TGF-beta1 and radiation fibrosis: a master switch and a specific therapeutic target? (Q33913350)

30 July 2017

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title

TGF-beta1 and radiation fibrosis: a master switch and a specific therapeutic target? (English)

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30 July 2017

Martin M

1

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30 July 2017

Lefaix J

series ordinal

2

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30 July 2017

Delanian S

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 May 2000

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International Journal of Radiation Oncology Biology Physics

30 July 2017

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30 July 2017

47

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30 July 2017

277-290

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30 July 2017

2

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The transforming growth factor-beta family

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Beta-transforming growth factor is stored in human blood platelets as a latent high molecular weight complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Latent transforming growth factor-beta binding proteins (LTBPs)--structural extracellular matrix proteins for targeting TGF-beta action

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

TGF-beta: receptors and cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

SMADs: mediators and regulators of TGF-beta signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

The importance of context in cytokine action

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Coordinated regulation of apoptosis and cell proliferation by transforming growth factor beta 1 in cultured uterine epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

1,25-dihydroxyvitamin D3, transforming growth factor beta1, calcium, and ultraviolet B radiation induce apoptosis in cultured human keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Expression of a dominant negative type II TGF-beta receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Mutations of the transforming growth factor-beta type II receptor gene are strongly related to sporadic proximal colon carcinomas with microsatellite instability.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Differential regulation of p27 and cyclin D1 by TGF-beta and EGF in C3H 10T1/2 mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Pathology of recombinant human transforming growth factor-beta 1 in rats and rabbits.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Latent-time estimation for late cutaneous and subcutaneous radiation reactions in a single-follow-up clinical study

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Diagnosis of acute localized irradiation lesions: review of the French experimental experience

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Injury to the lung from cancer therapy: clinical syndromes, measurable endpoints, and potential scoring systems

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Radiation hepatology of the rat: parenchymal and nonparenchymal cell injury

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Cellular basis of radiation-induced fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Changes in histology and fibrogenic cytokines in irradiated colorectum of two murine strains

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Modulation of fibroblastic cytoskeletal features during wound healing and fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Factors influencing myofibroblast differentiation during wound healing and fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Water transport revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Pathogenesis of fibrosis: type 1 collagen and the skin

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

The skin: its structure and response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Pathophysiology of irradiated skin and breast

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Coactivation of AP-1 activity and TGF-beta1 gene expression in the stress response of normal skin cells to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Expression of transforming growth factor-beta 1 in mouse skin during the acute phase of radiation damage

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor-beta activation in irradiated murine mammary gland

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Early alterations in extracellular matrix and transforming growth factor beta gene expression in mouse lung indicative of late radiation fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Spatial and temporal patterns of expression of epidermal growth factor, transforming growth factor alpha and transforming growth factor beta 1-3 and their receptors in mouse jejunum after radiation treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Ionizing radiation effects on the KG1a primitive hematopoietic cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Chronic cutaneous damage after accidental exposure to ionizing radiation: the Chernobyl experience

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Muscular fibrosis induced after pig skin irradiation with single doses of 192Ir gamma-rays

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Temporal modulation of TGF-beta 1 and beta-actin gene expression in pig skin and muscular fibrosis after ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Abnormal phenotype of cultured fibroblasts in human skin with chronic radiotherapy damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Histopathological and cellular studies of a case of cutaneous radiation syndrome after accidental chronic exposure to a cesium source

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Abnormal proliferation and aging of cultured fibroblasts from pigs with subcutaneous fibrosis induced by gamma irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Long-term expression of transforming growth factor TGF beta 1 in mouse skin after localized beta-irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor beta: a promotor of late connective tissue injury following radiotherapy?

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Plasma transforming growth factor beta1 as a predictor of radiation pneumonitis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes: interrelationship between the alveolar macrophage and the septal fibroblast

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Radiation-induced lung injury in vivo: expression of transforming growth factor-beta precedes fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Immunohistochemical localization of transforming growth factor beta and tumor necrosis factor alpha in the lungs of fibrosis-prone and "non-fibrosing" mice during the latent period and early phase after irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Plasma TGFbeta level in rats after hemithoracic irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Association of transforming growth factor beta (TGF-beta) immunoreactivity with specific histopathologic lesions in subacute and chronic experimental radiation enteropathy.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Changes in transforming growth factor beta1 gene expression and immunoreactivity levels during development of chronic radiation enteropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor-beta 1 expression in irradiated liver

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Radiation-induced changes in transforming growth factor beta and collagen expression in the murine bladder wall and its correlation with bladder function

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor beta (TGF-?) in inflammation: A cause and a cure

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Early and persistent alterations in the expression of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor alpha mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

The Effect of Colchicine on the Accumulation of Hydroxyproline and on Lung Compliance after Irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Effect of interferon gamma on intrahepatic haemodynamics of the cirrhotic rat liver.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Apoptosis and liver fibrosis: antifibrotic strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Interferon gamma in survivors of the Chernobyl power plant accident: new therapeutic option for radiation-induced fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Remission of liver fibrosis by interferon-alpha 2b

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Transforming growth factor-beta in thermally injured patients with hypertrophic scars: effects of interferon alpha-2b.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Regression of hepatic fibrosis in hepatitis C with long-term interferon treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Glucocorticoids and collagen synthesis: comparison of in vivo and cell culture studies

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Amelioration of both early and late radiation-induced damage to pig skin by essential fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD: an experimental study

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Trental (pentoxifylline) relieves pain from postradiation fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Striking regression of subcutaneous fibrosis induced by high doses of gamma rays using a combination of pentoxifylline and alpha-tocopherol: an experimental study

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Effective treatment of the pulmonary fibrosis elicited in mice by bleomycin or silica with anti-CD-11 antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Treatment by human recombinant soluble TNF receptor of pulmonary fibrosis induced by bleomycin or silica in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Preliminary results of a pilot study of pentoxifylline in the treatment of late radiation soft tissue necrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Oxidative damage and fibrogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Control of scarring in adult wounds by neutralising antibody to transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Control of scarring in adult wounds using antisense transforming growth factor-beta 1 oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2800%2900435-1

7 January 2021

10.1016/S0360-3016(00)00435-1

Identifiers

DOI

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30 July 2017

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