SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis (Q37243181)

19 August 2017

SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis (English)

1 reference

19 August 2017

Dawn E Watkins-Chow

2

0 references

Stacie K Loftus

Stacie K Loftus

10

0 references

William J Pavan

William J Pavan

11

0 references

Boris C. Bastian

Boris C Bastian

8

0 references

Art Incao

3

Art Incao

1 reference

19 August 2017

9

Reinhard Dummer

1 reference

19 August 2017

Julia C Cronin

1

1 reference

19 August 2017

Joanne H Hasskamp

4

1 reference

19 August 2017

Nicola Schönewolf

5

1 reference

19 August 2017

Lauren G Aoude

6

1 reference

19 August 2017

Nicholas K Hayward

7

1 reference

19 August 2017

language of work or name

English

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publication date

1 August 2013

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19 August 2017

10

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inferred from page(s)

published in

Cancer Research

1 reference

19 August 2017

73

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19 August 2017

18

1 reference

19 August 2017

5709-5718

1 reference

describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3803156/fullTextXML

inferred from PubMed Central ID database lookup

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The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

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A landscape of driver mutations in melanoma

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Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

6 September 2017

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Melanoma genome sequencing reveals frequent PREX2 mutations

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Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

6 September 2017

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Identification and functional analysis of SOX10 missense mutations in different subtypes of Waardenburg syndrome

6 September 2017

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The melanomas: a synthesis of epidemiological, clinical, histopathological, genetic, and biological aspects, supporting distinct subtypes, causal pathways, and cells of origin

6 September 2017

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PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein

6 September 2017

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Exome sequencing identifies GRIN2A as frequently mutated in melanoma

6 September 2017

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PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

6 September 2017

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Genetic and morphologic features for melanoma classification

6 September 2017

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Frequent mutations in the MITF pathway in melanoma

6 September 2017

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A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy

6 September 2017

1 reference

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Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

6 September 2017

1 reference

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Genome-scale loss-of-function screening with a lentiviral RNAi library

6 September 2017

1 reference

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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

6 September 2017

1 reference

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Rb/E2F: a two-edged sword in the melanocytic system

6 September 2017

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Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

6 September 2017

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MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A

6 September 2017

1 reference

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Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF

6 September 2017

1 reference

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

6 September 2017

1 reference

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Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3

6 September 2017

1 reference

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Phenotypic heterogeneity of melanoma. Relation to the differentiation program of melanoma cells

6 September 2017

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Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.

6 September 2017

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SOX10 expression in superficial spreading and nodular malignant melanomas

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

MiTF links Erk1/2 kinase and p21 CIP1/WAF1 activation after UVC radiation in normal human melanocytes and melanoma cells

14 September 2017

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Microphthalmia-associated transcription factor controls the DNA damage response and a lineage-specific senescence program in melanomas.

14 September 2017

1 reference

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SOX9 and SOX10 but not BRN2 are required for nestin expression in human melanoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

The transcription factor Sox10 is a key regulator of peripheral glial development.

14 September 2017

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The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

14 September 2017

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E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

BRAF inhibitors for the treatment of metastatic melanoma: clinical trials and mechanisms of resistance

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

Retinoic acid-mediated induction of neurons and glial cells from human umbilical cord-derived hematopoietic stem cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

Nestin and SOX9 and SOX10 transcription factors are coexpressed in melanoma

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3803156

Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23913827

12 December 2020

inferred from PubMed ID database lookup

Sox10: a pan-schwannian and melanocytic marker

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23913827

12 December 2020

inferred from PubMed ID database lookup

Mitf dosage as a primary determinant of melanocyte survival after ultraviolet irradiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23913827

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1158/0008-5472.CAN-12-4620

1 reference

19 August 2017

1 reference

19 August 2017

1 reference