Bisphosphonates suppress insulin-like growth factor 1-induced angiogenesis via the HIF-1alpha/VEGF signaling pathways in human breast cancer cells (Q37441608)

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scientific article published on January 2010

Language	Label	Description	Also known as
English	Bisphosphonates suppress insulin-like growth factor 1-induced angiogenesis via the HIF-1alpha/VEGF signaling pathways in human breast cancer cells	scientific article published on January 2010

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Bisphosphonates suppress insulin-like growth factor 1-induced angiogenesis via the HIF-1alpha/VEGF signaling pathways in human breast cancer cells (English)

1 reference

Europe PubMed Central

20 August 2017

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Xudong Tang

1

1 reference

Europe PubMed Central

20 August 2017

Qunzhou Zhang

2

1 reference

Europe PubMed Central

20 August 2017

Shihong Shi

3

1 reference

Europe PubMed Central

20 August 2017

Yun Yen

4

1 reference

Europe PubMed Central

20 August 2017

Xiangyong Li

5

1 reference

Europe PubMed Central

20 August 2017

Yuefei Zhang

6

1 reference

Europe PubMed Central

20 August 2017

Keyuan Zhou

7

1 reference

Europe PubMed Central

20 August 2017

Anh D Le

8

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

1 January 2010

1 reference

Europe PubMed Central

20 August 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

International Journal of Cancer

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Europe PubMed Central

20 August 2017

126

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Europe PubMed Central

20 August 2017

1

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Europe PubMed Central

20 August 2017

90-103

1 reference

Europe PubMed Central

20 August 2017

Bidirectional crosstalk between leptin and insulin-like growth factor-I signaling promotes invasion and migration of breast cancer cells via transactivation of epidermal growth factor receptor

1 reference

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Hypoxia signalling through mTOR and the unfolded protein response in cancer

1 reference

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Bisphosphonates: mechanism of action and role in clinical practice

1 reference

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Paracrine overexpression of insulin-like growth factor-1 enhances mammary tumorigenesis in vivo

1 reference

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Emerging role of bisphosphonates in the clinic--antitumor activity and prevention of metastasis to bone

1 reference

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3,3'-diindolylmethane reduces levels of HIF-1alpha and HIF-1 activity in hypoxic cultured human cancer cells

1 reference

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Cancer statistics, 2008

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Disrupting insulin-like growth factor signaling as a potential cancer therapy

1 reference

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Hypoxia-inducible factor-1 in human breast and prostate cancer

1 reference

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1 reference

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23 August 2017

Bisphosphonates in breast cancer.

1 reference

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Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway

1 reference

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1 reference

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Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis

1 reference

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Targeting HIF-1 for cancer therapy

1 reference

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Bisphosphonates antagonise bone growth factors' effects on human breast cancer cells survival

1 reference

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Regulation of angiogenesis by hypoxia: role of the HIF system

1 reference

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In vitro and in vivo antitumor effects of bisphosphonates

1 reference

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Development of bisphosphonates

1 reference

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23 August 2017

Direct effects of bisphosphonates on breast cancer cells

1 reference

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Metastatic bone disease: clinical features, pathophysiology and treatment strategies

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Regulation of translation initiation by FRAP/mTOR

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

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1 reference

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Bisphosphonates induce apoptosis in human breast cancer cell lines

1 reference

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Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

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The IRS-signalling system: a network of docking proteins that mediate insulin action

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Fighting cancer by attacking its blood supply

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Bisphosphonates inhibit the adhesion of breast cancer cells to bone matrices in vitro

1 reference

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A RNA antagonist of hypoxia-inducible factor-1alpha, EZN-2968, inhibits tumor cell growth

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The bisphosphonate, zoledronic acid reduces experimental neuroblastoma growth by interfering with tumor angiogenesis

1 reference

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Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model

1 reference

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Cisplatin and doxorubicin repress Vascular Endothelial Growth Factor expression and differentially down-regulate Hypoxia-inducible Factor I activity in human ovarian cancer cells

1 reference

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Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer.

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Confluence-dependent resistance to doxorubicin in human MDA-MB-231 breast carcinoma cells requires hypoxia-inducible factor-1 activity

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Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1.

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Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway

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Bisphosphonates decrease telomerase activity and hTERT expression in MCF-7 breast cancer cells

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Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

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Bisphosphonates induce breast cancer cell death in vitro

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19569175

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https://pubmed.ncbi.nlm.nih.gov/19569175

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/19569175

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based on heuristic

inferred from PubMed ID database lookup

Overexpression of hypoxia-inducible factor HIF-1alpha predicts early relapse in breast cancer: retrospective study in a series of 745 patients

1 reference

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Identifiers

10.1002/IJC.24710

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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