Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers. (Q37259269)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24135138%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers (English)

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28 February 2020

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Cristina Montero-Conde

4

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28 February 2020

Jeffrey A Knauf

6

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28 February 2020

Tetiana Bogdanova

9

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28 February 2020

11

Christopher E Mason

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28 February 2020

author name string

Julio C Ricarte-Filho

1

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28 February 2020

Sheng Li

2

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28 February 2020

Maria E R Garcia-Rendueles

3

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28 February 2020

Francesca Voza

5

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28 February 2020

Adriana Heguy

7

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28 February 2020

Agnes Viale

8

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28 February 2020

Geraldine A Thomas

10

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28 February 2020

James A Fagin

12

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28 February 2020

language of work or name

English

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publication date

25 October 2013

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Journal of Clinical Investigation

28 February 2020

published in

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28 February 2020

volume

123

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28 February 2020

issue

11

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28 February 2020

page(s)

4935-4944

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The cellular etiology of chromosome translocations.

28 February 2020

cites work

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Molecular genetics and diagnosis of thyroid cancer

6 September 2017

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A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines

6 September 2017

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6 September 2017

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Mutational profile of advanced primary and metastatic radioactive iodine-refractory thyroid cancers reveals distinct pathogenetic roles for BRAF, PIK3CA, and AKT1.

6 September 2017

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(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

6 September 2017

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ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages

6 September 2017

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Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer

6 September 2017

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NCBI GEO: mining millions of expression profiles--database and tools

6 September 2017

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Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

6 September 2017

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ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation

6 September 2017

1 reference

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Cancer after nuclear fallout: lessons from the Chernobyl accident

6 September 2017

1 reference

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Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications

6 September 2017

1 reference

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Gene rearrangement and Chernobyl related thyroid cancers

6 September 2017

1 reference

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A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

6 September 2017

1 reference

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Prevalence of mutations in TSHR, GNAS, PRKAR1A and RAS genes in a large series of toxic thyroid adenomas from Galicia, an iodine-deficient area in NW Spain.

6 September 2017

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Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident

26 June 2018

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CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis.

26 June 2018

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Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.

3 September 2018

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The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.

3 September 2018

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PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.

3 September 2018

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Preferential induction of RET/PTC1 rearrangement by X-ray irradiation

3 September 2018

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12 December 2020

Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells

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12 December 2020

High prevalence of RET rearrangement in thyroid tumors of children from Belarus after the Chernobyl reactor accident

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12 December 2020

Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.

1 reference

12 December 2020

High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation

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12 December 2020

Proximity ofTPRandNTRK1Rearranging Loci in Human Thyrocytes

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12 December 2020

Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: a model of carcinogenic chromosomal rearrangement induced by ionizing radiation

1 reference

12 December 2020

Risk of thyroid cancer after exposure to 131I in childhood

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12 December 2020

Oncogenic alterations in papillary thyroid cancers of young patients

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12 December 2020

ETV6 rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events

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12 December 2020

Identifiers

DOI

10.1172/JCI69766

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24135138%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24135138%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference