose-stimulated pancreatic beta-cells

1 reference

12 December 2020

Glucose and tolbutamide trigger transients of Ca2+ in single pancreatic beta-cells exposed to tetraethylammonium

1 reference

12 December 2020

The diabetogenic effect of alloxan after elimination of extra-pancreatic factors

1 reference

12 December 2020

Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels

1 reference

12 December 2020

Pulses of somatostatin release are slightly delayed compared with insulin and antisynchronous to glucagon

1 reference

12 December 2020

Beta-cell cytoplasmic Ca2+ balance as a determinant for glucose-stimulated insulin release

1 reference

12 December 2020

In vivo pulsatility of pancreatic islet peptides

1 reference

12 December 2020

Glucose-induced oscillations of cytoplasmic Ca2+ in the pancreatic beta-cell

1 reference

12 December 2020

Three types of cytoplasmic Ca2+ oscillations in stimulated pancreatic beta-cells

1 reference

12 December 2020

The cytoplasmic Ca2+ response to glucose as an indicator of impairment of the pancreatic beta-cell function

1 reference

12 December 2020

Pulsatile insulin delivery has greater metabolic effects than continuous hormone administration in man: importance of pulse frequency

1 reference

12 December 2020

The vascular order of islet cellular perfusion in the human pancreas

1 reference

12 December 2020

Glucose induces glucagon release pulses antisynchronous with insulin and sensitive to purinoceptor inhibition

1 reference

12 December 2020

Ca2+ signaling in mouse pancreatic polypeptide cells

1 reference

12 December 2020

Effects of pulsatile intravenous insulin therapy on the progression of diabetic nephropathy

1 reference

12 December 2020

Biological rhythms and the behavior of populations of coupled oscillators

1 reference

12 December 2020

Calcium and secretion: distinction between two pools of glucose-sensitive calcium in pancreatic islets

1 reference

12 December 2020

10.3109/03009730903366075

Identifiers

DOI

1 reference

21 August 2017

1 reference

PMC publication ID

2852781

21 August 2017

PubMed publication ID

19961265

1 reference

PMC publication ID

2852781