Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer (Q27824825)

6

object named as

Marina N Nikiforova

0 references

Jeffrey A Knauf

object named as

Jeffrey A Knauf

2

1 reference

ORCID Public Data File 2021

author name string

Raffaele Ciampi

1

0 references

Roswitha Kerler

3

0 references

Manoj Gandhi

4

0 references

Zhaowen Zhu

5

0 references

Hartmut M Rabes

7

0 references

James A Fagin

Journal of Clinical Investigation

8

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language of work or name

English

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publication date

January 2005

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published in

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volume

115

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page(s)

94-101

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issue

1

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cites work

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Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

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AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes

20 March 2017

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Activation of a novel human transforming gene, ret, by DNA rearrangement

20 March 2017

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Induction of centrosome amplification and chromosome instability in human bladder cancer cells by p53 mutation and cyclin E overexpression

20 March 2017

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29 September 2017

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Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications

29 September 2017

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A-kinase anchoring proteins: protein kinase A and beyond

29 September 2017

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29 September 2017

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29 September 2017

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Structure and expression of the ret transforming gene

29 September 2017

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B-raf, a new member of the raf family, is activated by DNA rearrangement

29 September 2017

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PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

29 September 2017

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Development of a highly efficient expression cDNA cloning system: application to oncogene isolation

29 September 2017

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Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.

29 September 2017

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NTRK1 re-arrangement in papillary thyroid carcinomas of children after the Chernobyl reactor accident

29 September 2017

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2 June 2018

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A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins

2 June 2018

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Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident

2 June 2018

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A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases

2 June 2018

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Chromosomal assignment of two human B-raf(Rmil) proto-oncogene loci: B-raf-1 encoding the p94Braf/Rmil and B-raf-2, a processed pseudogene.

2 June 2018

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High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines.

2 June 2018

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Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations.

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539203

RET/PTC-induced dedifferentiation of thyroid cells is mediated through Y1062 signaling through SHC-RAS-MAP kinase

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539203

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539203

RAF/RAS oncogenes and mismatch-repair status

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539203

RET expression in papillary thyroid cancer from patients irradiated in childhood for benign conditions.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539203

Chromosome 1 rearrangements involving the genes TPR and NTRK1 produce structurally different thyroid-specific TRK oncogenes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539203

Distinct frequency of ret rearrangements in papillary thyroid carcinomas of children and adults from Belarus

27 November 2018

1 reference

12 December 2020

Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells

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12 December 2020

Cancer. Proximity matters

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12 December 2020

BRAF and RAS mutations in human lung cancer and melanoma

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12 December 2020

BRAF Mutation in Papillary Thyroid Carcinoma

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12 December 2020

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

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12 December 2020

Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer.

1 reference

12 December 2020

High prevalence of RET rearrangement in thyroid tumors of children from Belarus after the Chernobyl reactor accident

1 reference

12 December 2020

Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.

1 reference

12 December 2020

High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation

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12 December 2020