DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression (Q36672313)

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scientific article published on 15 January 2016

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English	DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression	scientific article published on 15 January 2016

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scholarly article

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Europe PubMed Central

15 August 2017

DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression (English)

1 reference

Europe PubMed Central

15 August 2017

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

Caterina Fusilli

2

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11 June 2020

Concetta Panebianco

4

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Gianluigi Mazzoccoli

7

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11 June 2020

Chris G. Faulkes

8

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11 June 2020

Marcus Buschbeck

17

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11 June 2020

Francesco Cappello

18

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11 June 2020

Valerio Pazienza

20

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11 June 2020

Manlio Vinciguerra

21

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11 June 2020

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Michela Borghesan

1

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11 June 2020

Francesca Rappa

3

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11 June 2020

Giovanni Rizzo

5

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11 June 2020

Jude A Oben

6

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11 June 2020

Illar Pata

9

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11 June 2020

Antonella Agodi

10

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11 June 2020

Farhad Rezaee

11

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11 June 2020

Shane Minogue

12

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11 June 2020

Alessandra Warren

13

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11 June 2020

Abigail Peterson

14

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11 June 2020

John M Sedivy

15

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11 June 2020

Julien Douet

16

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11 June 2020

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publication date

15 January 2016

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15 August 2017

Cancer Research

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11 June 2020

76

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11 June 2020

3

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11 June 2020

594-606

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11 June 2020

MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype

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30 September 2017

Fasting cycles potentiate the efficacy of gemcitabine treatment in in vitro and in vivo pancreatic cancer models.

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Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase

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MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis

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Obesity accelerates epigenetic aging of human liver

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Decade in review-hepatocellular carcinoma: HCC-subtypes, stratification and sorafenib

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Histone variants and lipid metabolism

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Genetic ablation of macrohistone H2A1 leads to increased leanness, glucose tolerance and energy expenditure in mice fed a high-fat diet

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IL-17A produced by γδ T cells promotes tumor growth in hepatocellular carcinoma.

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SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation

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macroH2A1 histone variant represses rDNA transcription

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Differential induction of apoptosis and senescence by the DNA methyltransferase inhibitors 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumor cells

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Liver diseases and aging: friends or foes?

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30 September 2017

Mutual antagonism between circadian protein period 2 and hepatitis C virus replication in hepatocytes

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MacroH2A--an epigenetic regulator of cancer

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Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

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Immunopositivity for histone macroH2A1 isoforms marks steatosis-associated hepatocellular carcinoma

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MacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells

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30 September 2017

QKI-mediated alternative splicing of the histone variant MacroH2A1 regulates cancer cell proliferation

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Hypermethylated levels of E-cadherin promoter in Huh-7 cells expressing the HCV core protein

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30 September 2017

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

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30 September 2017

Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A).

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30 September 2017

Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin

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30 September 2017

Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists

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Histone variant macroH2A1 deletion in mice causes female-specific steatosis

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The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

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30 September 2017

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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Using LUMA: a Luminometric-based assay for global DNA-methylation

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Identifiers

10.1158/0008-5472.CAN-15-1336

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11 June 2020

1 reference

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11 June 2020

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11 June 2020

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