U1A regulates 3' processing of the survival motor neuron mRNA. (Q37563561)

21 August 2017

U1A regulates 3' processing of the survival motor neuron mRNA. (English)

1 reference

21 August 2017

Eileen Workman

1

1 reference

21 August 2017

Alex Veith

series ordinal

2

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21 August 2017

Daniel J Battle

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

20 December 2013

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Journal of Biological Chemistry

21 August 2017

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21 August 2017

289

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21 August 2017

6

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21 August 2017

3703-3712

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describes a project that uses

21 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3916568/fullTextXML

inferred from PubMed Central ID database lookup

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Determinants within an 18-Amino-Acid U1A Autoregulatory Domain That Uncouple Cooperative RNA Binding, Inhibition of Polyadenylation, and Homodimerization

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23 August 2017

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23 August 2017

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The NMR structure of the 38 kDa U1A protein - PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein

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23 August 2017

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A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

23 August 2017

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23 August 2017

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The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor

23 August 2017

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Intragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number.

23 August 2017

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The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

23 August 2017

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The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

23 August 2017

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Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

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Survival motor neuron gene transcript analysis in muscles from spinal muscular atrophy patients.

23 August 2017

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The U1 RNA-binding site of the U1 small nuclear ribonucleoprotein (snRNP)-associated A protein suggests a similarity with U2 snRNPs

23 August 2017

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Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3916568

Spliceosomal small nuclear ribonucleoprotein biogenesis defects and motor neuron selectivity in spinal muscular atrophy

23 August 2017

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Biogenesis of spliceosomal small nuclear ribonucleoproteins

6 September 2017

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The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA.

6 September 2017

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Regulation of nuclear poly(A) addition controls the expression of immunoglobulin M secretory mRNA.

6 September 2017

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A bipartite U1 site represses U1A expression by synergizing with PIE to inhibit nuclear polyadenylation.

14 September 2017

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The snRNP-associated U1A levels change following IL-6 stimulation of human B-cells

14 September 2017

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U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts

14 September 2017

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U1A inhibits cleavage at the immunoglobulin M heavy-chain secretory poly(A) site by binding between the two downstream GU-rich regions

14 September 2017

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Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

28 September 2017

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A complex secondary structure in U1A pre-mRNA that binds two molecules of U1A protein is required for regulation of polyadenylation

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Reduced U snRNP assembly causes motor axon degeneration in an animal model for spinal muscular atrophy

25 June 2018

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U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase.

25 June 2018

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25 June 2018

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A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation

25 June 2018

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Sequences adjacent to the 5' splice site control U1A binding upstream of the IgM heavy chain secretory poly(A) site.

25 June 2018

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A multiprotein complex mediates the ATP-dependent assembly of spliceosomal U snRNPs

1 September 2018

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The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase

1 September 2018

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https://api.crossref.org/works/10.1074%2FJBC.M113.538264

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21 January 2018

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A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs

21 January 2018

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12 December 2020

Very severe spinal muscular atrophy (SMA type 0): an expanding clinical phenotype

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12 December 2020

Genetic basis of adult-onset spinal muscular atrophy

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AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation

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12 December 2020

International SMA consortium meeting. (26-28 June 1992, Bonn, Germany)

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12 December 2020

Spinal muscular atrophy: the RNP connection

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12 December 2020

Purification of functional RNA-protein complexes using MS2-MBP

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12 December 2020

A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy

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12 December 2020

Identifiers

DOI

10.1074/JBC.M113.538264

1 reference

21 August 2017

1 reference

21 August 2017

1 reference