Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta. (Q37257169)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19541930%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19541930%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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3

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31 January 2020

author name string

Jennifer C Palmer

series ordinal

1

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31 January 2020

Shabnam Baig

series ordinal

2

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31 January 2020

Seth Love

series ordinal

4

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31 January 2020

language of work or name

English

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publication date

18 June 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19541930%20AND%20SRC:MED&resulttype=core&format=json

The American Journal of Pathology

31 January 2020

published in

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31 January 2020

volume

175

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31 January 2020

page(s)

262-270

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31 January 2020

issue

1

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Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory

31 January 2020

cites work

1 reference

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6 September 2017

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ApoE promotes the proteolytic degradation of Abeta

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides

6 September 2017

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Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele

6 September 2017

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

6 September 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 September 2017

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A beta-peptides enhance vasoconstriction in cerebral circulation

6 September 2017

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beta-Amyloid efflux mediated by p-glycoprotein

6 September 2017

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Exogenous A beta1-40 reproduces cerebrovascular alterations resulting from amyloid precursor protein overexpression in mice

6 September 2017

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Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

6 September 2017

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Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development

6 September 2017

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Tc-99m HMPAO SPECT in the evaluation of Alzheimer's disease: correlation between neuropsychiatric evaluation and CBF images

6 September 2017

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Cerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease

6 September 2017

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Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum

6 September 2017

1 reference

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Neuropathological stageing of Alzheimer-related changes

6 September 2017

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New developments in the understanding of cerebral vasoregulation and vasospasm: the endothelin-nitric oxide network.

6 September 2017

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Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

14 September 2017

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Hydrolysis of peptide hormones by endothelin-converting enzyme-1. A comparison with neprilysin

28 September 2017

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Activated isoforms of MMP-2 are induced in U87 human glioma cells in response to beta-amyloid peptide

28 September 2017

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Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy.

28 September 2017

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Alterations in cerebral blood flow and glucose utilization in mice overexpressing the amyloid precursor protein

26 June 2018

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Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition

26 June 2018

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Cerebral vessels in ageing and Alzheimer's disease

26 June 2018

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Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin

26 June 2018

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Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats.

26 June 2018

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Assessing utility of single photon emission computed tomography (SPECT) scan in Alzheimer disease: correlation with cognitive severity

26 June 2018

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Characterisation of two antibodies to oligomeric Abeta and their use in ELISAs on human brain tissue homogenates.

26 June 2018

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Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.

3 September 2018

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Age-dependent decline of neprilysin in Alzheimer's disease and normal brain: inverse correlation with A beta levels.

3 September 2018

1 reference

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Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology.

3 September 2018

1 reference

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Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708812

Neprylisin decreases uniformly in Alzheimer's disease and in normal aging.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708812

Decreased neprilysin immunoreactivity in Alzheimer disease, but not in pathological aging.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708812

The relationship between cerebral blood flow and cognitive function in patients with brain insult of various etiology.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708812

Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708812

Pathogenic A beta induces the expression and activation of matrix metalloproteinase-2 in human cerebrovascular smooth muscle cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708812

Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid beta from the human brain

3 September 2018

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3 September 2018

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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708812

Declining expression of neprilysin in Alzheimer disease vasculature: possible involvement in cerebral amyloid angiopathy

3 September 2018

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Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein

3 September 2018

1 reference

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Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide.

3 September 2018

1 reference

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Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.

3 September 2018

1 reference

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beta-Amyloid-mediated vasoactivity and vascular endothelial damage.

3 September 2018

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Contribution of endogenous generation of endothelin-1 to basal vascular tone

3 September 2018

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12 December 2020

Tissue plasminogen activator requires plasminogen to modulate amyloid-beta neurotoxicity and deposition

1 reference

12 December 2020

Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in humans

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12 December 2020

Cellular Expression of Isoforms of Endothelin-Converting Enzyme-1 (ECE-1c, ECE-1b and ECE-1a) and Endothelin-Converting Enzyme-2

1 reference

12 December 2020

Endothelins in health and disease

1 reference

12 December 2020

Neuroimaging in dementia

1 reference

12 December 2020

Characteristics of the in vitro vasoactivity of beta-amyloid peptides

1 reference

12 December 2020

10.2353/AJPATH.2009.081054

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19541930%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19541930%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference