The peptide-loading complex--antigen translocation and MHC class I loading. (Q37474825)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

review article

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title

The peptide-loading complex--antigen translocation and MHC class I loading (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Christian Schölz

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

Christian Schölz

series ordinal

1

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20 August 2017

1 August 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

volume

390

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

issue

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

page(s)

783-794

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner

27 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Human transporters associated with antigen processing possess a promiscuous peptide-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Stoichiometric tapasin interactions in the catalysis of major histocompatibility complex class I molecule assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The N-terminal region of tapasin is required to stabilize the MHC class I loading complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

ABC transporter architecture and regulatory roles of accessory domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A detailed analysis of the murine TAP transporter substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A Tweezers-like Motion of the ATP-Binding Cassette Dimer in an ABC Transport Cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Functional non-equivalence of ATP-binding cassette signature motifs in the transporter associated with antigen processing (TAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Peptides induce ATP hydrolysis at both subunits of the transporter associated with antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2009.069

ABC transporters: how small machines do a big job.

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2009.069

Structure of a bacterial multidrug ABC transporter

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2009.069

Complete characterization of the human ABC gene family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Disulfide bond isomerization and the assembly of MHC class I-peptide complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Insights into MHC Class I Peptide Loading from the Structure of the Tapasin-ERp57 Thiol Oxidoreductase Heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Effects of major-histocompatibility-complex-encoded subunits on the peptidase and proteolytic activities of human 20S proteasomes. Cleavage of proteins and antigenic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The human protein disulphide isomerase family: substrate interactions and functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

How does TAP associate with MHC class I molecules?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The optimization of peptide cargo bound to MHC class I molecules by the peptide-loading complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

ERp57 is a multifunctional thiol-disulfide oxidoreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

TROSY-NMR reveals interaction between ERp57 and the tip of the calreticulin P-domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Impaired immune responses and altered peptide repertoire in tapasin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Accessory molecules in the assembly of major histocompatibility complex class I/peptide complexes: how essential are they for CD8(+) T-cell immune responses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Structural basis of trans-inhibition in a molybdate/tungstate ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Allosteric crosstalk between peptide-binding, transport, and ATP hydrolysis of the ABC transporter TAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Tapasin: an ER chaperone that controls MHC class I assembly with peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The final touches make perfect the peptide-MHC class I repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Multiple membrane-cytoplasmic domain contacts in the cystic fibrosis transmembrane conductance regulator (CFTR) mediate regulation of channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Intracellular functions of N-linked glycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Roles of N-linked glycans in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Structure and mechanism of ABC transporter proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Structure of an ABC transporter in complex with its binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Tapasin enhances MHC class I peptide presentation according to peptide half-life

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Crystal structure of the ATP-binding subunit of an ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Subunit interactions in ABC transporters: towards a functional architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Distinct functions and cooperative interaction of the subunits of the transporter associated with antigen processing (TAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Biogenesis of functional antigenic peptide transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The proteasome and MHC class I antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Functional dissection of the transmembrane domains of the transporter associated with antigen processing (TAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The first N-terminal transmembrane helix of each subunit of the antigenic peptide transporter TAP is essential for independent tapasin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Translocation of long peptides by transporters associated with antigen processing (TAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line .220.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Evidence for successive peptide binding and quality control stages during MHC class I assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Cloning and functional characterization of a subunit of the transporter associated with antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Viral evasion of the MHC class I antigen-processing machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Functional expression and purification of the ABC transporter complex associated with antigen processing (TAP) in insect cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Selectivity of MHC-encoded peptide transporters from human, mouse and rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Analysis of the fine specificity of rat, mouse and human TAP peptide transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Kinetic analysis of peptide binding to the TAP transport complex: evidence for structural rearrangements induced by substrate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

TAP polymorphism does not influence transport of peptide variants in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Crystal structure of a catalytic intermediate of the maltose transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Structure of a pheromone receptor-associated MHC molecule with an open and empty groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Multiple residues in the transmembrane helix and connecting peptide of mouse tapasin stabilize the transporter associated with the antigen-processing TAP2 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A point mutation in HLA-A*0201 results in failure to bind the TAP complex and to present virus-derived peptides to CTL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Regulation of MHC class I assembly and peptide binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Tapasin and ERp57 form a stable disulfide-linked dimer within the MHC class I peptide-loading complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

An inward-facing conformation of a putative metal-chelate-type ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Identification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Viral proteins interfering with antigen presentation target the major histocompatibility complex class I peptide-loading complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The Structure of calnexin, an ER chaperone involved in quality control of protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Membrane topology of the transporter associated with antigen processing (TAP1) within an assembled functional peptide-loading complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Comparative molecular dynamics analysis of tapasin-dependent and -independent MHC class I alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Aggregate formation by ERp57-deficient MHC class I peptide-loading complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Recognition principle of the TAP transporter disclosed by combinatorial peptide libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Requirements for peptide binding to the human transporter associated with antigen processing revealed by peptide scans and complex peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Kinetics of the ATP hydrolysis cycle of the nucleotide-binding domain of Mdl1 studied by a novel site-specific labeling technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

How do ABC transporters drive transport?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A sequential model for peptide binding and transport by the transporters associated with antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Three-dimensional structure of transporter associated with antigen processing (TAP) obtained by single Particle image analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Formation of DNA repair intermediates and incision by the ATP-dependent UvrB-UvrC endonuclease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Flexibility in the ABC transporter MsbA: Alternating access with a twist

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Optimization of the MHC class I peptide cargo is dependent on tapasin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

To DRiP or not to DRiP: generating peptide ligands for MHC class I molecules from biosynthesized proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Making sense of mass destruction: quantitating MHC class I antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

Conformational flexibility of the MHC class I alpha1-alpha2 domain in peptide bound and free states: a molecular dynamics simulation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A molecular understanding of the catalytic cycle of the nucleotide-binding domain of the ABC transporter HlyB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

ERp57 does not require interactions with calnexin and calreticulin to promote assembly of class I histocompatibility molecules, and it enhances peptide loading independently of its redox activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2009.069

21 January 2018

Identifiers

DOI

10.1515/BC.2009.069

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19426129%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference