Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport (Q37463107)

20 August 2017

Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport (English)

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20 August 2017

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3

Jerrold M Olefsky

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20 August 2017

Kazuaki Ohtsubo

1

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20 August 2017

Mark Z Chen

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2

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20 August 2017

Jamey D Marth

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4

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20 August 2017

language of work or name

English

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publication date

14 August 2011

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20 August 2017

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20 August 2017

17

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20 August 2017

1067-1075

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20 August 2017

9

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https://scigraph.springernature.com/pub.10.1038/nm.2414

20 August 2017

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cites work

Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell

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Lipid receptors and islet function: therapeutic implications?

23 August 2017

1 reference

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Nuclear export-independent inhibition of Foxa2 by insulin

23 August 2017

1 reference

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Regulation of energy homeostasis and health consequences in obesity

23 August 2017

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Insulin sensitivity: modulation by nutrients and inflammation

23 August 2017

1 reference

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Mammalian galectins: structure, carbohydrate specificity, and functions

23 August 2017

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Mechanisms of disease: using genetically altered mice to study concepts of type 2 diabetes

23 August 2017

1 reference

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Glucolipotoxicity: fuel excess and beta-cell dysfunction.

23 August 2017

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Functions of cell surface galectin-glycoprotein lattices

23 August 2017

1 reference

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Mechanisms linking obesity to insulin resistance and type 2 diabetes

23 August 2017

1 reference

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Glycosylation in cellular mechanisms of health and disease

23 August 2017

1 reference

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Diabetes and obesity: the twin epidemics

23 August 2017

1 reference

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Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes

23 August 2017

1 reference

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The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

23 August 2017

1 reference

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The insulin resistance syndrome: definition and dietary approaches to treatment

23 August 2017

1 reference

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The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes

23 August 2017

1 reference

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Foxa2 regulates multiple pathways of insulin secretion.

23 August 2017

1 reference

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Diet composition and the risk of type 2 diabetes: epidemiological and clinical evidence

23 August 2017

1 reference

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The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

23 August 2017

1 reference

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The role of transcription factors in maturity-onset diabetes of the young

23 August 2017

1 reference

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IRS proteins and the common path to diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Insulin signalling and the regulation of glucose and lipid metabolism

23 August 2017

1 reference

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cDNA cloning and expression of bovine UDP-N-acetylglucosamine: alpha1, 3-D-mannoside beta1,4-N-acetylglucosaminyltransferase IV.

23 August 2017

1 reference

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Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Glucose-induced phosphorylation of the insulin receptor. Functional effects and characterization of phosphorylation sites

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Reduced beta-cell glucose transporter in new onset diabetic BB rats

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic rats

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Diabetic hyperglycemia: link to impaired glucose transport in pancreatic beta cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Mechanism of activation and function of protein kinase B.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Diet-induced type II diabetes in C57BL/6J mice

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Functional and molecular defects of pancreatic islets in human type 2 diabetes

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Variation in type 2 diabetes--related traits in mouse strains susceptible to diet-induced obesity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

Insulin treatment reverses the insulin resistance of type II diabetes mellitus.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3888087

The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2414

Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2414

Expression of GLUT-2 antisense RNA in beta cells of transgenic mice leads to diabetes

21 January 2018

1 reference

12 December 2020

Underexpression of beta cell high Km glucose transporters in noninsulin-dependent diabetes

1 reference

12 December 2020

Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells

1 reference

12 December 2020

Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels

1 reference

12 December 2020

Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion

1 reference

12 December 2020

Glucose uptake, utilization, and signaling in GLUT2-null islets

1 reference

12 December 2020

Lack of in Vivo Insulin Resistance in Controlled Insulin-Dependent, Type I, Diabetic Patients*

1 reference

12 December 2020

Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.2414

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.2414

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Dimensions Publication ID

20 August 2017

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20 August 2017

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