Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma. (Q37391981)

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scientific article published on 11 August 2016

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English	Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma.	scientific article published on 11 August 2016

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23 March 2020

Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma (English)

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Manlio Vinciguerra

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Francesc Villarroya

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Valerio Pazienza

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Francesco Cappello

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Simone Jueliger

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John Lyons

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Sara Cannito

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Illar Pata

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Pille Pata

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Marianna Shkolnaya

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Oriana Lo Re

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Francesca Rappa

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Mohammad Azab

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Pietro Taverna

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20 September 2016

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709-720

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20 September 2016

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DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression

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Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study

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Guadecitabine (SGI-110) priming sensitizes hepatocellular carcinoma cells to oxaliplatin

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Immunomodulatory action of SGI-110, a hypomethylating agent, in acute myeloid leukemia cells and xenografts.

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SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome

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SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation

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10.1080/15592294.2016.1214781

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23 March 2020

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