Costimulation as a platform for the development of vaccines: a peptide-based vaccine containing a novel form of 4-1BB ligand eradicates established tumors (Q37370587)

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scientific article published on 12 May 2009

Language	Label	Description	Also known as
English	Costimulation as a platform for the development of vaccines: a peptide-based vaccine containing a novel form of 4-1BB ligand eradicates established tumors	scientific article published on 12 May 2009

Statements

scholarly article

1 reference

Europe PubMed Central

20 August 2017

Costimulation as a platform for the development of vaccines: a peptide-based vaccine containing a novel form of 4-1BB ligand eradicates established tumors (English)

1 reference

Europe PubMed Central

20 August 2017

eradication of infectious diseases

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Rajesh K Sharma

1

1 reference

Europe PubMed Central

20 August 2017

Kutlu G Elpek

2

1 reference

Europe PubMed Central

20 August 2017

Esma S Yolcu

3

1 reference

Europe PubMed Central

20 August 2017

Rich-Henry Schabowsky

4

1 reference

Europe PubMed Central

20 August 2017

Hong Zhao

5

1 reference

Europe PubMed Central

20 August 2017

Laura Bandura-Morgan

6

1 reference

Europe PubMed Central

20 August 2017

Haval Shirwan

7

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

12 May 2009

1 reference

Europe PubMed Central

20 August 2017

Cancer Research

1 reference

Europe PubMed Central

20 August 2017

69

1 reference

Europe PubMed Central

20 August 2017

10

1 reference

Europe PubMed Central

20 August 2017

4319-4326

1 reference

Europe PubMed Central

20 August 2017

CD137 costimulation of CD8+ T cells confers resistance to suppression by virus-induced regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Toll or toll-free adjuvant path toward the optimal vaccine development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Cooperation of Toll-like receptor signals in innate immune defence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

RETRACTED: B7-DC cross-linking restores antigen uptake and augments antigen-presenting cell function by matured dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Interfacing T-cell effector and regulatory function through CD137 (4-1BB) co-stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

TNF/TNFR family members in costimulation of T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Cancer vaccines: between the idea and the reality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Cutting edge: Expression of functional CD137 receptor by dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

6 September 2017

CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

14 September 2017

Eradication of established tumors in mice by a combination antibody-based therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

14 September 2017

Generation of a multimeric form of CD40L with potent immunostimulatory activity using streptavidin as a chaperon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

14 September 2017

Turning on/off tumor-specific CTL response during progressive tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

14 September 2017

Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

26 June 2018

Combined CD137 (4-1BB) and adjuvant therapy generates a developing pool of peptide-specific CD8 memory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

26 June 2018

In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

26 June 2018

Differential costimulation through CD137 (4-1BB) restores proliferation of human virus-specific "effector memory" (CD28(-) CD45RA(HI)) CD8(+) T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

2 September 2018

Combination of tumor site-located CTL-associated antigen-4 blockade and systemic regulatory T-cell depletion induces tumor-destructive immune responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

2 September 2018

Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

2 September 2018

TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

2 September 2018

Cell membrane modification for rapid display of proteins as a novel means of immunomodulation: FasL-decorated cells prevent islet graft rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

2 September 2018

Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

2 September 2018

Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755220

2 September 2018

The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Dendritic Cells That Cross-Present Tumor-Derived Antigen Licenses CD8+ CTL to Cause Tumor Eradication

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance to rat heart grafts induced by intrathymic immunomodulation is mediated by indirect recognition primed CD4+CD25+ Treg cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The low-toxicity versions of LPS, MPL adjuvant and RC529, are efficient adjuvants for CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eradication of large tumors in mice by a tritherapy targeting the innate, adaptive, and regulatory components of the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ex vivo expansion of CD4+CD25+FoxP3+ T regulatory cells based on synergy between IL-2 and 4-1BB signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: cancer and leukemia group B study 89903

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19435920

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-3141

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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