Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS. (Q37381821)

20 August 2017

Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS. (English)

1 reference

amyotrophic lateral sclerosis

20 August 2017

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1 reference

Mohammad Shahidullah

1

1 reference

20 August 2017

Sylvain J Le Marchand

2

1 reference

20 August 2017

Hong Fei

3

1 reference

20 August 2017

Jiaming Zhang

4

1 reference

20 August 2017

Udai Bhan Pandey

5

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20 August 2017

Matthew B Dalva

6

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20 August 2017

Piera Pasinelli

7

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20 August 2017

Irwin B Levitan

8

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20 August 2017

language of work or name

English

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publication date

1 December 2013

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20 August 2017

Journal of Neuroscience

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20 August 2017

33

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20 August 2017

50

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20 August 2017

19590-19598

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describes a project that uses

20 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3858628/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.

1 reference

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Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability

6 September 2017

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Knockdown of the Drosophila fused in sarcoma (FUS) homologue causes deficient locomotive behavior and shortening of motoneuron terminal branches.

6 September 2017

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Misregulated RNA processing in amyotrophic lateral sclerosis

6 September 2017

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Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS

6 September 2017

1 reference

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6 September 2017

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The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.

6 September 2017

1 reference

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A Drosophila model of FUS-related neurodegeneration reveals genetic interaction between FUS and TDP-43.

6 September 2017

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FUS transgenic rats develop the phenotypes of amyotrophic lateral sclerosis and frontotemporal lobar degeneration

6 September 2017

1 reference

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Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models

6 September 2017

1 reference

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Rethinking ALS: the FUS about TDP-43.

6 September 2017

1 reference

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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

6 September 2017

1 reference

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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

6 September 2017

1 reference

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Neonatal neuronal circuitry shows hyperexcitable disturbance in a mouse model of the adult-onset neurodegenerative disease amyotrophic lateral sclerosis

6 September 2017

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

6 September 2017

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

6 September 2017

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RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release

6 September 2017

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Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

14 September 2017

1 reference

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Distinct frequency-dependent regulation of nerve terminal excitability and synaptic transmission by IA and IK potassium channels revealed by Drosophila Shaker and Shab mutations.

14 September 2017

1 reference

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Calcium channel agonists protect against neuromuscular dysfunction in a genetic model of TDP-43 mutation in ALS.

26 June 2018

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Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila

2 September 2018

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2 September 2018

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Bruchpilot promotes active zone assembly, Ca2+ channel clustering, and vesicle release

2 September 2018

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A modified minimal hemolymph-like solution, HL3.1, for physiological recordings at the neuromuscular junctions of normal and mutant Drosophila larvae

2 September 2018

1 reference

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Regional distribution of proteinase K-resistant alpha-synuclein correlates with Lewy body disease stage.

2 September 2018

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Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice.

2 September 2018

1 reference

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Even-skipped, acting as a repressor, regulates axonal projections in Drosophila.

2 September 2018

1 reference

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Development of the embryonic neuromuscular synapse of Drosophila melanogaster.

2 September 2018

1 reference

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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24336723

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.3396-13.2013

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

24336723

1 reference