Defects in Jak-STAT-mediated cytokine signals cause hyper-IgE syndrome: lessons from a primary immunodeficiency (Q37352441)

19 August 2017

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title

Defects in Jak-STAT-mediated cytokine signals cause hyper-IgE syndrome: lessons from a primary immunodeficiency (English)

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19 August 2017

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Yoshiyuki Minegishi

1

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PubMed ID

19088064

19 August 2017

Hajime Karasuyama

series ordinal

2

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PubMed ID

19088064

19 August 2017

language of work or name

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15 December 2008

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19 August 2017

International Immunology

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19 August 2017

21

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19 August 2017

2

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19 August 2017

105-112

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Defects in early B-cell development: comparing the consequences of abnormalities in pre-BCR signaling in the human and the mouse

19 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Mutations in the mu heavy-chain gene in patients with agammaglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Mutations in the human lambda5/14.1 gene result in B cell deficiency and agammaglobulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

An essential role for BLNK in human B cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Mutations in Igalpha (CD79a) result in a complete block in B-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Job's Syndrome. Recurrent, "cold", staphylococcal abscesses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Hyper-IgE syndrome with recurrent infections--an autosomal dominant multisystem disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Autosomal recessive hyperimmunoglobulin E syndrome: a distinct disease entity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Hyperimmunoglobulin E syndrome and tyrosine kinase 2 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

No indication for a defect in toll-like receptor signaling in patients with hyper-IgE syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Causes of death in hyper-IgE syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Genetic linkage of hyper-IgE syndrome to chromosome 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Defect in neutrophil granulocyte chemotaxis in Job's syndrome of recurrent "cold" staphylococcal abscesses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Defective in vitro production of gamma-interferon and tumor necrosis factor-alpha by circulating T cells from patients with the hyper-immunoglobulin E syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Defective interleukin-12/interferon-gamma pathway in patients with hyperimmunoglobulinemia E syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Cytokine and chemokine dysregulation in hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Inherited defects in the interferon-gamma receptor or interleukin-12 signalling pathways are not sufficient to cause allergic disease in children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Cytokine receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

JAK/STAT signaling by cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Genetic dissection of immunity to mycobacteria: the human model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Partial impairment of cytokine responses in Tyk2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

STAT3Mutation in the Original Patient with Job's Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

STAT3 mutations in the hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Signal transducer and activator of transcription 3 is the dominant mediator of the anti-inflammatory effects of IL-10 in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Roles of STAT3 defined by tissue-specific gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Cutting edge: interleukin 17 signals through a heteromeric receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

IL-22 increases the innate immunity of tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN134

21 January 2018

Identifiers

DOI

10.1093/INTIMM/DXN134

1 reference

19 August 2017

1 reference

PubMed ID

19088064