PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1. (Q37331013)

19 August 2017

PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1. (English)

1 reference

19 August 2017

Saijilafu

1

1 reference

19 August 2017

Eun-Mi Hur

2

1 reference

19 August 2017

Chang-Mei Liu

3

1 reference

19 August 2017

Zhongxian Jiao

4

1 reference

19 August 2017

Wen-Lin Xu

5

1 reference

19 August 2017

Feng-Quan Zhou

6

1 reference

19 August 2017

language of work or name

English

0 references

publication date

1 January 2013

1 reference

19 August 2017

Nature Communications

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19 August 2017

4

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19 August 2017

2690

1 reference

https://scigraph.springernature.com/pub.10.1038/ncomms3690

19 August 2017

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cites work

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c-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling.

6 September 2017

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Coordinating Gene Expression and Axon Assembly to Control Axon Growth: Potential Role of GSK3 Signaling

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Assembly of a new growth cone after axotomy: the precursor to axon regeneration

6 September 2017

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Growing the growth cone: remodeling the cytoskeleton to promote axon regeneration

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GSK-3: Functional Insights from Cell Biology and Animal Models

6 September 2017

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Genetic dissection of axon regeneration via in vivo electroporation of adult mouse sensory neurons

6 September 2017

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GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules

6 September 2017

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A Smad action turnover switch operated by WW domain readers of a phosphoserine code

6 September 2017

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Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways

6 September 2017

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Regeneration of axons in injured spinal cord by activation of bone morphogenetic protein/Smad1 signaling pathway in adult neurons.

6 September 2017

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Neuronal intrinsic mechanisms of axon regeneration.

6 September 2017

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Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules.

6 September 2017

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Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injury

6 September 2017

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Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

6 September 2017

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Genetic dissection of axon regeneration

6 September 2017

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PTEN deletion enhances the regenerative ability of adult corticospinal neurons

6 September 2017

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GSK3 signalling in neural development

6 September 2017

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Mammalian target of rapamycin (mTOR) activation increases axonal growth capacity of injured peripheral nerves

6 September 2017

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PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons.

6 September 2017

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The neurodevelopmental implications of PI3K signaling

6 September 2017

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The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration

6 September 2017

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Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling

6 September 2017

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Axon regeneration requires a conserved MAP kinase pathway.

6 September 2017

1 reference

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Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

6 September 2017

1 reference

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Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

6 September 2017

1 reference

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Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Defining the role of mTOR in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Recapitulate development to promote axonal regeneration: good or bad approach?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Smad transcription factors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Regeneration beyond the glial scar

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Axonal regeneration in the rat sciatic nerve: Effect of a conditioning lesion and of dbcAMP

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Compartmentalized microfluidic culture platform to study mechanism of paclitaxel-induced axonal degeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Degeneration and regeneration of axons in the lesioned spinal cord

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

A transcription-dependent switch controls competence of adult neurons for distinct modes of axon growth.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Axon Outgrowth Enhanced by a Previous Nerve Injury

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Axotomy-induced Smad1 activation promotes axonal growth in adult sensory neurons.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Inactivation of glycogen synthase kinase 3 promotes axonal growth and recovery in the CNS.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Cell biology. GSK-3beta and microtubule assembly in axons.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Raf and akt mediate distinct aspects of sensory axon growth

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3836055

Activated CREB is sufficient to overcome inhibitors in myelin and promote spinal axon regeneration in vivo

2 September 2018

1 reference

12 December 2020

Neurotrophins support regenerative axon assembly over CSPGs by an ECM-integrin-independent mechanism

1 reference

12 December 2020

c-Jun expression in adult rat dorsal root ganglion neurons: differential response after central or peripheral axotomy

1 reference

12 December 2020

Cellular responses to axotomy and to related procedures

1 reference

12 December 2020

Time course of the conditioning lesion effect on axonal regeneration

1 reference

12 December 2020

Increased regeneration rate in peripheral nerve axons following double lesions: enhancement of the conditioning lesion phenomenon

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS3690

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Dimensions Publication ID

19 August 2017

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19 August 2017

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