U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. (Q47862801)

6 February 2018

title

U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase. (English)

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6 February 2018

author

Iain William Mattaj

series ordinal

3

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6 February 2018

author name string

Gunderson SI

series ordinal

1

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6 February 2018

Polycarpou-Schwarz M

series ordinal

2

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6 February 2018

publication date

1 January 1998

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6 February 2018

published in

Molecular Cell

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6 February 2018

volume

1

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6 February 2018

page(s)

255-264

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6 February 2018

issue

2

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6 February 2018

Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site

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The HIV-1 5' LTR poly(A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site.

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The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA.

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Regulation of poly(A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner

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Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions

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The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase

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Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation

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No end yet to messenger RNA 3' processing!

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Preparation and fractionation of mammalian extracts active in pre-mRNA splicing

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An intron enhancer recognized by splicing factors activates polyadenylation

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Ending the message is not so simple

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A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5' cleavage site.

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The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation

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The biochemistry of polyadenylation

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7 January 2021

A compensatory base change in U1 snRNA suppresses a 5' splice site mutation

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7 January 2021

10.1016/S1097-2765(00)80026-X

Identifiers

DOI

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6 February 2018

PubMed ID

9659922

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6 February 2018