Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal. (Q37625585)

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scientific article published on December 1995

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English	Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.	scientific article published on December 1995

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scholarly article

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20 October 2019

Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal (English)

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20 October 2019

apoptotic process

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phosphatidylcholines

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based on heuristic

inferred from title

Maria Grazia Cifone

1

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20 October 2019

Giovina Ruberti

6

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20 October 2019

author name string

P Roncaioli

2

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20 October 2019

R De Maria

3

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20 October 2019

G Camarda

4

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A Santoni

5

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20 October 2019

R Testi

7

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20 October 2019

language of work or name

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publication date

1 December 1995

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20 October 2019

The EMBO Journal

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20 October 2019

14

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20 October 2019

5859-5868

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20 October 2019

23

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20 October 2019

cPLA2 is phosphorylated and activated by MAP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

23 August 2017

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway

1 reference

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The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

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The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

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23 August 2017

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

23 August 2017

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

23 August 2017

FAP-1: a protein tyrosine phosphatase that associates with Fas

1 reference

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23 August 2017

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

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23 August 2017

The role of APO-1-mediated apoptosis in the immune system

1 reference

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23 August 2017

The Fas death factor

1 reference

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23 August 2017

Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions

1 reference

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Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

1 reference

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Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes

1 reference

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23 August 2017

Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha

1 reference

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A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

1 reference

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23 August 2017

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

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23 August 2017

Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0

1 reference

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23 August 2017

Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60 cells

1 reference

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6 September 2017

Sphingomyelinase activates proteolytic I kappa B-alpha degradation in a cell-free system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

6 September 2017

Tumor necrosis factor receptor-mediated signaling pathways

1 reference

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14 September 2017

Fas and Fas ligand: lpr and gld mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

14 September 2017

Sphingomyelinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

28 September 2017

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

1 reference

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28 September 2017

Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

28 September 2017

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1 reference

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28 September 2017

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

28 September 2017

Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

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A novel domain within the 55 kd TNF receptor signals cell death

1 reference

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25 June 2018

Ceramide activates heterotrimeric protein phosphatase 2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

25 June 2018

Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

25 June 2018

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

25 June 2018

Fas antigen and p55 TNF receptor signal apoptosis through distinct pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

25 June 2018

Fas transduces activation signals in normal human T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

25 June 2018

1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

25 June 2018

Acid sphingomyelinase from human urine: purification and characterization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

25 June 2018

Activation interferes with the APO-1 pathway in mature human T cells.

1 reference

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1 September 2018

Programmed cell death and Bcl-2 protection in very low oxygen.

1 reference

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1 September 2018

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

1 September 2018

Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394704

1 September 2018

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

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TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death induced by ceramide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characteristics and partial purification of a novel cytosolic, magnesium-independent, neutral sphingomyelinase activated in the early signal transduction of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas-based lymphocyte-mediated cytotoxicity against syngeneic activated lymphocytes: a regulatory pathway?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8846779

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1995.TB00274.X

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20 October 2019

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20 October 2019

1 reference

Europe PubMed Central

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20 October 2019

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