Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells. (Q37399288)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19881958%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells (English)

1 reference

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11 February 2020

6

1 reference

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11 February 2020

Xuhong Qian

10

1 reference

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11 February 2020

Hong Zhu

1

0 references

author name string

Ze-Hong Miao

2

1 reference

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11 February 2020

Min Huang

3

1 reference

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11 February 2020

Jian-Ming Feng

4

1 reference

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11 February 2020

Zhi-Xiang Zhang

5

1 reference

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11 February 2020

Yu-Jun Cai

7

1 reference

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11 February 2020

Lin-Jiang Tong

8

1 reference

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11 February 2020

Yu-Fang Xu

9

1 reference

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11 February 2020

Jian Ding

11

1 reference

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11 February 2020

publication date

1 November 2009

1 reference

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11 February 2020

1 reference

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11 February 2020

volume

11

1 reference

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11 February 2020

page(s)

1226-1234

1 reference

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11 February 2020

issue

11

1 reference

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Naphthalimides and azonafides as promising anti-cancer agents

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767224

UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers

6 September 2017

1 reference

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Targeted cancer therapies based on the inhibition of DNA strand break repair

6 September 2017

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CHK2 kinase: cancer susceptibility and cancer therapy - two sides of the same coin?

6 September 2017

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Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: a Princess Margaret Hospital Phase II Consortium study

6 September 2017

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Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth

6 September 2017

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Integration of novel therapeutics into combined modality therapy of locally advanced non-small cell lung cancer

6 September 2017

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The DNA damage response: sensing and signaling

6 September 2017

1 reference

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Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

6 September 2017

1 reference

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ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses.

6 September 2017

1 reference

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Chk1 and Chk2 kinases in checkpoint control and cancer

6 September 2017

1 reference

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ATR Regulates Fragile Site Stability

6 September 2017

1 reference

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

6 September 2017

1 reference

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

6 September 2017

1 reference

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Monoclonal antibodies to mitotic cells

6 September 2017

1 reference

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Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity

6 September 2017

1 reference

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2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity

14 September 2017

1 reference

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Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

14 September 2017

1 reference

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Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase

14 September 2017

1 reference

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Involvement of the Fhit gene in the ionizing radiation-activated ATR/CHK1 pathway

14 September 2017

1 reference

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Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.

14 September 2017

1 reference

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The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe

14 September 2017

1 reference

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Histone Phosphorylation and Chromatin Structure during Mitosis in Chinese Hamster Cells

14 September 2017

1 reference

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The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells

14 September 2017

1 reference

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R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.

26 June 2018

1 reference

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DNA damage-mediated apoptosis induced by selenium compounds.

2 September 2018

1 reference

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Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation

2 September 2018

1 reference

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ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase

2 September 2018

1 reference

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UCN-01 enhances the in vitro toxicity of clinical agents in human tumor cell lines

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19881958

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA double-strand breaks measured in individual cells subjected to gel electrophoresis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19881958

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Paradoxical relationship between acetylator phenotype and amonafide toxicity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19881958

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1593/NEO.09986

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19881958%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19881958%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference