Transforming growth factor-beta in breast cancer: too much, too late (Q37205559)

18 August 2017

3 references

3 April 2019

20 November 2019

8 February 2021

Transforming growth factor-beta in breast cancer: too much, too late (English)

1 reference

18 August 2017

1 reference

3 April 2019

1 reference

20 November 2019

1 reference

8 February 2021

1 reference

2

Rosemary J Akhurst

1 reference

18 August 2017

Mary Helen Barcellos-Hoff

series ordinal

1

1 reference

18 August 2017

26 February 2009

4 references

18 August 2017

3 April 2019

20 November 2019

8 February 2021

Breast Cancer Research

4 references

18 August 2017

3 April 2019

20 November 2019

8 February 2021

11

1 reference

18 August 2017

1

1 reference

18 August 2017

202

1 reference

https://scigraph.springernature.com/pub.10.1186/bcr2224

18 August 2017

0 references

cites work

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An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

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TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

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6 September 2017

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Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.

6 September 2017

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Molecular definition of breast tumor heterogeneity

6 September 2017

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TGF beta inhibition for cancer therapy

6 September 2017

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Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility.

6 September 2017

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Paradoxical roles of the immune system during cancer development

6 September 2017

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Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials

6 September 2017

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Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

6 September 2017

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Initiating cellular stress responses

6 September 2017

1 reference

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Reconstruction of functionally normal and malignant human breast tissues in mice

6 September 2017

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Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression

6 September 2017

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

6 September 2017

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Epithelial-mesenchymal transition and its implications for fibrosis

6 September 2017

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Epithelial-mesenchymal transitions in development and pathologies

6 September 2017

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Cell adhesion system and human cancer morphogenesis

6 September 2017

1 reference

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Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

6 September 2017

1 reference

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ATM: sounding the double-strand break alarm

6 September 2017

1 reference

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The not-so innocent bystander: the microenvironment as a therapeutic target in cancer

6 September 2017

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Epithelial-mesenchymal transitions in tumour progression

6 September 2017

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Stromal effects on mammary gland development and breast cancer

6 September 2017

1 reference

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Putting tumours in context

6 September 2017

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Malignant cells, directors of the malignant process: role of transforming growth factor-beta

6 September 2017

1 reference

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TGF-beta signaling in tumor suppression and cancer progression

6 September 2017

1 reference

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Association between the T29-->C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The Study of Osteoporotic Fractures.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

The potential influence of radiation-induced microenvironments in neoplastic progression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

TGF-beta1 and radiation fibrosis: a master switch and a specific therapeutic target?

6 September 2017

1 reference

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Reversible inhibition of mammary gland growth by transforming growth factor-beta

6 September 2017

1 reference

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

17-Beta-estradiol inhibits transforming growth factor-beta signaling and function in breast cancer cells via activation of extracellular signal-regulated kinase through the G protein-coupled receptor 30.

6 September 2017

1 reference

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Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

TGFbeta-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFbeta-receptor I signalling.

14 September 2017

1 reference

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A novel functional polymorphism in the transforming growth factor-beta2 gene promoter and tumor progression in breast cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Association of cytokine gene polymorphisms with malignant melanoma in Caucasian population

14 September 2017

1 reference

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Cancer as a dynamic developmental disorder

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Transforming growth factor-beta and response to anticancer therapies in human liver and gastric tumors in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Transforming growth factor-beta 1 overexpression produces drug resistance in vivo: reversal by decorin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Response of normal and oncogene-transformed human mammary epithelial cells to transforming growth factor beta 1 (TGF-beta 1): lack of growth-inhibitory effect on cells expressing the simian virus 40 large-T antigen

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Polymorphisms in TGF-beta1 gene and the risk of lung cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Genetic polymorphisms of the transforming growth factor-beta1 gene and breast cancer risk: a possible dual role at different cancer stages

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer risk

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

A gain of function TGFB1 polymorphism may be associated with late stage prostate cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

The stroma as a crucial target in rat mammary gland carcinogenesis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Transforming growth factor-beta1 mediates cellular response to DNA damage in situ.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Increased TGFbeta1 plasma level in patients with lung cancer: potential mechanisms

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Somatic mutation theory of carcinogenesis: why it should be dropped and replaced.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Transforming growth factor B1 T29C polymorphism and breast cancer risk in Japanese women

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FBCR2224

A common coding variant in CASP8 is associated with breast cancer risk

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2687712

Elevated plasma transforming growth factor-beta 1 levels in breast cancer patients decrease after surgical removal of the tumor

4 December 2018

1 reference

12 December 2020

Transforming growth factor-beta in in vivo resistance

1 reference

12 December 2020

Polymorphisms of the transforming growth factor-beta 1 gene in relation to myocardial infarction and blood pressure. The Etude Cas-Témoin de l'Infarctus du Myocarde (ECTIM) Study

1 reference

12 December 2020

Reversal of in vivo drug resistance by the transforming growth factor-beta inhibitor decorin

1 reference

12 December 2020

Dynamics of tumor oxygenation, CD31 staining and transforming growth factor-beta levels after treatment with radiation or cyclophosphamide in the rat 13762 mammary carcinoma

1 reference

12 December 2020

Blockade of tumor cell transforming growth factor-betas enhances cell cycle progression and sensitizes human breast carcinoma cells to cytotoxic chemotherapy

1 reference

12 December 2020

TbetaR-I(6A) is a candidate tumor susceptibility allele

1 reference

12 December 2020

Circulating transforming growth factor beta 1 as a predictor of liver metastasis after resection in colorectal cancer

1 reference

12 December 2020

Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice

1 reference

12 December 2020

Antitransforming growth factor-beta antibody 1D11 ameliorates normal tissue damage caused by high-dose radiation

1 reference

12 December 2020

Association of transforming growth factor-beta1 gene polymorphisms with genetic susceptibility to nasopharyngeal carcinoma

1 reference

12 December 2020

Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF- b1 haploinsufficiency

1 reference

12 December 2020

TGF beta signaling in health and disease

1 reference

12 December 2020

Transforming growth factor beta as a predictor of liver and lung fibrosis after autologous bone marrow transplantation for advanced breast cancer

1 reference

12 December 2020

Identifiers

DOI

10.1186/BCR2224

1 reference

PMCID

2687712

Dimensions Publication ID

18 August 2017

0 references

1 reference

18 August 2017

1 reference

PMCID

2687712